Amenorrhea Flashcards
Pregnancy account for how many percentages of amenorrhea
95%
Difference between primary and secondary amenorrhea
Primary, never had menstruation before
Definition of secondary amenorrhea
regular cycle (stopped for at least 3 months), irregular cycles (6 months)
MC of secondary amenorrhea
pregnancy
Definition of ectopic pregnancy
abnormal menses and positive hCG
Labs for hypothalamic-pituitary dysfunction
disruption in GnRH = no FSH and LH
cause of hypothalamic-pituitary amenorrhea
functional (weight loss/malnutrition, excessive exercise), drug-induced, neoplastic (prolactin-secreting pituitary adenoma), psychogenic, head injury, chronic illness, thyroid conditions
Female athlete triad
Low energy availability (with or without disorder eating), menstrual dysfunction (amenorrhea), low bone density
Sheehan syndrome is considered primary or secondary
secondary
postpartum hemorrhage is associated with which disease
sheehan syndrome
prolactin-secreting pituitary is considered primary or secondary?
secondary
5% with hyperprolactinemia and galactorrhea have underlying ________
hypothyroidism
primary ovarian insufficiency
ovarian follicles either exhausted or resistant to stimulation f FSH and LH
Lab results found in primary ovarian insufficiency
high FSH and LH levels
what syndrome is associate with primary ovarian insufficiency
tuner syndrome
what kind of amenorrhea is gonadal dysgenesis
primary
what should you consider in any female with delayed puberty
gonadal dysgenesis
what is the main cause of gonadal dysgenesis
tuner syndrome
what test confirms gonadal dysgenesis
elevated FSH
What kind of amenorrhea is Turner syndrome
MC of primary amenorrhea
What testing can confirm Turner syndrome
karyotyping
treatment for turner syndrome
growth hormone replacement, estrogen and progesterone
what kind of amenorrhea is androgen insensitivity syndrome
primary
complication with androgen insensitivity syndrome
undescended testicles
What is this? primary amenorrhea, absent uterus, normal breast development, scant or absent pubic or axillary hair
androgen insensitivity syndrome
What is MC with primary amenorrhea
alteration of the genital outflow tract
What are the MC anomalies seen in the alteration of the genital outflow tract
imperforate hymen or absent of uterus or vagina
What is asherman syndrome
scarring inside the uterus
vaginal atresia
closed or absent
what is another name for Mullerian agenesis
Mayer Rokitansky-Kuster Hauser syndrome or vaginal agenesis
Clinical presentation of Mullerian agenesis
missing uterus, fallopian tubes and variable malformations of upper vagina
does ovulation occur with Mullerian Agenesis
yes, the ovaries are intact
when to suspect Mullerian Agenesis
primary amenorrhea, absent uterus, normal breast development and normal pubic and axillary hair
What diagnostic test can be ordered for pt with Mullerian agenesis
US to confirm complete or partial absent of cervix, uterus and vagina
Which amenorrhea is asherman syndrome
secondary
What causes Asherman syndrome
injury to pregnant or recently pregnant uterus
what diagnostic test is ordered to confirm Asherman syndrome
hysterosalpingogram
treatment for asherman syndrome
surgery, estrogen therapy, catheter