Ags & Abs Flashcards
1
Q
Haptens
A
small molecules that cannot induce an immune response alone (bind to MHC but can’t activate T cells)
2
Q
Superantigens
A
bind to class II MHC, lead to hyper-activation of immune system, so many cytokines from T cells
3
Q
Allelic differences
A
affect H chains of Abs, all have IgG but some subtle differences between people
4
Q
What Ab is first produced in primary response?
A
IgM (5-10% of serum Abs)
5
Q
What Ab is predominant in secondary response?
A
IgG (80% of serum Abs)
6
Q
What other Abs involved in secondary response?
A
IgA (mucosal) & IgE (allergies) & IgD (membrane bound always on B cells)
7
Q
How do Ags & Abs bind?
A
H bonds
electrostatic bonds
Van der Waals
Hydrophobic Forces
