Advanced developmental Flashcards

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1
Q

Where does the UK rank in a measure of pressure on families?

A

The UK ranks 24th out of 27 European countries in a composite measure of pressure on families

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2
Q

What is the lifecourse approach in developmental psychology/medicine?

A

How early events affect later disease patterns

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3
Q

Evidence for the lifecourse approach presented by Barker et al in the 1980s?

A

Identified that under-nutrition caused changes in the foetus in later life that were linked to coronary heart disease.

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4
Q

The development of working memory, attention and inhibitory control problems can be biologically explained how?

A

Emotional insults that affect the development of the pre-frontal cortex that begins in infancy and continues into adulthood.

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5
Q

What is normative stress and toxic stress, how do they both contribute to child development?

A

Normative stress is part of normal development and helps the child develop coping mechanisms.

Toxic stress however is an insult that occurs with protective factors (such as positive attachment with an adult)

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6
Q

How has the scientific thought process been formalised?

A

Used to be:

Observations
Suppositions
Questions

Now:

Facts
Hypothesis
Theories

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7
Q

Definition of a fact?

A

A repeatable careful observation, or measurement

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8
Q

Different methods for answering different types of questions in cross-sectional research?

A
  1. Questions about population stats e.g. stats for age

Within group summary - How does age relate to performance

Between group comparison - how do boys compare to girls at certain ages

USE Multi-level modelling

  1. Questions about what factors influence measures e.g. attention and exercise

Within group - how does exercise influence a childs attention

Between group - is attention a function of BMI

USE correlational

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9
Q

Definition of a theory?

A

A well substantiated useful explanation based on knowledge that has repeatedly been conformed and not yet falsified

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10
Q

When would you want to use an individual growth model/multilevel model for change?

A

Longitudinal - Questions about systematic change over time

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11
Q

When would you want to use discrete or continuous time analyses?

A

Longitudinal - Questions about whether and when events occur.

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12
Q

What is a conjectural account?

A

Not a full scientific theory - has stood up to repeated attempts of falsification

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13
Q

Basically; what does the second law of thermodynamics say?

A

Entropy is always increasing, function of number of microstates that give way to macrostates

Pack of cards has a ridiculous number of orders

If you keep shuffling a pack of cards it keeps getting more and more disordered

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14
Q

What happens to entropy in life?

A

Things become MORE ordered, entropy DECREASES.

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15
Q

What is information theory?

A

There is free energy - surprise (entropy?)

The job of the human nervous system is to minimise free energy - to make better predictions.

May link and explain lots of brain theories, like baysian theory and neural darwinism

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16
Q

What is dynamical systems theory? How does this relate to development

A

Relates to information theory

Idea that systems change over time.

Development is:
Step-by-step - don’t know where it will end up. Baby steps.
Non-linear - messy, things happen at different times, not nice gradual progression.
Continuous in time - may develop things then stop and come back to.
Soft assembled
Multi-determined

Should track observable behaviours over time and describe how elements interact in short and long term - have to take a step back and look at things in context.

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17
Q

What is emmotropia, myopia and hypermetropia?

A

Emmotropia - normal

Myopia - eye is too large (keeps growing) - short sightedness

Hypermetropia - Eye is too small (doesn’t start growing when it should) - long sightedness

`this process appears to be under neural control.

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18
Q

What is Amblyopia, what causes it - how does this process happen? What is the critical period?

A

When the cortical cells don’t receive adequate stimulation. The critical period is when the system has plasticity and will develop normal vision.

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19
Q

What are the use for motor milestones for development in children?

A

The key acquisition of motor skills in a fairly ordered pattern. some skills require others to be acquired first.

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20
Q

Development of basic manipulative skill over the first 12 months?

A

7-15 days - visually elicited reaching

3-4months - visually controlled reaching

5-6 months - closed loop visual control

12 months - maturish grasping behaviour

This however is refined until 6-8years

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21
Q

Progression of writing and drawing? how fast does this progress

A

Holding palmar 8 months

Pincer - 18 months

Simple lines - 2 years

draw/paint - 4 years

painting and writing 6-8 years

Moderately fast progression

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22
Q

What types of skills progress slowly?

