Adverse Drug Reactions

Question 1

What are the possible adverse reactions associated with gentamycin & vancomycin?

Answer 1

Nephrotoxicity, ototoxicity

Question 2

What are the possible adverse reactions associated with broad spectrum antibiotics such as cephalosporins/ ciprofloxacin?

Answer 2

C.diff colitis

Question 3

What are the possible adverse reactions associated with ACE inhibitors eg lisinopril?

Answer 3

Hypotension, electrolyte abnormalities, AKI, dry cough

Question 4

What are the possible adverse reactions associated with beta blockers eg bisoprolol?

Answer 4

Hypotension, bradycardia, wheeze in asthmatics, worsens acute HF but helps chronic HF

Question 5

What are the possible adverse reactions associated with diuretics eg furosemide?

Answer 5

Hypotension, electrolyte abnormalities, AKI

Question 6

What are the possible adverse reactions associated with CCBs eg diltiazem?

Question 7

Which diuretic is associated with gynaecomastia?

Answer 7

Spironolactone

Question 8

What are the most common medications associated with hyponatraemia?

Answer 8

Diuretics - particularly thiazides
SSRIs
Antipsychotics
Carbamazepine

Question 9

What are the most common medications associated with hypercalcaemia?

Answer 9

Thiazide diuretics
Lithium
Vitamin D
Vitamin A
Calcium co-prescribed with antacids

Question 10

What are the most common medications associated with hyperkalaemia?

Answer 10

Potassium sparing diuretics eg spironolactone
ACE inhib
ARBs
Ciclosporin
Heparin

Question 11

What are the most common medications associated with hypocalcaemia?

Answer 11

Bisphosphonates
Cisplatin
Anti-epileptics
Aminoglycoside
PPIs