Ageing and the body Flashcards

1
Q

How does ageing affect health care?

A
  • Natural process - happens to everyone
  • Body systems change
  • Impacts on how well body copes with new and ongoing insults
  • Impacts on how we treat and manage patients
  • Implications for ongoing care - increasingly challenging
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2
Q

How does ageing affect the skin?

A
  • Elastic tissue becomes less effective as we age
  • Skin becomes less tight and thinner
  • More susceptible to damage and therefore more fragile
  • Causes skin to tear and bruise easily
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3
Q

How does ageing affect the respiratory system?

A
  • Elasticity in lungs is important for normal function
  • Lung compliance is determined by elastic tissue
  • Elastic recoil allows for passive exhalation
  • Reduction in TLC, FVC, FEV1, vital capacity as we age
  • Elastic tissue important in holding terminal airways and alveoli open
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4
Q

What factors affect the lungs other than age?

A
  • Work exposure
  • Smoke exposure
  • Repeated infections
  • Chemical/toxin exposure
  • Chest infections become more common as we age - causes damage and scarring to lungs
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5
Q

How does reduced lung function affect older people?

A
  • Patients are at greater risk of respiratory infections
  • More likely to be acutely unwell
  • More likely to need hospitalisation
  • More likely to need oxygen/IV antibiotics
  • More prone to post operative complications
  • Sedating drugs more likely to cause respiratory problems
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6
Q

Which post-operative complications are elderly people more prone to due to reduced lung function?

A
  • Atelectasis
  • Pneumonia
  • Pulmonary embolism
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7
Q

How does ageing affect the cardiovascular system?

A
  • Blood vessels become more stiff as we age (especially arteries)
  • Elastic recoil is reduced so arteries are less expansile
  • Increases resistance to blood flow
  • Leads to hypertension
  • Increased cardiovascular work
  • Increased risk of left ventricular hypertrophy
  • Decreased left ventricular volume
  • Can lead to heart failure
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8
Q

How does left sided heart failure lead to right sided heart failure?

A
  • Blood backs up and pools in lungs
  • Right side of heart has to work harder against pressure
  • To get blood through lungs to be oxygenated
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9
Q

What are the risks of uncontrolled hypertension?

A
  • Increased risk of stroke
  • Increased risk of MI
  • CKD
  • Heart failure
  • AF - increases risk of stroke
  • Vascular disease e.g. abdominal aortic aneurysm
  • Damage to vision
  • Increased risk of vascular dementia
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10
Q

Outline the pathophysiology of atrial fibrillation

A
  • Hypertension causes increased stretch of the atria
  • Atrial stretch causes small areas of damage
  • New foci of electrical activity
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11
Q

What are the key features on an ECG which shows AF?

A
  • Wavy baseline
  • Absence of P wave
  • Irregularly irregular heart rate
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12
Q

How does age affect the renal system?

A
  • GFR decreases as we age
  • Structural changes
  • Atheromatous vascular disease
  • Reduced cardiac output
  • Lots of medications are renally excreted
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13
Q

Why is decreased kidney function a problem in elderly people?

A
  • A lot of medications are renally excreted e.g. morphine
  • Problem because older patients tend to be on multiple medications
  • Takes longer for them to excrete drugs
  • Can result in toxic effect
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14
Q

How can we avoid issues in elderly patients with renal problems?

A
  • Find out patients’ renal function before prescribing medications
  • Use alternative drugs
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15
Q

Which co-morbidities affect renal function?

A
  • Diabetes - leads to diabetic nephropathy and damage to microvascular structures due to hyperglycaemia
  • Hypertension - some antihypertensive medications are nephrotoxic (NSAIDS, ACEi)
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16
Q

What happens to bone as people age?

A
  • Bone density decreases
  • Gradual decline
  • Declines more quickly in women after menopause
17
Q

What happens to muscle as people age?

A
  • Muscle mass decreases
  • Multifactorial
  • Use it or lose it
18
Q

What happens to bone marrow as people age?

A
  • Bone marrow changes
  • Becomes less cellular and more fatty
  • Decreased cellular production
19
Q

What are the consequences of decreased bone density and muscle mass?

A
  • Increased risk of fracture (fragility fractures)
  • Increased falls risk
  • Decreased strength
  • Increased risk of trauma
  • Osteoporosis
20
Q

How does GI function change with age?

A
  • Liver function gradually reduces over time
  • Decreasing blood flow to liver
  • Decreased mass of functional liver cells
  • Slower transit through intestines - increased constipation
  • Decreased absorption e.g. of nutrients and medication
21
Q

Why is malnutrition an issue in the older person?

A
  • Good nutrition is essential for recovery from illness
  • More malnourished patients are, longer recovery takes
  • Wound healing particularly affected
  • Must screen all patients on admission
22
Q

How does malnutrition affect wound healing?

A
  • After surgery more likely to have wound breakdown or delayed healing
  • Increased risk of pressure ulcers
  • Pressure ulcers difficult to heal without nutrition
23
Q

How does ageing affect the neurological system?

A
  • Brain undergoes changes as we age
  • Some parts shrink - particularly areas related to learning and complex mental activities
  • Senescence of some cells
  • Reduced communication between neurones
  • Reduction in blood flow
  • Neuronal density reduces by almost 1/3 by the age of 80
24
Q

What are the different types of dementia?

A
  • Alzheimer’s
  • Vascular
  • Fronto-temporal
  • Lewy body
25
Q

How do we diagnose dementia?

A
  • Needs comprehensive assessment
  • History, examination, investigations
  • Determine the type of dementia and possible medication options
26
Q

How does ageing make management of older patients more complex?

A
  • Body systems are interdependent
  • Need to consider side effects and unintended consequences
  • Operations cause high physiological stress but elderly patients have low physiological reserve
  • Often multimorbid - can’t focus on one system
  • Needs a holistic approach
27
Q

How should we approach prescribing for elderly patients?

A
  • Can be particularly challenging
  • Have to balance proposed benefit with side effects
  • More likely to be on medications already - risk of interactions and unintended consequences/worse side effects
  • Reduced renal and liver excretion of drugs
28
Q

How can we get around reduced renal and liver excretion of drugs in elderly patients?

A
  • Dose reduction
  • Alternate medications
  • Close monitoring - titration and monitoring for effects
  • General rule is to start at a lower dose
29
Q

What questions should we ask before prescribing something?

A
  • Does something need prescribing?
  • Is there an alternative strategy?
  • If not what is the lowest possible dose?
  • Does that drug interact with any other medications?
  • If there is an interaction, which medication is most important?
  • Is there a more suitable alternative
30
Q

How can we make treatment a patient centred approach?

A
  • What does the patient want?
  • How can we achieve it?
  • What are the person’s beliefs?
  • Treating with dignity
  • Working in accordance with best interests
  • Is hospital the best place for your patient
  • What social needs does the patient have?
  • Loneliness is a big factor
31
Q

What does compassionate care allow patients to do?

A
  • Can think about planning for the future
  • Emergency healthcare plans
  • Reduce admissions to hospital
  • Allows clinicians to know what is important to patient
  • Resuscitation
  • Involve family/carers/friends