AIHA Flashcards

1
Q

Warm vs Cold

A

Cold: IgM, PBS shows RBC aggregates
Warm: IgG

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2
Q

Evans syndrome

A

ITP + AIHA

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3
Q

ITP treatments

A

First line: prednisone, taper over 4 weeks, or dexamethasone 40mg pro x 4 days, anti-Rh(D) Ig IV, IVIG x 2-3 days
Second line: splenectomy if ITP >6 mo, rituxamab, Romiplostim, or eltrombopag, AZA, cyclophosphamide,
Bleeding: aminocaproic acid, methylprednisolone x 3days, IVIg, platelet transfusion,
Refractory: romiplostim, or eltrombopag, autologous HSCT

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