alcohol and the brain Flashcards

1
Q

wernicke’s encephalopathy caused by

A

acute thiamine deficiency

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2
Q

pathological findings in the brain in wernicke’s

A

MICROvascular lesions in the 3rd and 4th ventricles, periaqueductal grey amtter, brainstem, cerebellum

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3
Q

features of wernicke’s encephalopathy

A
Ataxia
nystagmus
ophthalmoplefia
global confusional state
neuripathy
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4
Q

causes of wernicke’s encephatlopathy

A

chronic etOH abuse
hyperemesis gravidarum
dialysis
gastric cancer

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5
Q

treatment of wernickes

A

IV thiamine

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6
Q

how many with wernickes develop Korsakoff’s

A

80%

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7
Q

features of korsakoff’s?

A
markedly impaired short-term recall
anterograde amnesia
variable retrograde amnesia
registration normal
lack of insight
cinfabulation common
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8
Q

other causes of korsakoff’s

A

CO poisoning

HSV encephalitis

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