AKI Flashcards

1
Q

What are the groups of causes of AKI?

A

Pre-renal - blood flow to kidneys

Renal - Damage to kidney parenchyma

Post-renal - Problems with urine outlfow

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2
Q

What are the pre-renal causes of AKI?

A

1) Reduced circulating volume (hypotension, dehydration, congestive heart failure)
2) Arterial occlusion
3) Vasomotor (NSAIDS/ACE i’s)

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3
Q

What are the renal causes of AKI?

A
  • Acute Tubular Necrosis
  • Toxin-related
  • Acute interstitial nephritis
  • Acute glomerulonephritis
  • Myeloma
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4
Q

What are the post-renal causes of AKI?

A

Obstruction:

  • Intraluminal (calculi)
  • Intramural (malignancy, ureteric stricture)
  • Extramural
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5
Q

What are the signs and symptoms of AKI?

A
  • Oliguria or anuria
  • Nausea and vomitting
  • Confusion
  • Hypertension
  • Abdominal/flank pain
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6
Q

What are the investigations and assessment of AKI?

A
  • GFR
  • U&E’s
  • FBC
  • Blood gas
  • Urinalysis (Bence Jones Protein, blood, protein)
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7
Q

What is the treatment for AKI?

A
  • Maintain fluids & renal blood flow
  • Monitor electrolytes
  • Treat underlying cause
  • Stop nephrotoxic drugs
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