Alcohol Flashcards
1
Q
Primary pathway for ethanol oxidation to acetaldehyde; rate limiting; Primarily in the liver
A
Alcohol Dehydrogenase Pathway
2
Q
What order are the kinetics of ethanol elimination?
A
Zero order
3
Q
Which enzyme metabolized Acetaldehyde?
A
Aldehyde Dehydrogenase (ALDH)
4
Q
Inhibits aldehyde dehydrogenase; aversion therapy for alcoholism
A
Disulfiram
5
Q
Which class of drugs is used for withdrawal symptoms of alcohol to prevent seizures, delirium and arrhythmias?
A
Benzodiazepines: diazepam, chlordiazepoxide
6
Q
Used to reduce the urge to drink; opioid receptor antagonist; works best with psychosocial therapy
A
Naltrexone
7
Q
Decreases drinking frequency and reduces relapse; GABA mimetic; well tolerated; SE– Diarrhea
A
Acamprosate