A

Dressing grooming - 2-4 years
Construction skills - 3-5

Bimanual skills:

  • Transfer 6-7 years
  • Functional assymetry - 5-12
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23
Q

What is an example of developmental abnormality that backs up embodied cognition?

A

Embodied cognition holds that the nature of the human body is largely determined by form of the human body.

Children with cerebral palsy for example will typically have lesser mathematical ability than children without.

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24
Q

Why are the figures of developmental disorder increasing?

A

We are good at keeping kids alive

Large migration

Increasingly unhealthy environments - obesity epidemic

Austerity cuts - Jeremy cunt.

Massive increases in inequality - inequality is bad for everyone, including those who are well-off

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25
Q

Issues with birth? Conditions?

A

large object going through small hole - cerebral insults - cerebral palsy, Developmental coordination disorder.

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26
Q

Why does trisomy in the 21st chromosome not result in abortion?

A

small enough not to make that much of a difference.

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27
Q

Van Bergen et al’s model’s approach to assortive mating?

A

Assortive mating suggests that parents with similar traits are more likely to mate.

This affects the children through environmental and genetic factors.

For example a parent with bad reading may mate with a individual also with bad reading, and they may not read to their child.

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28
Q

Description of Pennington’s cascade model?

A

from bottom up,

Genes
Neural systems
Sensorimotor processes 
Higher order cognition
Behaviours
Diagnostic constructs e.g. dyslexia

Each level has a number of components that interact with each other, i.e. one gene may influence one component and then that will affect others - it is such a complex system that we cant predict how one change at one level will affect other levels and the eventual diagnostic construct.

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29
Q

What is a construct, how does this affect diagnosis?

A

A construct is an explanatory variable that is not directly observable.

Diagnoses are constructs with ‘fuzzy’ lines - they are categories of convenience, but the diagnoses are complex and not all the same.

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30
Q

WHO definition of disibility?

A

Bodily structures and impairments may not cause disability

Participation in activities is what defines disability

It is subjective and personal

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31
Q

What does a 22q11.2 deletion tell us about genetic/environment interplay?

A

Significantly increases risk of developing developmental abnormality - but not guaranteed and many different disorders, tells us there are a lot of environmental affects.

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32
Q

Dietary exposures that affect development?

A

Iodine - we know none is bad, not sure about suboptimal, being investigated at the moment

Acrylamides - processed food, have a negative impact on developing food - equivalent to smoking

Alcohol - binge drinking is bad

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33
Q

Ethnic differences of smoking and drinking (in bradford)?

A

15% avg. smoke

  • 33% white British
  • 3% south asian

20% drinking avg. during pregnancy

  • 43% white British
  • 0.2 South asian
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34
Q

WHO framework for considering social determinants on health?

A

Structural determinants:

  • Socioeconomical and political context
  • SES

Intermediary determinants:

  • behaviour and biological factors
  • maternal circumstances
  • psychosocial factors
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35
Q

WHO framework for tacking social determinants on health outcomes?

A

MICRO - individual

MESA - community

MACRO - public policy

ENVIRONMENT

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36
Q

How do coordination difficulties in early life affect later life outcomes? How can these causes be tackled?

A

Coordination difficulties can be caused by periventricular leukomalacia - health issues

People with coordination issues can also have trouble with tasks such as handwriting - eduction effects

People with coordination difficulties have higher chance of developing mental health problems - health effects

Children with coordination difficulties can develop behavioural issues - eduction

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37
Q

What did Hill et al, (2010) show about exercise and kids?

A

Exercise in the middle of the day improves the children’s abilities to stay on task throughout the rest of the day

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38
Q

Assessment systems for DCD?

A

Movement ABC

  • Manual dexterity
  • Ball skills
  • static balance (posture)

This is however subjective and time consuming

The CKAT (ipad tracing)
- objective and time efficient
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39
Q

Interventions for DCD?

