Advanced Principles Exams Flashcards
Maternal CO increases by?
50% (most correct answer 40%)
All of the following increased during pregnancy EXCEPT?
SVR
Mother becomes hypotension in supine position, what do you do?
Turn patient to right side with towel roll
What increases risk of hypoxia during pregnancy? Pick 2
Decreased FRC INCREASED A-a gradient
Which is true during pregnancy? Pick 3
Decreased FRC Decreased MAC for GA Decreased PCO2
Which structure identifies the cytotrophoblast? Which structure identifies the syncytiotrophoblast?
look at image [ctotrophoblast]
Which structure identifies the umbilical arteries? Which structure identifies the umbilical veins? What structure identities the ductus arteriosus?
insert image [fetal circulation]
Which affects drug passage through the placental barrier?
Molecular weight, lipid solubility, ionization of drug
Normal FHR is 130-80. True or False
False (normal is 110/120-160)
Oxygenated blood is brought through?
Umbilical vein
Deoxygenated blood is brought to the placental through?
Umbilical arteries
What is best used to prevent DVT during pregnancy?
Compression stockings
Which lab is suggested of NTD (ex: Spina Bifida)?
INCREASED alpha fetoprotein
Which lab is suggested for Downs Syndrome Trisomy 21?
DECREASED alpha fetoprotein
Which is true of first stage labor? Pick 2
Level of spinal needed is T10-L1 Visceral pain is caused by uterine contraction
Which is true of second stage labor? Pick 3
Pain is through pudendal nerves
Somatic pain is due to stretching of vagina
Level of spinal needed for anesthesia is S2-S4
What describes the birth defect causing the backbone and spinal canal not to properly fuse?
myelomeningocele
What is true about diaphragmatic hernia (choose 2)
-occurs when the diaphragm, the muscle that separates the chest from the abdomen, fails to close during prenatal development -Is a life threatening illness that prevents lung development
What is true about anesthetic management for fetal surgery?
2 patients and Maternal safety is paramount
Absent or minimal variability indicates that there is a compromise to fetal health. True or false?
TRUE
Which correlates with fetal head compression?
Early Decelerations
41 weeks describes what term?
LATE Term
Ultrasonography is recommended for all pregnancies because it? Pick 3
Determines gestational age Determines placental position Determines structural abnormalities
Lepold’s Manuever used to elevate a 12 week fetus, the fundal height should be measuring at?
Pelvic brim
what is true of Aspirin use during the 3rd trimester? Pick 3
Oligohydraminios
Renal injury
Intrauterine constriction of the ductus arteriosus
Which of the following is true regarding pregnancy and anticoagulants?
-Pregnant women have 5x the normal risk for venous thromboembolism -LMWH is less likely to cause HIT -Unfractionated heparin is easier to reverse
Which weight significantly increased newborn and maternal morbidity?
4500 - 4999
Major physiologic changes during pregnancy alter drug disposition by:
-Decrease in intestinal motility -Reduced FRC -Increased minute ventilation increases pulmonary uptake of inhalation anesthetics
Nonstress test is less useful in the very preterm fetus. True or false?
True
The most common indication for 2nd trimester amniocentesis is for?
Cytogenetic analysis of fetal cells
Most Common Medications Taken During Pregnancy? Choose 3
Antiemetics Antibiotics Analgesics
Drugs taken with long term CNS effects? Choose 3
Antidepressants Anticonvulsants Antipsychotics
Parasympathetic outflow by means of the vagus nerve increases the FHR, true or false?
False - (Parasympathetic outflow decreases FHR)
An example of physiological changes of pregnancy that may alter drug disposition is?
Placental transfer
Caffeine is not shown to produce teratogenic effects. True or false?
true
Most anesthetic drugs have been shown to be teratogenic? True or false?
