Aerobic gram- negative cocci Flashcards

1
Q

Neisseria gonorrhoeae

A

G- diplococci, outer surface w. multi virulence factors/ags
diagnosis by nucleic acid amplification
resistant to most Abios, now use ceftriaxone

D: gonorrhea- venereal disease, disseminated infections- spread to skin or joints, ophthalmia neonatorum-ocular infection acquired at birth

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2
Q

Neisseria meningitidis

A

G- diplococci, antiphago group-specific capsular polysacch, endotoxin (LPS) produces inflammation
Vaccine: capsular polysachh (CPS), CPS protein conjugate, recombinant protein

D: meningitis- young adults, meningococcemia- disseminated infection with petechia and purpura, repeated attacks in patients with def. in terminal complement proteins

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