albuterol sulfate - proventil HFA, proair HFA

Question 1

drug classification

Answer 1

sympathomimetic, symphathetic agonst (beta 2 selective)

Question 2

mechanism of action

Answer 2

beta 2 agonist- promotes sympathetic stimulation of bronchial smooth muscle cells, reducing interaction between actin and myosin causing smooth muscle relaxation- bronchodialation

Question 3

onset

Answer 3

5-15min

Question 4

peak

Answer 4

1.0-1.5 h

Question 5

duration

Answer 5

3-6 h

Question 6

half life

Answer 6

less than 3h

Question 7

indications , field use

Answer 7

reversible bronchospasm associatied with COPD and asthma

wheezing associated with allergic reaction/anaphylaxis

Question 8

contraindications

Answer 8

symptomatic tachycardia

hypersensitivity

Question 9

side effects, adverse reactions

Answer 9

anxiety, headache, palpitations, sweating, dizziness, nervousness, tremor, HTN, dysrhythmias, chest pain, n+v

Question 10

adult and pedi dose

Answer 10

2.5 mg in 2.5 ml NS nebulized with oxygen 8 LPM

Question 11

precautions

Answer 11

may worsen cardiac asthma and precipitate dysryhtmias,

consider 12 lead with chest pain

Question 12

drug on drug interactions

Answer 12

side effects may increase with other sympathetic agonists,
beta blockers may blunt effects of this drug
MAOI and TCA may potentiate cardiovascular effects