Altered mood Flashcards

1
Q

What is the male:female ratio of people affected by depression?

A

M:F 1:2

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2
Q

How long does someone need to have been experiencing symtpoms to be diagnosed with depression?

A

2 weeks

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3
Q

What are the three core symtpoms of depression?

A
  1. Low mood
  2. Anhedonia
  3. Anergia
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4
Q

What is anhedonia?

A

Inability to feel pleasure from normally pleasurable activities

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5
Q

What is anergia?

A

Abnormal lack of energy

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6
Q

Other than the three core symptoms, what are the other symptoms of depression?

A

Loss of confidence/self esteem

Self-reproach/excessive guilt

Recurrent thoughts death, suicide, suicidal behaviour

Reduced concentration

Change in psychomotor activity

Sleep disturbance

Change in appetite

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7
Q

What are the symptoms of the somatic syndrome of depression, and how many are needed for diagnosis of somatic syndrome?

A

Marked loss of interest or pleasure in activities that are normally pleasurable

Lack of emotional reactions to events or activities that normally produce an emotional response

Waking in the morning 2 hours or more before the usual time

Depression worse in the morning (diurnal variation)

Objective evidence of marked psychomotor retardation or agitation (remarked on or reported by other people)

Marked loss of appetite

Weight loss (5 % or more of body weight in the past month)

Marked loss of libido

Need 4 or more for diagnosis

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8
Q

How might someone with depressions’ speech be affected?

A

Reduced rate

Lowered in pitch

Reduced in volume

Reduced intonation (monotonous)

Increased speech latency

Limited content

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9
Q

How might someone with depressions’ thinking be affected?

A

Slow thought, poverty of thought

Negative cognitive distortions

Obsessions, ruminations

Thoughts of death, excessive guilt

Delusions –usually mood congruent: guilt, nihilism, hypochondriasis

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10
Q

How would someone with depressions’ perception be noted on mental state examination?

A

Hallucinations in any modality - usually mood-congruent

Auditory most common- second person and derogatory

Illusions

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11
Q

How might someone with depressions’ cognition be affected?

A

Subjectively- slow thinking, poor memory

Objectively- deficits in working memory, planning and attention

“Pseudodementia”

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12
Q

What is mixed anxiety and depression?

A

Symptoms of anxiety and depression not significant enough to justify individual diagnosis

Most common diagnosis

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13
Q

What is dysthymia?

A

Persistent mild depression: tired and depressed for months at a time but usually able to cope with the demands of life

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14
Q

What are the features of mania?

A

Elevated mood

Increased energy

Overactivity

Pressure of speech

Decreased need for sleep

Disinhibition

Distractability

Inflated self esteem

Grandiose ideas

Taking risks

Overspending

Perceptual disturbance

Irritability/suspicion

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15
Q

What is hypomania?

A

A mild form of mania, marked by elevation and hyperactivity

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16
Q

What is the definiton of bipolar affective disorder?

A

A mental condition marked by alternating periods of elation and depression

Two or more episodes mania +/- depression

17
Q

What are some of the non-psychotic symptoms associated with mania?

A

Overactive

Unable to sleep

Excessive shopping

High ego

Talking lots

18
Q

What are some of the psychotic symptoms associated with mania?

A

Mood congruent delusions- often grandiose, religious, suspicious

Mood congruent hallucinations

Flight of ideas, incomprehensible speech

Severe sustained physical activity

Aggressive behaviour

Self neglect, dehydration

19
Q

What is the mean age of onset of bipolar affective disorder?

A

21

20
Q

What is the median length of untreated episodes of bipolar affective disorder?

A

3 months

21
Q

What is the risk of suicide with bipolar disorder?

A

12-15% lifetime risk

22
Q

What is schizoaffective disorder?

A

Some symptoms of schizophrenia and affective (mood) disorder but insufficient to justify either diagnosis alone

23
Q

What is cyclothymia?

A

Persistant instability of mood: numerous periods of mild depression and mild elation

24
Q

What have twin studies shown the heritability of bipolar disorder to be?

A

80%

25
Q

Which abnormality of the hypothalamic-pituitary-adrenal (HPA) axis is associated with depression?

A

Major depression is associated with adrenal enlargement, increased secretion of cortisol and adrenocorticotrophic hormone, and cortisol non-suppression following dexamethasone administration

26
Q

Which neurotransmitter is most likely to be low in depression?

A

5-hydroxytryptamine or seratonin