Alpha1-blockers

Question 1

Alpha1-blockers Drug Names

Answer 1

Doxazosin
Prazosin
Terazosin

“-azosin”

Question 2

Alpha1-blockers Therapeutic Actions

Answer 2

• Blocks Alpha1 receptors sites
• Decrease vascular tone resulting in vasodilation
• Decrease BP

Question 3

Alpha1-blockers Indications

Answer 3

• HTN

Question 4

Alpha1-blockers Contraindications and Cautions

Answer 4

Contraindication:
• Allergy
• Heart Failure
• Renal failure or hepatic impairment

Question 5

Alpha1-blockers DDI

Answer 5

• Vasodilators /antihypertensives

Question 6

Alpha1-blockers Adverse Effects

Answer 6

• CNS
• CV
• GI/GU

Question 7

Alpha1-blockers:

Assessment

Answer 7

Hx: allergy, contraindications/cautions
Physical: vital signs, weight, BP, RR, abdominal, urinary, perfusion, ECG (baseline)
Labs: electrolyte levels, renal and hepatic function, glucose

Question 8

Alpha1-blockers:

Diagnosis

Answer 8

• Acute pain
• Ineffective tissue perfusion
• Decreased cardiac output
• Risk for injury
• Risk for activity intolerance
• Non-compliance
• Disturbed sensory perception
• Deficient knowledge

Question 9

Alpha1-blockers:

Implementation

Answer 9

• Take apical pulse before: hold if <60bpm
• Do not abruptly stop medication (rebound hypertension)
• Encourage lifestyle changes
• Change positions slowly
• Do not crush ER formulations
• Monitor vitals
• Provide patient teaching

Question 10

Alpha1-blockers:

Evaluation

Answer 10

Response to the drug
Adverse effects
Effectiveness of comfort measures Compliance with the regimen
Effectiveness of the teaching plan