A

Robot guided therapy can improve fine-motor control

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40
Q

Piaget’s task, conclusions and criticisms?

A

Showed baby a toy - the toy was covered and the baby did not reach for it - concluded the baby could not remember the existence if the toy.

HOWEVER - reaching may have been hard - had to reach behind the screen, may not have been in a good position to reach.

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41
Q

What were Violation of expectation tasks?

A

had a screen and a short and tall carrot.

In the expected event the screen had no window, in teh unexpected there is a window

In the large carrot experiment you would expect to see the carrot in the window.

If the babies were surprised then they could had a mental representation and probably form memories

Found babies were surprised

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42
Q

Two types of ways to measure remembering in children?

A

mobile-conjugate reinforcement - putting together two different things and remembering they are together

Operant conditioning

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43
Q

Evidence for operant conditioning in children?

A

DeCasper & Fifer:

Set up a condition that if they increase or decrease their sucking in response to mothers voice vs strangers they are rewarded (i guess). So babies increase or decrease to mothers voice

Also works with familiar story

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44
Q

Evidence for mobile-conjugate reinforcement

A

Put babies in cot. See how much they kick.

Then hook babies leg up to mobile - when they kick the leg the mobile moves

babies learn that if they kick their leg the mobile will move

Then did manipulations, e.g. retention interval,

Will remember 2 weeks later

Found that it was very context specific, i.e. mobile type, cot décor, room.

Reminder increased retention interval

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45
Q

Constraints with developmental trajectories when measuring in different age groups?

A

Can’t keep using the same test - very variable between what some babies can/can’t do

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46
Q

main developments when moving from infancy to toddlerhood?

A

Independent movement

Language

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47
Q

Results from magic-shrinking machine experiments?

A

From 2 can remember.

at 2 years old some photo recognition (30%), re-enactment is at 40% and verbal recall is not good.

Photo recognition is really good at 3, and re-enactment lags slightly, verbal is still pretty bad

At 4 photo and enactment is basically at ceiling but verbal recall is still only 35%

When tested a year later they used the vocab they had 12 months before (frozen in time)

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48
Q

Findings of Peterson and colleagues about stressful events?

A

Interviewed about emergency medical treatment they’d had

The key determinant for memory was whether they possessed adequate language facilities at the time

Language has a big role on certain types of memories

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49
Q

What is infantile amnesia?

A

The fact that people often don’t remember anything pre 5 yrs and almost nothing pre 3 years.

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50
Q

Two factors that may explain infantile amnesia?

A

Lack of language

Lack of sense of self

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51
Q

Mirror/red-dot test of sense of self? How is this developed in terms of episodic memories?

A

Put red dot on mirror where nose is, see if child touches mirror or nose

Then hide Larry the lion, ask later to see if child remembers where Larry is

Children better on red dot test are better at finding Larry.

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52
Q

Trend in terms of use of memory strategies in development to remember?

A

Flavell et al (1966)

Children engage in sub vocal rehearsal increasingly as they develop - big spike between 7 and 10 years old

Kobasigawa

Gave kids a test, also gave them pictures they could use as a strategy, again big spike at 7-10

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53
Q

Evidence regarding knowledge and memory in development?

A

Did two tests on adults and children, one digit span and one on chess pieces

Children are chess experts

Children remember much better than adults on chess task, but much worse on digit.

Shows children do use their knowledge as a help to remember more things.

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54
Q

What is metamemory?

A

A type of metacognition, is both the introspective knowledge of one’s own memory capabilities (and strategies that can aid memory) and the processes involved in memory self-monitoring. Self-rating of memory.

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55
Q

Relationship between metamemory and memory performance?

A

Metamemory is positively related to memory performance

Some research suggests that this may be because overconfidence makes children try harder

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56
Q

What did Gathercole (2004) show about working memory development?

A

Very clear developmental improvement of WM across age up to 14/15

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57
Q

Why is WM so important for development?

