aetiology and pathogenesis Flashcards

1
Q

describe gingival health

A

clearly defines , scalloped, knife edge gingival margin that is pink in colour
abscence of bleeding on probing ( less than 10% of sites) and no probe depths more than 3mm

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2
Q

gingivitis

A

result of plaque accumulation
redness and swelling of gingiva with bleeding upon probing/brushing ,
definition - pocket depth no more than 3mm
no attachment or bone loss, bleeding on probing at less than 30% but mre than 10% of sites, clinical changes are reversible!!

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3
Q

periodontitis

A

loss of periodontal attachment and potential alveolar bone loss
pocket depths of more than 3mm
irreversible!

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4
Q

false pocket

A

sulcular epithelium proliferates in response to plaque an gingiva enlarges - probe will disappear but not actually any attachment loss

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5
Q

true pocket

A

sulcular epithelium migrates apically, plaque then accumulates on the root and apical migration continues. this is couples with inflammation

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6
Q

what is the normal distance of alveolar bone from the cemento-enamel junction

A

1-2mm

can be seen using radiographs

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7
Q

horizontal bone loss

A

bone lost in fairly consistent and flattish pattern across teeth

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8
Q

vertical bone loss

A

bone loss more extensive on one side than the other

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9
Q

what does the pattern of bone loss depend upon

A

the amount of bone between teeth
most apical point of plaque has a 2mm destruction zone , if there is lots of bone between teeth a vertical pattern will be seen, if not a lot of bone a horizontal pattern

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10
Q

furcation bone loss

A

bone loss in furcations , in severe bone loss probe can go right through furcations

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11
Q

keystone pathogen of periodontitis

A

p.gingivalis

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12
Q

what attachment loss is considered rapid progression

A

more than or equal to 2mm over 5 years

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13
Q

describe the differences in microbial balance and host immune responses between health, gingivitis and periodontitis

A

health - symbiosis and proportionate immune response
gingivitis - dysbiosis and proportionate immune response
periodontitis - dysbiosis and disproportionate immune response resulting in soft and hard tissue damage

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14
Q

what enzymes are largely responsible for soft tissue destruction (matrix degradation) and where do they come from

A

MMPs (matrixmetalloproteinases)

these are degradative enzymes released by host inflammatory cells e.g macrophages, lymphocytes

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15
Q

what causes hard tissue/ bone destruction

A

increased action of osteoclasts as excessive immune response is assosciated with increased RANKL

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16
Q

why does smoking increase your risk of periodontitis

A

it impairs aspects of the immune response