Airway Obstruction + Ventilation Flashcards
Medullary center
Dorsal respiratory Group DRG
Controls inspiratory movements + timing
Medullary Center
Ventral respiratory group VRG
Controls voluntary forced exhalation + up inspiration. Inactive in quiet breathing
Pontine Centers
Pneumotaxic center
- Coordinates speed of inhalation/ exhalation. *Sends inhibitory impulses to DRG.
- Fine tuning of RR
Apneustic Center
- Inspiration
- depth of breathing
- signals to DRG in medulla
- stimulatory impulses to inspiratory area
- inhibited by stretch receptors
- cyclic, gradual increase then decrease
* HF, Stroke, Kidney failure, opiate, high altitude
Cheyne-Stokes Breathing
HYPERCAPNEA
CNS sleep apnea
2ndary
Central sleep apnea
Tx
CPAP
Obesity Hypoventilation
Gradual high PCO2, makes you sleepy
- BMI = >35-40
- daytime hypoventilation (UP CO2, Low O2)
- Sleep-disordered breathing
- hypercapnia = 20% dead in 18 months if untreated
Obesity Hypoventilation Syndrome (OHS)
Path
- leptin deficiency/resistance (hunger UP)
- more work load
- upper airway obstruction
=
Poor ventilatory response
HYPERCAPNEA + HYPOXEMIA
Obesity-Hypoventilation Syndrome
Tx
- weight loss
- CPAP (exhalation)
- BIPAP (inhalation + exhalation)
- tracheostomy w/ nighttime positive pressure ventilation
Hyperpnia
- NOT hyperventilation syndrome
* UP depth+rate of breathing = sepsis, fever, hypoxemia
Central Sleep Apnea
- brain stop sending signals to the muscles of respiration
- Lack of abnormal + thoracic movement
- primary : Ondine’s Curse to Palemon
Apnea =
Cessation of breathing >10 seconds
*hypopnea = DOWN airflow w/ DOWN O2 Sat >4%
Apnea-hypopnea index (AHI)
- severity of sleep apnea
- 0-4 = Normal
- 5-14 = Mild
- 15-29 = Moderate (CPAP)
- 30+ = Severe (CPAP)
*Obesity
*Loud / frequent snoring
(Only if crescendo)
*Silent Pauses in breathing
*Choking/gasping
*Daytime sleepiness/fatigue
*Unrefreshing sleep
*insomnia
*Morning headaches
(Back of head = HTN)
*nocturia (waking to urinate)
Sleep Disorder Breathing
Signs + Symptoms
Acute respiratory failure
- pneumonia
- ARDS
- Status asthmaticus
- Acute COPD exacerbation
VENTILATE
Acute on Chronic repsiratory failure
Hypercarbia = OHS
VENTILATE