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1
Q

NS and endocrine

A
  1. CNS: Brain for higher functions, Spinal chord for reflex arcs
  2. ## PNS: Autonomic and Somatic
  3. Endocrine: Glands release hormones into blood
  4. Endocrine and ANS working together in flight or fight
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2
Q

Neurones and transmission

A
  1. Types and structure of neurones and AP
    - synapses
  2. Neurotransmitters
  3. Excitation and inhibition
  4. Summation
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3
Q

Localisation A01

A
  1. Localisation v Hollsitic
  2. Hemispheres: left controls right. Also Cerebral cortex is highly developed
  3. Lobes and associated areas
  4. Language areas in left: Broca’s and Wernickes: aphasia
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4
Q

Localisation A03

A
  1. Brain scan: Wernickes for listening. Separate LTM stores
  2. Phieas gage: frontal lobe, went all moody
  3. Rats showed higher function such as learning not localised
  4. Plasticity
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5
Q

Plasticity A01

A
  1. Ability to rewire through synaptic pruning
  2. Research into: Maguires Taxis, Med students, mono lingual
  3. Functional recovery: spontaneous recovery but then need therapy
  4. Process of functional recovery
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6
Q

Plasticity A03

A
  1. Practical application in neurorehabilation
  2. Negative plasticity: Drugs: > cog function and + risk of dementia. 70% amputees have PL syndrome. Due to reorganisation of somatosensory cortex
  3. Age: 40 hours, 40-60 yrs old, fMRI: reduced activity in motor cortex
  4. Hubble and Wiesel
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7
Q

Split brain A01

A
  1. Allowed study of hemispheric lateralisation through split brain research
  2. Procedure: left right VF
  3. Findings: recognition by touch and Describe what you see
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8
Q

Split brain A03

A
  1. Showed lateralised function: left analyistic and verbal, right spatial and music
  2. Good Methodology
  3. Cannot generalise due to poor control (11 patients, control had no epilepsy)
  4. Plasticity
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9
Q

A01 circadian rhythms

A
  1. Governd by: endo pacemakers and exo zeitgabers (entrain)
  2. Research into free-running sleep wake: siffre: 25 hour
  3. Similar study in bunker: 25 hour
  4. Altered clock to 22 hour: only 1 adjusted so shows free-running circadian rhythm is powerful
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10
Q

A03 circadian rhythms

A
  1. Shift work: disruption to sleep/wake makes 3x more likely CVD (not casual)
  2. Body processes such as hormones effect uptake of drugs
  3. Hard to generalise due to small samples and lack of control
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11
Q

A01 infradian and ultradian rhythms

A
  1. Mensural cycle governed by monthly hormone changes
  2. Research into exogenous factors: pheromones: 9 women, 68% experienced change
  3. SAD: depression in winter months due to melatonin which disrupts serotonin
  4. EEG: 90 mins, 5 stages
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12
Q

A03 infadian and ultraidian

A
  1. Evolutionary basis of menstrual: collective care v competition
  2. Methodological issues with pheromone study: too many confounding variables that effect period: also self-report and small sample
  3. EEG evidence highly controlled, replicated made up for initial small sample
  4. Light box’s for SAD: 60% improved, 30% placebo
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13
Q

Endogenous pacemakers on sleep/wake A01

A
  1. SCN: primary EP, lies above optic chiasm: even while eyes closed- relays to pineal gland
  2. ## Animal studues: SCN In 30 chipmunks, most dead in habitat after 80 days: awake at wrong timeMutant hamsters with 20-hour sleep/wake.
    Both show importance of SCN on sleep/wake
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14
Q

Exogenous zeitgabers on sleep/wake

A
  1. ## External factors that entrain circadian rhythmLight: effects SCN, also people woken up by photoreceptors on knees

Social cues: babies: mealtimes and and bedtimes

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15
Q

A03 of endogenous pacemakers and exogenous zietgabers on sleep wake

A
  1. Peripheral oscillators influenced by SCN but also act independently: mice feeding times could alter CirRhy in liver by 12hrs. Suggest not just SCN
  2. Ethical implications of animal studies as well as generalisability
  3. Influence of EZ overstated: blind man and 22 hour clock
  4. Invalid to separate them: interactinalsit system as we are never fully in the dark for long
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