Advanced | Intraoperative or Perioperative Disease States Flashcards

1
Q

An ASA 1 28 year old male attends for inguinal hernia repair under general anaesthesia. He is administered propofol 180mg morphine 8mg rocuronium 50mg cephazolin 2g. Post induction he develops an erythematous rash on his chest and arms, swelling of his lips and face, tachycardia and severe hypotension. Preliminary blood results revealed:

Tryptase 321 mcg/L at 1 hour
Tryptase 58 mcg/L at 3 hours
IgE is normal
Morphine RAST is elevated

The most likely diagnosis is:

A. IgE mediated morphine allergy

B. IgE mediated rocuronium allergy

C. Morphine induced histamine
release

D. IgE mediated cefazolin allergy

E. Mastocytosis

A

B. IgE mediated rocuronium allergy

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