Affective Disorders - Depression Flashcards

1
Q

What is a mood disorder?

A

Disorder of mental status/function where altered mood is the core feature

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2
Q

What mental health issues fall under “mood disorders”

A

Depression

Mania/Bipolar Disorder

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3
Q

Are mood disorders common?

A

Yes - commonest type of mental health disorder

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4
Q

Mood disorders can be primary or secondary to another issue, true of false?

A

True - mood disorders can arise as a consequence of other illnesses

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5
Q

What other disorder is mood disorders closely associated with?

A

Anxiety disorders

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6
Q

What are the 2 main classification systems for mood disorders?

A

ICD-10 - (International Classification of Disease 10th Edition - WHO)

DSM-5 (Diagnostic and Statistical Manual of Mental Disorders 5th Edition)

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7
Q

What is a syndrome?

A

A constellation of symptoms and signs

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8
Q

Is depression an emotion or is it a disorder?

A

Both, can be a normal emotion within the normal range of human emotion (sadness) which can range from mild to very severe in intensity

No clear consensus on when it becomes a disorder - matter of perspective usually

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9
Q

How do psychiatrists try and differentiate between a short bout of depression and a depressive disorder then?

A

Persistence of symptoms
Pervasiveness (prevalence) of symptoms
Degree of impairment
Presence of specific symptoms/signs

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10
Q

What 3 categories do depressive symptoms fall under?

A

Psychological
Physical
Social

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11
Q

What 2 subcategories fall under psychological symptoms?

A

Changes in mood

Changes in thought content

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12
Q

List examples of “changes in mood” symptoms.

A

Mood might change to include

  • Depression
  • Anxiety
  • Perplexity
  • Anhedonia
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13
Q

What is perplexity and anhedonia ?

A

Perplexity - inability to deal with or understand something

Anhedonia - loss of pleasure in normally pleasurable activities (disinterested in old hobbies)

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14
Q

What sort of variation can depression as symptom have?

A

Diurnal variation - occur or grow more severe every day at around the same time, usually the daytime

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15
Q

When is perplexity as symptom more likely to occur?

A

In post-childbirth illness

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16
Q

What sort of changes in thought can occur in the “changes in thought content” symptom subcategory

A

Patient can suffer from

  • Guilt
  • Hopelessness
  • Worthlessness
  • Delusions and hallucinations if severe
  • Also suffer from neurotic symptoms such as hypochondria, agoraphobia, obsessions/compulsions and panic attacks
17
Q

What physical symptoms can depression have?

A
Low energy --> fatigue 
Low appetite --> weight loss
Affected sleep
Libido
Constipation
Pain

Changes in psycho-motor functioning such as agitation (restless over activity) or retardation (slowing of motor responses such a speech)

18
Q

What social symptoms happen in depression?

A
Withdrawal from social situations
Apathy towards others
Irritability towards others
Loss of concentration, memory 
Loss of interests (anhedonia ?)
19
Q

What is stupor?

A

A state of extreme retardation in which consciousness is intact. The patient stops moving, speaking, eating and drinking. On recovery can describe clearly events which occurred whilst stuporose

20
Q

Depression according to the ICD-10 will…

A
  • Last for 10 weeks
  • Will not result hypomanic/manic episodes
  • Can not be attributable to psychoactive substance abuse or organic mental disorder (causes by injury or disease)
21
Q

If patient has depression with psychotic symptoms, how is it diagnosed?

A

MUST rule out other psychotic illnesses like schizophrenia first before classifying it as “severe depression with psychotic symptoms”

22
Q

What are some ICD-10 criteria’s for Somatic Syndrome

A

Widespread anhedonia
Lack of an emotional reaction to events which should produce one
Depression worse in the morning
Waking up about 2 hours before normal
Loss of appetite and weight loss (5% in one month)
Loss of libido
Evidence of retardation or psycho-motor agitation

23
Q

What is the ICD-10 criteria list for MILD, MODERATE and SEVERE depression?

A

MAJOR

  • Depressed mood all day, almost everyday for past 2 weeks with no cause
  • Anhedonia
  • Low energy

MINOR

  • Low self-esteem or confidence
  • Low concentration
  • Unreasonable feelings of guilt
  • Suicidal thoughts
  • Agitation or retardation
  • Disturbed sleep
  • Change in appetite

Mild - At least 2 major with additional minors making 4 at least

Moderate - At least 2 majors with additional minors making 6 total at least

Severe - All 3 majors with additional minors making 8 total (hateful 8)

24
Q

What % of women develop major depressive disorder after giving birth and within what time frame?

A

10% within 3 to 6 months

25
What % of women experience "blues" post childbirth and within what time frame?
75% within 2 weeks
26
There is an increased risk of BLANK admission in the BLANK days following childbirth.
Psychiatric admission | 30 days
27
Is post-natal depression a hormonal thing?
Not shown to be
28
List some differential diagnosis' for depression?
``` Normal reaction to a life event Seasonal affective disorder Bipolar Stroke, tumour, dementia Endocrine diseases - hypothyroid, hyperparathyroid, addisons Drug abuse ```
29
What pharmaceutical managements are there of depression?
SSRIs SNRIs Tricylic antidepressants (TCAs) Monamine Oxidase Inhibitors (MAOIs)
30
What psychological managements are there of depression?
CBT Mindfulness based therapies Family therapy
31
What physical managements are there of depression?
Electroconvulsive therapy (ECT) Psycho-surgery Deep brain stimulation Vagus nerve stimulation
32
How ling does a typical episode of MDD last (major depressive disorder)
Typical ep. lasts 4 to 6 months
33
How my % of people have further episodes of mdd?
80%
34
WHAT % OF PEOPLE WERE RECOVERED BY 26 WEEKS?
54%
35
What % of people die by suicide in MDD?
15%
36
What % of people fail to recover in MDD?
12%
37
What is the ratio for prevalence within gender?
2:1 towards females