AED half lives Flashcards
1
Q
Acetazolamide
A
12-14 hours
2
Q
Carbamazepine
A
10-20 hrs (after autoinduction); 24-60hrs (initial)
3
Q
Clobazam
A
24-48 hours (N-desmethylclobazam - 3-4 days)
4
Q
Clonazepam
A
20 hours (children); 20-60 hrs (adults)
5
Q
Eslicarbazepine
A
12-20 hours
6
Q
Ethosuximide
A
30-40 hours
7
Q
Ezogabine
A
8 hours
8
Q
Felbamate
A
20 hours
9
Q
Gabapentin
A
5-8 hours
10
Q
Lacosamide
A
13 hours
11
Q
Lamotrigine
A
25 hours
12
Q
Levetiracetam
A
6-8 hours
13
Q
Oxcarbazepine
A
8-12 hours (including derivative; parent drug = 2hrs)
14
Q
Perampanel
A
100 hours (4 days)
15
Q
Phenobarbital
A
2-7 days
16
Q
Phenytoin
A
10-30 hours
17
Q
Pregabalin
A
6-10 hours
18
Q
Tiagabine
A
7-9 hours
19
Q
Topiramate
A
20 -24 hours
20
Q
Valproate
A
6-12 hours
21
Q
Vigabatrin
A
5-8 hours (increases with age of pt)
22
Q
Zonisimide
A
60 hours
23
Q
Stiripentol
A
8hrs (children); 24hrs (adult)
24
Q
Cannabidiol
A
50-60hrs
