Ageing Flashcards

1
Q

What is the definition of frailty?

A

Distinctive health state related to ageing process

Multiple body systems gradually lose their in-built reserve

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2
Q

What tests can you carry out for frailty?

A
Rockwood Score
PRISMA-7 Questionnaire
Bournemouth Criteria
Electronic frailty index (eFI)
Timed up and go
Gait speed test
Grip strength
Self report by patient
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3
Q

What are the 5 frailty syndromes?

A
Delirium
Incontinence
Medication side effects
Falls
Immobility
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4
Q

What is a comprehensive geriatric assessment(CGA)?

A

Multidimensional. holistic assessment of older person

Leads to formulation of individual management plan

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5
Q

What are some physical components of a CGA?

A

Nutrition - eating well, constipation, swallowing
Pain - joint examination, alternative words e.g. aches
Sensory (vision/hear) - gross visual testing e.g no fingers
Continence - med reviews, storage/voiding problems
Lying/Standing BP
Bone health
Feet + footwear

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6
Q

When should lying/standing BP always be taken?

A

Patients >65 admitted to hospital with a fall

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7
Q

What is a psychological component of a CGA?

A

Mood

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8
Q

What mnemonic would you use to screen and assess continence?

A
Screen - 
U - Urgency
R - Regular trips
I - Incontinence/UTI/Indwelling catheter
N - Nocturia
E - Exercise/sneeze/cough leakage
Assess - 
D - Drugs/dementia
R - Rectal exam
I - Image bladder (PVRV)
P - Pv (vaginal examination)
S  - Send urine sample
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9
Q

What is stress urinary incontinence?

A

Involuntary passive loss of urine through stress exerted on the bladder due to pelvic floor muscle weakness

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10
Q

What are some common causes of stress urinary incontinence?

A
Childbirth
Prostate surgery
Obesity
Chronic cough
Previous pelvic surgery
Post-menopause
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11
Q

How would you manage stress urinary incontinence?

A
Conservative measures
Treat causes e.g. COPD, optimise lifestyle factors e.g. lose weight
Fluid management
Pelvic floor exercises
Bladder training
Surgery/Pessaries
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12
Q

What is urge urinary incontinence?

A

Sudden and strong desire to urinate, causes incontinence

AKA overactive bladder, detrusor instability

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13
Q

What factors can affect urge urinary incontinence?

A
Alcohol/food
Infection
Constipation
Age
Structural problems e.g. stones/cancer
Neurological disorders
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14
Q

How would you manage urge urinary incontinence?

A

Same as stress urinary incontinence
Bladder training, double voiding
Anticholinergics, Beta 3 agonists
Botox/nerve stimulator/surgery

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15
Q

What types of drugs can be used to help incontinence?

A

Muscarinic receptor antagonists (anticholinergic) e.g. oxybutinin, tolterodine, solifencacin
Beta 3 agonists e.g. mirabegron

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16
Q

What are some side effects of the drugs used to help incontinence?

A

Muscarinic receptor antagonists (anticholinergic) - falls, cognitive impairment, dry mouth, constipation
Beta 3 agonists - hypertension

17
Q

What are some features of incontinence caused by severe cognitive impairments?
Causes?

A

Loss of voluntary control over micturition/defecation
More reflex mediated/higher cortical function
Dementia + neurodegenerative conditions
Trauma/stroke/neurodisability

18
Q

How would you manage incontinence caused by severe cognitive impairments?

A

Modify any reversible causes
Toileting regime where possible - may incl bowel management
Supportive mit continence products, good skin + pressure area care

19
Q

What drugs can cause constipation?

A
Opioid analgesics
Supplements - Fe, Ca, Al
Beta blockers
Ca channel blockers
Anticholinergics
Antipsychotics
20
Q

Why are decarboxylase inhibitors administered with dopamine precursors?

A

So body doesn’t break down precursors before they reach brain.

21
Q

What area of the brain is targeted for deep brain stimulation?

A

Subthalamic nucleus (STN)

22
Q

What is a key hallmark of Alzheimer’s?

A

Medial temporal atrophy/hippocampus atrophy