A

Kids with poor WM find it hard to concentrate and follow instructions or maths problems

Looks like they are not paying attention/trying

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58
Q

Main points from Allen & waterman (2015) and effects on children?

A

For adults, enactment at encoding is better - specifically for verbal recall

However not for children

Waterman found that for children, enactment is worse.

HOWEVER This is because the (enacted) task is difficult for children.

When changed to make task easier then enactment was also better.

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59
Q

One of the strongest predictors of academic success? (language)

A

Vocabulary level

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60
Q

When do education deficits for children begin, what happens during the school career?

A

Even before school, by the age of 3 there is a gap between SES children and their cognitive test scores. This gap widens through the school career

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61
Q

Five different aspects of language?

A

Phonology: sounds of the language

Lexicon: Words of the language

Semantics: Meanings of words

Pragmatics: Rules for using language in a social context

Syntax: Organisation and grammatical rules for language

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62
Q

Five different stages of language development?

A

Prelinguistic: Crying, cooing, gooing (still has some system - french different to english)

Holophrastic: One word means many things, 50 words by 18 months, 300 by 2 years

Telegraphic: Two or three word phrases i.e. where go? 18 to 24 months

Stage II grammar: between 2 and 3, includes for example ‘s’ as plurals, but may do generalisations - mouses

Adult-like speech: about 5-6 years old

However of course language development continues to be refined into later life

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63
Q

Carey 1978 suggest 6 year olds know how many words?

How many for adults?

A

14,000

Adults know around 70,000

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64
Q

Two arguments about language development, who are the proponents for each?

A

Rationalist/Nature

  • Chomsky/pinker - we are born with it all

Nurture/Emprircist

  • Skinner - we only learn language through entirely learnt structures
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65
Q

What is learning theory? Criticism?

A

Theory supporting Nurture/Empiricist argument.

Learned through classical condition.

We can give feedback for incorrect answers, but model the right answer - if it were purely conditioning you couldn’t give feedback for wrong answers at all

So there is a lack of negative feedback and feedback is not always consistent.

Also children make generalisation: ‘balereening’, hasn’t learned that directly

Children of deaf parents still babble in similar ways to children of hearing parents

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66
Q

What is Chomsky’s universal grammar theory?

A

Originally the language acquisition device

Language is not learned, it grows

idea is that you are born with a set of principles and parameters that constrain you to certain languages - these are different in different languages so the environment shapes how you output them.

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67
Q

Evidence for universal grammar regarding pidgin and creoles (bickerton 1981, 84)?

A

Pidgins develop to communicate and are highly simplified, but the children who grow up with it as a first language make it creole and this is syntactically rich

Like you have a biological drive to create syntax

Language bio program hypothesis

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68
Q

Evidence for universal grammar due to genetic language disorders?

Criticisms?

A

Specific language impairment - SLI - Van der lely & Stollawreck:

Highly heritable condition

Genetic component suggests that we have a natural ability for language

However some evidence it may also be to do with temporal and other aspects of cognition

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69
Q

Evidence for chomsky’s view of a critical period in the child Genie lennenberg.

A

Genie could learn vocab but never learned grammar - there may be a critical period.

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70
Q

The interactionist view of language development?

A

Likely biologically prepared in some way for language development, however the child is an active learner and language develops in the context of behavioural, social and cognitive development

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71
Q

What is child directed speech? What are the reasons for this? What does this say for Chomsky’s view of langauge development

A

Makes the language easier to learn - simplified and recognisable, more pauses and there is more emphasis on the beginning and end of the word. This seems to also apply to sign language.

Evidence that it works, however it is not always necessary to learn a language, cross-cultural differences (when it is there it is helpful, however) (pine 1994)

Suggests that input is better than Chomsky argued.

72
Q

What did Tincoff and Jusczyz (1999) show about 6 month old babies understanding of semantic words?

A

Can look longer a video of mummy if they hear that word and the same for daddy

73
Q

What is the vocabulary spurt in children, is this the same for all?

