AED SEs Flashcards
1
Q
Valproate key SE
A
- Weight gain
- Embryopathy/teratogenic
- Hair loss
- Pancreatitis
- Hepatic failure
- Lamotrogine interaction
NOT used under 3 before metabolic Ix - risk fatal liver toxicity secondary to undiagnosed metabolic condition
2
Q
Carbamazepine key SE
A
- HLA-B* 15:02
- L - Leukopenia
- A -Contraindicated in absence/myoclonic jerks
- S - SJS and rash
H - Hyponatremia
3
Q
Phenobarbitone key SE
A
Rash
4
Q
Clonazepam key SE
A
- Increased secretions
5
Q
Phenytoin key SE
A
- G - Gum hypertrophy and hirsuitism
- R - Rash
- O - osteoporosis
S - Serum sickness
6
Q
Lamotrogine key SE
A
- Hypersens lamb
- Rash SJS
- Severe hypersensitvity
Valproate interaction
7
Q
Vigabatrin key SE
A
- Bat shit crazy
- Weight gain
- Retinopathy
Psychosis
8
Q
Topiramate key SE
A
- Nephrolithiasis and acidosis
- Weight loss
Glaucoma
9
Q
Oxycarbazepine key SE
A
Hyponatremia