Altered Cellular and Tissue Biology Flashcards

1
Q

most important thing about the Plasma Membrane

A

semi permeable

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2
Q

primary intracellular ion

A

potassium K

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3
Q

primary extracellular ion

A

sodium Na

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4
Q

Aerobic metabolism

A

.

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5
Q

Cell membrane semi permeability

A

.

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6
Q

Response to injury/foreign body

invasion

A

.

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7
Q

Metabolism is normally

A

aerobic

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8
Q

Metabolism is normally aerobic (with ___

as byproduct exhaled by the ___)

A

CO 2, lungs

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9
Q

metabolism becomes anaerobic when

A

When oxygen is not available in amounts

adequate for metabolic needs, metabolism

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10
Q

during anaerobic metabolism byproducts are

A

lactic and pyruvic acids

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11
Q

Acid production changes pH in the blood

triggering

A

the sympathetic nervous system

and “fight or flight” symptoms

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12
Q

Semi permeable cell membrane generally allows passage in and out of cell of

A

H 2 O & dissolved substances (solutes, such as electrolytes)

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13
Q

Semi permeable cell membrane does not normally permit passage of

A

large molecules (plasma proteins, RBCs, etc.)

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14
Q

Semi permeable cell membrane: what is the big thing that disease changes

A

what is able to flow through the membrane

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15
Q

Cell membrane: Semi permeable movement of water and solutes (electrolytes) is by means of

A

active or passive transport

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16
Q

With injury , cell membrane becomes permeable to larger substances such as ____, resulting in the inflammatory response & edema

A

WBCs and albumin

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17
Q

With injury , cell membrane becomes permeable to larger substances such as WBCs and albumin, resulting in

A

the inflammatory response & edema

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18
Q

Cellular Communication: Direct linkup

A

.

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19
Q

Cellular Communication: Gap junctions (contact signaling)

A

.

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20
Q

Cellular Communication: Chemical signaling: Hormonal: examples

A

TSH, EPO

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21
Q

Cellular Communication: Chemical signaling: Neurohormonal: examples

A

Angiotension II

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22
Q

Cellular Communication: Chemical signaling: Paracrine

A

local chemical mediators that act only on nearby cells

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23
Q

Cellular Communication: Chemical signaling: Autocrine

A

self stimulation by cells

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24
Q

Cellular Communication: Neurotransmitters: 4 examples

A

acetylcholine, serotonin, histamine, norepinephrine, etc.

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25
Active or Passive? Diffusion
Passive
26
Active or Passive? Filtration
Passive
27
Active or Passive? Osmosis
Passive
28
Active or Passive? Tonicity (solutes/solvent)
Passive
29
Active or Passive? Passive mediated transport (facilitated transport)
Passive
30
Diffusion
.
31
Filtration
.
32
Osmosis
.
33
Tonicity
.
34
Passive mediated transport
.
35
Osmolarity
measures serum concentration (how much stuff is in the solvent)
36
The movement of solutes (O 2 , CO 2 , urea, electrolytes, etc.) is relative to ___ on the other side of the membrane
size, solubility, electrical properties and concentration
37
Active transport pumps: Examples are sodium pump and
Insulin to transport glucose into cells
38
2 kinds of Hypoxic injury
Ischemia | Anoxia
39
Reperfusion injury
.
40
Cellular responses to hypoxic injury
1. Decrease in ATP, causing failure of sodium potassium pump and sodium calcium exchange 2. Cellular swelling
41
Cell response to injury: Injury or foreign invasion triggers | _____response
inflammatory
42
Cell response to injury: Injury or foreign invasion triggers inflammatory response. Then you have
altered cell membrane
43
Cell response to injury: Injury or foreign invasion triggers inflammatory response. Then you have altered cell membrane. That causes
edema
44
Do i need to know slide 16?
.
45
where cell repair takes place
nucleus
46
2 important Cellular functions: m___ and c____
Movement | Conductivity
47
Aerobic metabolism: Cell needs oxygen to metabolize. The normal byproduct is
CO2
48
Aerobic metabolism: Cell needs oxygen to metabolize. The normal byproduct is CO2. If the cells do not have O2 they go into a____
anaerobic
49
Aerobic metabolism: Cell needs oxygen to metabolize. The normal byproduct is CO2. If the cells do not have O2 they go into anaerobic. They produce ___ and ___
lactic acid and pyruvic acid
50
Star the cellular metabolism slide
.
51
Acidosis triggers receptors in the ___ and ___ to stimulate the brain to release catecholamines (epi and norepinephrine) to start the flight or fight response
aorta and carotid
52
Acidosis triggers receptors in the aorta and carotid to stimulate the brain to release ____ to start the flight or fight response
catecholamines (epi and norepinephrine)
53
_____ is the building material of cell membrane and myelin sheaths
Cholesterol
54
____ is the most important plasma protein
Albumin
55
Albumin is the most important plasma protein. Fibrinogen and globulin are the other two plasma proteins. They’re made in the ___
liver
56
Edema is when fluid goes to ____ ___
interstitial spaces
57
edema causes BP to
drop (because the fluids not in the vascular anymore)
58
O2 is carried around the body in h____
hemoglobin
59
Exercise promotes the movement of glucose into the cells, so you need less ____
insulin
60
Ischemia vs anoxia
Ischemia- decreased oxygen to the tissues | Anoxia is NO oxygen to the tissues
61
Hypoxemia vs hypoxia
Hypoxemia is low O2 in the blood | Hypoxia is low O2 in the tissue
62
What is thrombosis vs embolism
embolism is when its moving