aetiology and pathogenesis Flashcards
describe gingival health
clearly defines , scalloped, knife edge gingival margin that is pink in colour
abscence of bleeding on probing ( less than 10% of sites) and no probe depths more than 3mm
gingivitis
result of plaque accumulation
redness and swelling of gingiva with bleeding upon probing/brushing ,
definition - pocket depth no more than 3mm
no attachment or bone loss, bleeding on probing at less than 30% but mre than 10% of sites, clinical changes are reversible!!
periodontitis
loss of periodontal attachment and potential alveolar bone loss
pocket depths of more than 3mm
irreversible!
false pocket
sulcular epithelium proliferates in response to plaque an gingiva enlarges - probe will disappear but not actually any attachment loss
true pocket
sulcular epithelium migrates apically, plaque then accumulates on the root and apical migration continues. this is couples with inflammation
what is the normal distance of alveolar bone from the cemento-enamel junction
1-2mm
can be seen using radiographs
horizontal bone loss
bone lost in fairly consistent and flattish pattern across teeth
vertical bone loss
bone loss more extensive on one side than the other
what does the pattern of bone loss depend upon
the amount of bone between teeth
most apical point of plaque has a 2mm destruction zone , if there is lots of bone between teeth a vertical pattern will be seen, if not a lot of bone a horizontal pattern
furcation bone loss
bone loss in furcations , in severe bone loss probe can go right through furcations
keystone pathogen of periodontitis
p.gingivalis
what attachment loss is considered rapid progression
more than or equal to 2mm over 5 years
describe the differences in microbial balance and host immune responses between health, gingivitis and periodontitis
health - symbiosis and proportionate immune response
gingivitis - dysbiosis and proportionate immune response
periodontitis - dysbiosis and disproportionate immune response resulting in soft and hard tissue damage
what enzymes are largely responsible for soft tissue destruction (matrix degradation) and where do they come from
MMPs (matrixmetalloproteinases)
these are degradative enzymes released by host inflammatory cells e.g macrophages, lymphocytes
what causes hard tissue/ bone destruction
increased action of osteoclasts as excessive immune response is assosciated with increased RANKL