All Paramedic drugs Flashcards
classification for amiodarone
class III antidysrhythmic potassium channel blocker
trade name for Amiodarone
Cordarone
mechanism of action of amiodarone
antidysrhythmic that directly acts on cardiac tissues. it prolongs the duration of the acton potential and refractoy period by blocking potassium channels without affecting the resting membrane potential. it blocks sodium channels. it relaxes vascular smooth muscles decreasing vascular resistance and increasing coronary blood flow and blocks the effects of sympathetic stimulation
indications for Amiodarone
life threatening ventricular and supraventricular dysrhythmias
VF, VT, A-Fib, A-Flutter, SVT, WPW
Contraindications for amiodarone
hypersensitivity
cardiogenic shock
severe sinus bradycardia
AV Block
Precautions for Amiodarone
use with caution in
severe liver disease
pregnancy
nursing mothers
side effects for Amiodarone
Prolonged QT interval permanent blindness fatigue bradycardia angioedema
dosage and route of Amiodarone
Adult with pulse: 150 mg (in 50 - 100ml NS) IV infusion over 10 min
may repeat dose after 10 min
Pulseless: 300 mg IVP repeat in 3-5 min at 150mg IVP
Pedi: 5mg/kgIV/IO
trade name for Lorazepam
Ativan
classification of Lorazepam
Benzodiazepine
Mechanism of Action of Lorazepam
Lorazepam is the most potent of benzodiazepines
it acts as an anxiolytic, sedative, hypnotic and skeletal muscle relaxant
it intensifies the effects of GABA
because of its short half life it is the preferred benzodiazepine for the treatment of pediatric seizures
indications for Lorazepam
seizures (status epilepticcus)
to induce sedation prior to painful procedures
acute anxiety
contraindications for lorazepam
hypersensitivity to benzodiazepines acute narrow angled glaucoma coma shock acute alcohol intoxication
precautions for Lorazepam
Renal or hepatic impairment
Myasthenia gravis
COPD
side effects for Lorazepam
amnesia sedation hypertension hypotension blurred vision confusion
