Albuterol (Proventil, Ventolin)

Question 1

Class

Answer 1

Sympathomimetic, bronchodilator

Question 2

Mechanism of Action

Answer 2

Selective beta 2 agonist of adrenergic receptors, bronchiole and peripheral vasculature smooth muscle relaxant

Question 3

Indications

Answer 3

Bronchospasm in COPD pts, prevention of exercised induced asthma

Question 4

Contraindications

Answer 4

Hypersensitivity, tachycardia, dysrhythmias especially due to digitalis, Synergistic with other sympathomimetics

Question 5

Adverse Reactions

Answer 5

Dose related HA, fatigue, lightheadedness, irritability, restlessness, aggressive behavior, pulmonary edema, hoarseness, nasal congestion, increased sputum, HTN, tachycardia, dysrhythmias, cox, palpitations, nausea/vomiting, dry mouth epigastric px, tremors

Question 6

Drug interactions

Answer 6

Tricyclic antidepressants potentiate vascular effects, Beta-blockers are antagonist and may block pulmonary effect. May potentiate hypokalemia

Question 7

How supplied

Answer 7

MDI 90mcg/spray, Nebulized .5% (5mg/ml) or (.083%) 2.5mg in 3ml neb.

Question 8

Dosage and Administration

Answer 8

Adult: 2.5mg neb over 10-15 min. MDI 1-2 inhalations (90-180 mcg)
Ped: <20kg - 1.25mg neb over 20 min, repeat once in 20 min.

Question 9

Duration of Action

Answer 9

Onset:15 min
Peak: 30 min - 2 hr
Duration: 3-4 hrs

Question 10

Special Considerations

Answer 10

Pregnancy Cat C

May precipitate angina and dysrhythmias, administer only via inhalation