A

The period where children really take on new words -

sudden big rise

74
Q

What factors may help children learn new words

A

Nature:
- Innate constraints and biases (mutual exclusivity bias) - the new word may apply to the thing that they do not have a label for

Nurture:
- Shared attention and feedback from parents - pointing e.t.c.

Cognitive capacity:
- Gathercole 1995 showed that WM is linked to learning new words

75
Q

Evidence for Mutual exclusivity bias?

A

Mervis and Bertrand (1994)

Child showed familiar object and unfamiliar object and a non-word, asked to pick up the non-word - they will pick up the unfamiliar object

76
Q

What is the emergentist coalition model?

A

Hollich et al 2000

Constraints are not enough by themselves

There is a combination of inbuilt biases but also word learning experience

Particular attention to social context

77
Q

Evidence regarding early vocabulary differences in different SES backgrounds?

A

Hart & Risley (1995)

  • Professional families 215,000 words in one week
  • Low SES only 62,000

Rowe et al 2012 - quality is important too

78
Q

Rowe et al (2013) study on language development?

A

Longitudinal study predictors of vocab at 54 months were SES, parent input, child gesture

Also found the speed of vocab acquisition at 30 months predicted later vocab - especially marked in low SES families

79
Q

What is the Matthew effect? How does this apply to language?

A

The rich get rich and the poor get poorer

Same in language those with disadvantages at the start continue to get more disadvantages and vice versa

80
Q

Interventions to improve language development?

A

Interventions to encourage reading to babies - early

Interventions to improve school readiness

81
Q

Mary Ainsworth definition for attachment?

A

An evolutionary driven, biologically based relationship (with primary caregiver), the principle function of which is to modulate stress in the infant in order to promote physiological, emotional, social and protective advantages.

82
Q

What two systems is the attachment system present to modulate (and protect stress-system)?

A

Fear system and learning (exploratory system)

83
Q

How is attachment organised into a behavioural system?

A
  1. Infant monitors for a threat at a preconscious unconscious or conscious level.
  2. Arousal/Fear is modulated by the the proximity of CG: infant will learn what behaviours are effective at getting a CG response (leads to the emergence of indv diff in emotion expression and regulation)
  3. This is driven by behavioural homeostasis (a state) not an object driven process
  4. System is deacitivated by different responses
84
Q

How do the CG and attachment systems interact?

A

The CG system is inactive when the attachment system is active and vice versa

The attachment system aim is to activate the Cg system?

85
Q

Classifications of the Strange situation test?

A

Secure - Child cries when the mother leaves, is not comforted by stranger and is calmed when mother returns

Insecure (resistant) - Doesn’t mind parent leaving, is comforted by stranger, shows signs of distress, but doesn’t move towards the CG to modulate that stress.

Insecure (avoidant):
Didn’t look for comfort from stranger or mum, avoids the experience of distress altogether.

Disorganised: Strange, unclassifiable behaviour, odd movements, freezing, exaggerated expressions.

86
Q

What are internal working models?

A

Unconscious mental representations/schema.

Activated under threat
Open to revision, but with a bias to stability.

Different IWM for different caregivers: will coalesce into a ‘state of mind’ with respect to attachment.

IWM will organise and filter future relationship theories

87
Q

Different methods for measuring attachment in different age groups?

A

Infants:
- SST

Children:

  • Attachment Q sorts
  • Projective tests
  • Story stem assessment profile
  • Child attachment interview

Adolescents:

  • Inventory of parent and peer attachment (IPPA)
  • Adapted AAI

Adults:
- AAI

88
Q

How do child attachment classification translate into adult terms?

A

Secure/autonomous stays the same

Anxious resistant become preoccupied

Anxious avoidant become dismissing

Disorganised becomes unresolved of fearful

89
Q

Brief summary of the HPA axis?

A

Stress (as detected by amygdala)

Hypothalamus - Anterior pituitary AND sympathetic NS:

  1. Anterior pituitary secretes ACTH which activated the adrenal cortex - which secretes glucocorticoids (cortisol)
  2. Sympathetic NS activates Adrenal medulla which releases catecholamines.
90
Q

Effects of prolonged stress?

