Alcohol and the brain Flashcards
How does alcohol effect brain chemistry?
By altering the levels of neurotransmitters
What are neurotransmitters?
chemical messengers that transmit the signals throughout the body that control thought processes, behaviour and emotion (in case you had forgotten)
What do excitatory neurotransmitters do?
they stimulate brain electrical activity
What do inhibitory neurotransmitters do?
they decrease brain electrical activit
Alcohol increases the effects of which kind of neurotransmitter?
Inhibatory, GABA
Remember it is a depressant hypnotic
Remember it is a depressant hypnotic
What does GABA cause?
causes the sluggish movements and slurred speech we associate with alcohol
What does alcohol inhibit?
the excitatory neurotransmitter glutamate
Alcohol increases the amount of the chemical WHAT in the brain’s reward centre?
Dopamine, which creates the feeling of pleasure that occurs when someone takes a drink.
What is the VTA?
ventral tegmental area
What is a DA neuron?
Dopaminergic neuron
What is the NP?
Nigrostriatal pathway
Acute ethanol intake can increase DA neuron discharge in the NP and VTA; this discharge is reduced during alcohol withdrawal and restored after restarting ethanol intake (Ma & Zhu, 2014).
Acute ethanol intake can increase DA neuron discharge in the NP and VTA; this discharge is reduced during alcohol withdrawal and restored after restarting ethanol intake (Ma & Zhu, 2014).
Short-term alcohol exposure tilts the balance toward inhibition by both enhancing the function of inhibitory neurotransmitters and neuromodulators (i.e., GABA, glycine, and adenosine)
It additionally decreases the function of excitatory neurotransmitters (i.e., glutamate and aspartate).
Short-term alcohol exposure tilts the balance toward inhibition by both enhancing the function of inhibitory neurotransmitters and neuromodulators (i.e., GABA, glycine, and adenosine)
It additionally decreases the function of excitatory neurotransmitters (i.e., glutamate and aspartate).
Alcohol stimulates the activity of endogenous opioid peptides, leading indirectly to the activation of dopaminergic neurons
Alcohol stimulates the activity of endogenous opioid peptides, leading indirectly to the activation of dopaminergic neurons