Aki

Question 1

Stage 1 AKI UO: <____ ml/kg per h for ___h

Answer 1

<0.5 ; 6-12

Question 2

Stage 2 AKI UO
<____mL/kg per h for ____h

Answer 2

0.5 , 12

Question 3

Pre renal AKI. 2 Reasons why BUN and SCr increases

Answer 3

Inadequate:
renal BF
Intraglomerular hydrostatic pressure

Question 4

Prolonged Prerenal azotemia leads to

Answer 4

Acute tubular necrosis

Question 5

A Decrease in CO leads to renal vasodilation/vasoconstriction? And salt and water reabsorption/excretion?

Answer 5

Constriction, reabsorption

Question 6

Glomerular filtration is maintained despite reduced RBF by Ang2 mediated renal afferent/efferent vasodilation/vasoconstriction?

(Ipair mo sino mag dilate, constrict)

Answer 6

Efferent, constriction
Afferent, dilation

Question 7

Renal autoregulation fails once SNP is below ____mmHg

Answer 7

80

Question 8

NSAIDs inhibit the production of ____, limiting renal ______ vaso____

Answer 8

Prostaglandin
Afferent, vdilation
Therefore mag constrict sya

Question 9

ARBS limit ____ vaso____

Answer 9

Efferent vasoconstriction therefore mag dilate sya

Question 10

Most common causes of intrinsic AKI
1
2
3

Answer 10

Sepsis
Ischemia
Nephrotoxins

Question 11

Kidneys receive __% CO and account for __% resting 02 consumption

Answer 11

20, 10

Question 12

What segment of the proximal tubule is considered to be very metabolically active? S1, S2, S3?

Answer 12

S3

Question 13

Mechanism of cardiopulmonary bypass in AKI. Give 1

Answer 13

Answers:
Hemolysis causing pigment nephropathy
Activation of leukocytes and inflammation
Aortic injury causing atheroemboli

Question 14

Individuals undergoing massive fluid resuscitation for trauma, burns, and acute pancreatitis can also develop abdominal compartment syndrome, where markedly elevated intraabdominal pressures, usually >____mmHg, lead to renal vein compression and reduced GFR.

Answer 14

20

Question 15

Contrast nephropathy
Rise in SCr beginning ___
Peaks in ___
Resolves within ____

Answer 15

Begins at 24-48 hrs
Peaks in 3-5 days
Resolves within 1 week

Question 16

Electrolyte imbalance in AKI associated with antibiotic use

Answer 16

Hypomagnesemia

Question 17

Most common protein in urine

Answer 17

Tamm-Horsfall or uromodulin from the TaL

Question 18

Massive uric acid level. Give number

Answer 18

15 mg/dl

Question 19

Electrolyte imbalance in multiple myeloma

Answer 19

Hypercalcemia

Question 20

With many of the epithelial cell toxins such as aminoglycoside antibiotics and cisplatin, the rise in SCr is characteristically delayed for ____ to ___ after initial exposure.

Answer 20

3-5 days to 2 weeks

Question 21

Hallmark of AKI

Answer 21

Increase BUN

Question 22

Recovery from AKI is often heralded as

Answer 22

Increase in UO

Question 23

Complication of AKI. Hyponat or hypernat

Answer 23

Hypo ofc

Question 24

Complication of AKI. Hypo/hyper phosphatemia and hypo/hyper calcemia

Answer 24

Hyperphosphatemia
Hypocalcemia