A

Prolonged exposure to glucocorticoids early in life can result in increased HPA reactivity

Evidence links HPA reactivity to the link between adversity with poor mental and physical outcomes (Koss et al., 2013)

Candidate hormones include cortisol and oxytocin

Some relationship between stress regulation and attachment

91
Q

Evidence linking stress, cortisol and attachment?

A

Laurent et al. (2016)

Longitudinal study of stress sessions age 1-3

Infants of less sensitive mothers showed elevated cortisol during and following stress exposure

Infants of more sensitive mothers showed better stress regulation (lower cortisol with quicker post-stress recovery)

Some evidence that HPA hyperactivation is related to infant distress

92
Q

Evidence for causal relationships between oxytocin and and HPA reactivity?

A

Pierrehumbert et al (2012)

Perceived stress, HPA reactivity and levels of oxytocin do vary with attachment classification, however the causal nature of this relationship is uncertain.

Does hippocampal damage cause emotion and endocrine dysregulation causing insecurity or does insecurity lead to emotion and hormonal dysregulation and hippocampal damage, in turn causing hippocampal damage.

93
Q

Main areas where attachment classification might affect future outcomes?

A
Play activity
Emotion regulation
Peer relationships
Cognitive development
Social competence
Adult relationships
Mental health
94
Q

How does Secure(B) attachment affect future outcomes?

A

Fonagy et al (1997):
- Predicts preschoolers and school-aged childrens ToM separate of chronological age, verbal mental age and social maturity.

Carlson & Sroufe (1995)
- predicts healthy, stable peer relationships in preschool and early childhood.

Raikes & thompson (2008):
- Associated with exploration and early problem solving capabilities.

95
Q

How does anxious - avoidant (A) attachment affect future outcomes?

A

CG have ignored or rejected attachment signals so they are seen as unavailable and unresponsive.

infants learn to inhibit emotional signals, especially negative signals, may inhibit emotions in time.

McElwain et al. (2003):
Negative emotions (e.g. stress and anger) may become redirected toward inappropriate sources or expressed inappropriately. 

Predisposes children to a later increased risk for later externalising and internalising behavioural problems, may be associated with difficulties in social situations and developing friendships (Carlson & Sroufe., 1995)

96
Q

How does an anxious-resistant classification affect future outcomes?

A

Carlson & Sroufe (1995):

There has been an inconsistent response, infants show exaggerated displays of distress.

Bowlby (1980)
- In preschool and early childhood, easily frustrated, impulsive and overly anxious - see themselves as unable to cope with stress.

Reduced exploration in unfamiliar settings and increased preoccupation with personal suffering, heightened personal fears.

McElwain et al., 2003:
- 3 yr olds less assertive amongst friends

Carlson & Sroufe (1995):
Inappropriately aggressive or excessively passive.

97
Q

Future outcomes seen in disorganised attachment?

A

Seen in three conditions: Abusive parents, Unresolved parents and residential care.

Van Ijzendoorn et al (1999):
66% of children in care were disorganised, showed similar behaviour to those of alcoholic or depressed mothers.

R/F for psychopathology (Van IJzendoorn 2010):

Elevated cortisol response in infancy

Cassidy (1988):
- increased likelihood of controlling behaviour

Lyons-Ruth & Jocobvitz (1999):
- Increased aggression, externalizing disorders and oppositional defiant disorder

98
Q

What is reactive attachment disorder (RAD?

A

Markedly disturbed and developmentally inappropriate social relatedness, normally beginning before 5.

Behaviour as reactive to pathogenic care (Horner, 2008)

Characterised by a failure to develop committed intimate social relationships

Either inhibited or disinhibited.

99
Q

What did O’connor et al., (2000) show about adoption and RAD?

A

165 adopted romanian children were adopted (following severe deprivation) and 52 non-deprived children were adopted and monitored.

111 Assessed at age 6 (they were adopted before 24 months of age)
Parent interview and mesures of cognitive and social development.

