Advanced MSK Exam Flashcards
What is included if the injury is Articular?
INERT tissue damage
(doesn’t move)
* Ligament
* Cartilage
* Bone
* Connective tissue
* Monoarticular
* Polyarticular
What is included if the injury is Non-Articular?
Dynamic tissue damage (moves)
* Tendons
* Muscles
* Localized
* Limited, focal
* Widespread
* Regional, systemic
Traumatic vs. Atraumatic
- Traumatic = acute, defined moment
- Atraumatic = chronic, insidious onset
Referred vs. radiating pain
Referred
* Pain felt in a part of the body remote from source of the pain
* Left shoulder pain with myocardial infarction
Radiating pain
* Usually neuropathic
* Felt along a particular nerve innervation
* Ulnar nerve trauma (funny bone)
Nociceptive pain
Stimulation of pain receptors
(Nociceptors)
stabbing, stinging, sharp
* Traumatic injury
* Burns
* Infection
* Tissue degeneration
Somatic pain
Constant, achy pain:
* Cutaneous - Well localized in the superficial tissues
* Deep - Poorly localized the deeper tissues
Bone fracture
* Incision in the skin
* Arthritis
* Peripheral Vascular Disease (PAD)
Visceral Pain
Poorly localized, deep & diffuse pain sensation emanating
from internal organs or cavity linings
* Described as cramping
* Distention of a hollow viscous (ie bladder, bowel)
Neuropathic Pain
Poorly localized sensation of pain resulting from injury nerves
in the CNS or PNS.
* Described as shooting, electric shock, or burning
* Diabetic Neuropathy
* Post-herpetic neuralgia
* Nerve compression
Phantom Pain
Sensation of pain in a region of the extremity now amputated.
* Experienced by 30-81% of amputees, often described as:
* Aching, cramping, burning, tearing, squeezing
Calor
↑ heat = vascular permeability/blood flow
Rubor
redness = vascular permeability/blood flow
Tumor
swelling = accumulation of exudate
(↑ vascular permeability, 2° ischemic injury, cellular lysis)
Dolor
pain = chemical mediators of inflammation
Inflammatory Arthritides
Rheumatoid arthritis (RA)
Seronegative
spondyloarthropathies
Crystalline deposition
diseases (ex/ gout)
Septic arthritis
Bursitis
Tenosynovitis
Trauma
Laboratory markers for inflammatory conditions
Erythrocyte Sedimentation Rate (ESR)
C-Reactive Protein (CRP)*
Rheumatoid Factor (RF) (autoantibody)
Cyclic Citrullinated Peptide Antibody, IgG (CCP)
Erythrocyte Sedimentation Rate (ESR)
Blood in a tall, thin tube
Inflammation causes cells to
clump
more dense than individual
cells
settle to the bottom
more quickly
Non-specific test used to
detect inflammation
C-Reactive Protein (CRP)
Acute phase
inflammation
What is Rheumatoid Factor (RF)?
- Aids in the workup of suspected RA or
undifferentiated inflammatory arthritides - Order with Cyclic Citrullinated Peptide
Antibody, IgG - ↑specificity
- ↑sensitivity
What is Cyclic Citrullinated Peptide
Antibody, IgG (CCP)?
(+) ~69-83% of patients with RA
* Together with (+) RF
* Specificity = 93-95% for RA
Non-inflammatory Musculoskeletal Conditions
Painful conditions that, typically, are NOT accompanied by
the OVERT cardinal signs of inflammation:
* Osteoarthritis (OA)
* Neoplasm
* Pain amplification
* Fibromyalgia