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Antibiotics > Adverse Effects > Flashcards

Adverse Effects Flashcards

0
Q

Ampicillin

A

Acute interstitial nephritis, rash with acute EBV infection

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1
Q

Penicillins

A

Allergy, hemolysis, diarrhea, seizures

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2
Q

Piperacillin

A

interstitial nephritis, hepatitis, diarrhea, seizures

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3
Q

Nafcillin

A

Hypersensitivity

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4
Q

Ampicillin/sulbactam combinations

A

hypersensitivity, interstitial nephritis

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5
Q

Piperacillin/tazobactam

A

hypersensitivity, interstitial nephritis, seizures

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6
Q

1st gen cephalosporins

A

cross sensitivity with penicillin allergy

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7
Q

2nd gen cephalosporins

A

cross sensitivity with penicillin allergy but milder than 1st gen

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8
Q

3rd gen cephalosporins

A

cross sensitivity with penicillin allergy but milder than 2nd gen, elevated bilirubin, gallstones

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9
Q

Carbapenems

A

nausea, vomiting, diarrhea, seizures, cross sensitivity with penicillin allergy

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10
Q

Aztreonam

A

no cross sensitivity with beta lactam allergy

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11
Q

vancomycin

A

ototoxicity, fever, chills, red man syndrome, leukopenia

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12
Q

Fluoroquinolones

A

tendon rupture, photosensitivity, QT prolongation, rash, CNS; not for pregnant women or children <10

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13
Q

Macrolides

A

GI discomfort, ototoxicity, QT prolongation

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14
Q

Clindamycin

A

C. difficile colitis, rash

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15
Q

Metronidazole

A

dark/rusty colored urine

16
Q

Tetracycline and similar

A

GI discomfort, bone deposition, photosensitivity; not indicated for pregnant women and children

17
Q

Tigecycline

A

photosensitivity, hepatitis

18
Q

Aminoglycosides

A

nephrotoxicity, ototoxicity

19
Q

daptomycin

A

elevated creatinine phosphatase

20
Q

linezolid

A

reversible myelosuppression, thrombocytopenia, serotonin syndrome

21
Q

Folate antagonists

A

SJS, rash, fever, leukopenia, hepatitis, thrombocytopenia, photosensitivity

22
Q

Rifampin

A

hepatotoxicity

23
Q

Polymyxin

A

renal and neurotoxicity

Antibiotics (2 decks)

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