Alzheimer's disease

Question 1

Most common type of dementia

Answer 1

Alzheimer’s

Question 2

Most common and important degenerative disease of the brain

Answer 2

Alzheimer’s

Question 3

TRUE/FALSE

incidence of AD increases as the age increases?

Answer 3

TRUE

Question 4

Incidence of new cases yearly per 100,000 persons < 60 years old

Answer 4

3/ 100,000: <60 years old

Question 5

Incidence of new cases yearly per 100,000 persons above 60 years old

Answer 5

125/ 100,000: above 60 years old

Question 6

Incidence of new cases yearly per 100,000 persons 60-69 y/o

Answer 6

300/ 100,000: 60-69 y/o

Question 7

Incidence of new cases yearly per 100,000 persons 70-79 y/o

Answer 7

3,200/ 100,000: 70-79 y/o

Question 8

Incidence of new cases yearly per 100,000 persons >80 y/o

Answer 8

10,800/ 10,000: >80 y/o

Question 9

FEMALE/ MALE

Prevalence of AD is 3x more common in _______ because they have more longer life span.

Answer 9

FEMALE

Prevalence of AD is 3x more common in FEMALE because they have more longer life span.

Question 10

Epidemiology risk factors of AD (8)

Answer 10

1. Birth order: oldest child
2. Mother’s age at birth- advanced age
3. Family History of down syndrome
4. Depression
5. Head injury (ex. boxers)
6. Low educational attainment - poor cognitive reserve
7. Vascular risk factors (Diabetes)
8. Familial occurrence (dominant pattern with high degree of penetrance)

Question 11

Onset of Mental changes of AD

Answer 11

always INSIDIOUS onset

Question 12

Major symptoms of AD

Answer 12

Gradual development of forgetfulness

• small day-to-day happenings are not remembered

Question 13

TRUE/ FALSE

Remote memory is preserved and recent one’s is lost

Answer 13

TRUE

Question 14

This law explains why remote memories are preserved and recent memories are lost

Answer 14

Ribot Law of Memory