False
The Contraction Stress Test assesses fetal heart rate response to uterine activity by? (2)
Maternal exercise monitoring
Nipple stimulation
Oxytocin Administration
Using vibratory stimulation
Nipple stimulation Oxytocin Administration
Which is true of the second stage of labor? (choose 3)
Somatic pain caused by stretching of vagina, perineum, & vulva by descent of fetus • Pain is through the Pudendal nerve • Level of spinal anesthesia is needed for S2-S4
Obesity is defined as a BMI of ____ •
>30 kg/m2
Which of the following is true regarding anticoagulants in pregnancy? (Choose 3)
• LMWH is preferred • LMWH is less likely to cause HIT • Shorter half-life of UFH means it’s easier to reverse
Which of the following is true regarding anticoagulants in pregnancy? (choose 2)
• Warfarin is a vit K antagonist and can cause embryopathy, esp. in 1st trimester • Rivaroxaban and thrombin inhibitor Dabigatran (Pradaxa) cross the placenta and are NOT recommended
Which of the following is true regarding transfer of drugs in breast milk? (choose 4)
• Benzos are considered safe • NSAIDs are safe when breastfeeding • Acetaminophen is the standard analgesic • Anesthetic drugs are considered SAFE
Fetal growth restriction is associated with which adverse perinatal outcomes? (choose 3)
• Intrauterine demise • Neonatal morbidity and mortality • Cognitive delay in childhood
Fetal risk Factors for high risk pregancy:
a. Fetal growth restriction b. Multiparity c. Previous unexplained still birth d. Singledom pregnancy
Example of direct pharmacologic effects would be:
Placental transfer
Most common medications taken during pregnancy (choose 3)
Antiemetics Analgesics Antibiotics
At least 10% of pregnant women are taking these medications that can cause long term CNS effects (choose 3)
Antipsychotics Anticonvulsants Antidepressants
Things that affect absorption and uptake of drugs during pregnancy include all of the following EXCEPT:
Oral aborption and bioavailability is majorly affected by pregnancy o Oral absorption and bioavailability is NOT usually affected by pregnancy
- Intestinal motility decreases
- Reduced FRC
- Increased minute ventilation increases pulmonary uptake of inhalational anesthetic agenst
True or false? No anesthetic agents have been found to be teratogenic.
True
Which of the following is TRUE? (choose 2)
• Acetaminophen is the preferred mild analgesic and antipyretic during pregnancy • NSAIDs have been associated with increased risk for some birth defects
True of False? Heparins do NOT cross the placenta
TRUE
Is caffeine teratogenic in fetus?
No
Myleomeningocele is
A birth defect in which the backbone and spinal canal do not close before birth
Parasympathetic outflow by means of the vagus nerve will cause ____
Decreased FHR
True or false? You have two patients when dealing with OB and Mom is first priority.
True
Giving birth at 41 weeks is considered ____
Late term
Ultrasound is recommended for all pregnancies for its ability to: (choose 3)
• Accurately determine gestational age • Determine placental location • Screen for fetal structural abnormalities in the second trimester
At approximately 12 weeks where can the uterus be palpated?
Above the pelvic brim
Fetal growth restriction is associated with which adverse perinatal outcomes? (choose 3)
• Intrauterine demise • Neonatal morbidity and mortality • Cognitive delay in childhood
Newborn and maternal morbidity increases with fetal birth weight between _____
4500-4999 g
True or false? Non-stress test is useful in the very pre-term fetus
FALSE
Contraction stress test is done by: (choose 2)
• Administration of IV Oxytocin • Nipple stimulation
The most common indication for 2nd trimester amniocentesis is _____
Cytogenetic analysis of fetal cells
Fetal conditions that may result in Fetal Growth Restriction? Don’t remember the answer to this one
• CP d/t hypoxia • Congenital heart disease • Teratogenic exposure • Structural malformation
- All of the following are true of multiple gestation(choose 3): It was choose 3 true statements; i didn’t have an idea where this information came from
a. Twin A is more depressed and asphyxiated?
- Which of the following is least indicated for treatment of BP 190/110?
a. Esmolol
hydralazine, labetalol, and nifedipine are all effective antihypertensive in these patients. refractory htn may necessitate continous infusion of ntg, SNP, and fenoldopam for short term therapy.
- Which of the following is not a S&S of magnesium toxicity?
a. Hypertension
- What conditions are associated with placenta PREVIA:
a. Prev C/S; Advanced maternal age; Smoking hx
conditions associated with placenta previa include multiparity, advanced maternal age, smoking hx, male fetus, previous c/s or other uterine surgery, and previous placenta previa.
- Complications of PIH/Preclampsia:
a. Pulm. edema; CVA; Placenta Abruption
- What ECG changes are seen with administration of Ondasetron, Droperidol, and Oxytocin?
a. Prolonged QT Interval (Two answer choices, this answer appeared twice)
- Afr. Am. patient came in with elevated BP (161/110 and 170s), visual disturbances, RUQ pain, headache (Missing some S&S): What is the likely diagnosis?
a. Pre-eclampsia (Question appeared twice; no Seizure )
- Most common nerve injured during abdominal hysterectomy?
a. Femoral
- Two most common postpartum HA?
a. Migraine and Tension
- Headache that radiates to neck and shoulder without a previous dural puncture
a. Musculoskeletal
- Patient 23 weeks pregnant comes in with preterm labor. What medication should be given?
a. Beta stimulant