Allergy Flashcards
Type 1 Allergy is an immediate reaction and occurs within minutes to 2 hours after exposure. True or false?
True
What are 4 routes of exposure in type 1 allergy?
- skin contact
- ingestion
- injection
- inhalation
pathophysiology of allergic reaction type I
blah blah blah
clinical presentation of type 1 hypersensitivity reaction
- angioedema
- urticaria
- wheezing/asthma
- anaphylazis
Investigations?
- history
- specific IgE RAST
- skin prick or prick-prick testing
- challenge test
- serum mast cell tryptase level during anaphylaxis
What is RAST?
radioallergosorbent test is a blood test to detect specific IgE antibodies
skin prick/prick-prick testing what is it and what is pros?
- drop of liquid on arm that contains the substance you think youre allergic to
- cheap and quick
- specificity + sensitivity v high
- relatively low anaphylaxis risk
challenge test
make them eat allergen/ ingest/ skin contact
adrenaline autoinjector
for anaphylaxis
300ug adults
150ug children
should always get 2
Coeliac’s and eosinophilic gastroenteritis are mediated by IgE and are are Type I hypersensitivity reactions. True or false?
False
Type IV allergy
- delayed hypersensitivity
- antigen specific
- T cell mediated
- allergic contact dermatitis
How long after exposure do type IV allergies show up?
24-48hrs
