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CLASP Alcohol > Alcohol Formative 2 > Flashcards

Alcohol Formative 2 Flashcards

1
Q

Which nutritional deficiency, often found following chronic alcohol abuse, is associated with Wernicke-Korsakoff syndrome?

A

Thiamine Deficiency

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2
Q 
Which of these medications is used for Medically Assisted Withdrawal?
1 - Disulfiram
2 - CHlorodiazepoxide
3 - Haloperidol
4 - Lorazepam
A

Chlorodiazepoxide

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3
Q

Which clotting factor is NOT made in the liver?

A

VIII

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4
Q

What is the definition of binge drinking for a woman/man?

A

greater than 8 units in one day

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5
Q

What is the name for the abnormal gait seen in Wernicke’s syndrome?

A

Ataxic gait

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6
Q

Fibrosis cirrhosis of the liver is mediated by which type of cell?

A

Interstitial cells of Ito

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7
Q

The drug Antabuse, used to treat alcoholism, works by inhibiting which enzyme?

A

Aldehyde dehydrogenase

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8
Q

What can be used to treat patients with a raised osmolal gap due to toxic alcohol ingestion?

A

Ethanol can be used if the toxic alcohol ingested is methanol (e.g. in anti-freeze)

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9
Q

Are there any substances which can speed up elimination of alcohol from the body?

A

Food is the only substance

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10
Q

Which biochemical finding, commonly seen in patients with established alcoholic liver disease, causes clinical jaundice?

A

Hyperbilirubinaemia

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11
Q

In a patient with alcoholic liver disease presenting with an upper GI bleed, which test proves the most useful information about liver synthetic function?
1 - prothrombin time
2 - triglycerides
3 - serum urea

A

prothrombin time

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12
Q

Facal flushing and the general feeling of being unwell when drinking is caused by which substance?

A

Aldehyde

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13
Q

What is the safe limit of alcohol intake recommended by the UK Chief Medical Officer during pregnancy?

A

0 units

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14
Q

In the process of death certification, which conditions are listed under part 2?

A

Conditions contributing to, but not directly responsible for death

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15
Q

How many units are in a 70cl bottle of 40% vodka?

A

28 - units = (% x volume) divided by 1000

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16
Q 
Which of the following is a useful screening tool for Alcohol Dependence Disorder?
1 - PHQ-9
2 - DAST
4 - AUDIT
4 - COWS
A

AUDIT

17
Q

What is the usual time-scale for the development of Delirium Tremens?

A

3-10 days

18
Q

Why does alcohol cause diuresis?

A

Due to decreased ADH levels

19
Q

Which of the following drugs leads to faster rate of alcohol absorption?
1 - Omeprazole
2 - Penicillin
3 - Domperidone

A

Domperidone - used to treat gastroparesis, nausea and vomiting by increasing peristalsis

CLASP Alcohol (2 decks)

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