AED SEs Flashcards

1
Q

Valproate key SE

A
  • Weight gain
  • Embryopathy/teratogenic
  • Hair loss
  • Pancreatitis
  • Hepatic failure
  • Lamotrogine interaction
    NOT used under 3 before metabolic Ix - risk fatal liver toxicity secondary to undiagnosed metabolic condition
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2
Q

Carbamazepine key SE

A
  • HLA-B* 15:02
  • L - Leukopenia
  • A -Contraindicated in absence/myoclonic jerks
  • S - SJS and rash
    H - Hyponatremia
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3
Q

Phenobarbitone key SE

A

Rash

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4
Q

Clonazepam key SE

A
  • Increased secretions
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5
Q

Phenytoin key SE

A
  • G - Gum hypertrophy and hirsuitism
  • R - Rash
  • O - osteoporosis
    S - Serum sickness
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6
Q

Lamotrogine key SE

A
  • Hypersens lamb
  • Rash SJS
  • Severe hypersensitvity
    Valproate interaction
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7
Q

Vigabatrin key SE

A
  • Bat shit crazy
  • Weight gain
  • Retinopathy
    Psychosis
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8
Q

Topiramate key SE

A
  • Nephrolithiasis and acidosis
  • Weight loss
    Glaucoma
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9
Q

Oxycarbazepine key SE

A

Hyponatremia

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