There was a dose association between duration of deprivation and severity of attachment disorder behaviours.

These then correlated with attentional, conduct and cognitive ability problems

100
Q

Three explanatory models for how attachment affects later outcomes?

A

Extreme early effects

Lawful discontinuity:

  • Mediating experiences
  • Dynamic interactive
101
Q

What is the extreme early experiences model?

Limitations, and evidence for them?

A

early attachment will predict later development regardless of any changes to the environment.

Inconsistent findings:

  1. Lewis et al., (1984): attachment predicted psychopathology but for boys only
  2. Suess, Grossman & Sroufe (1992):
    attachment predicted 5 yr old outcomes only for girls and only for avoidant attachment.

Carlson & Sroufe (1995) showed the importance of the environment:

  • many studies have focused on low-income, high-risk families
  • not all infants who are securely attached develop problems later but when they do these are associated with environmental continuity
  • So should focus on the impact of continuity and discontinuity.
102
Q

What is lawful discontinuity?

A

Search for situation in which it proves possible to predict when earlier measurements of children’s functioning will (and will not) predict later outcomes.

There are two models concerning this:

  • Mediating experiences model
  • Dynamic interactive model
103
Q

What is the mediating experiences model of attachment?

A

Proposes that (dis)continuity between early attachment experiences and later outcomes are associated with the stability or instability of environmental conditions

Mediator explains relationship between IV and DV

104
Q

Evidence for the mediating experiences model of attachment?

A

Some studies show that when a child’s environment is is changed then attachment can too:

Pace & Zavattini (2011) adoption study.

Assessed attachment patterns in 20 late-adopted (4-7yr olds) in 12 related dyads (non adopted genetically related)

Significant enhancement of late-adopted children’s attachment security, showing change from insecurity to security.

Revision is possible but it is gradual

105
Q

What is the dynamic interactive model of attachment? Evidence?

A

IWMs affect how children perceive and interpret relationships and events:

Booth et al. (1998) found preschool attachment security more stringly predicted aged-8 perceptions of maternal support than the mothers actual behaviour.

Early attachment provides the lens in which future experiences are filtered, including change experiences

e.g. Mother becomes depressed…

Secure attachment: I am loved, people care, turn to others

Avoidant: it is not easy to understand people, mistrust of others, become more withdrawn

Resistant: I am never certain if you are there for me: increased display of insecurity, aggression and depression.

106
Q

Brief embryology of the NS?

A

Fertilized egg - Multicellular blastocyst

Develop 3 germ layers:
Ectoderm (NS comes from)
Mesoderm
Endoderm

Neurulation accurs around 20th day

Form neural tube by 3-4 weeks

107
Q

What is the neural tube?

A

Pluripotent neural precursor stem cells

Rostral (head) of tube develops the fore, mid and hindbrain

precursor cells mitigate outwards - eventually differentiate into neurones

108
Q

What is neuronal differentiation?

How do cells differ?

A

Involves turning genes on/off, differentiation:

  • Action potential differences
  • Neurotransmitter used
  • Receptor molecules incorporated post-synaptically
  • Morphology of axons and dendrites

Also may differentiate to glial cells

109
Q

What is the time course of myelination for the (i) sensorimotor cortex, (ii) association cortices (iii) prefrontal cortex.

A

Sensorimotor cortex is very fast - peak at birth

Association cortex is next - peak at 8 months

Prefrontal is last - peak at 3/4 years

110
Q

Time course of synaptogenesis in development?

A

Two issues:

  • rate of synapse generation
  • number of synapses

Primate studies suggest overall number of synapses increases into adolescence (there is also pruning)

Important areas finish early, other areas are plastic for longer.

111
Q

What is brain plasticity?

A

The ability of the developing brain to respond to and be modified by experience (purves et al., 2007)

112
Q

What is the effect of rich/non-rich environments on development? Evidence?

A

Rich environments are correlated with higher synapse density and better cognitive development.

Greenhouse & Morris Water Maze:
- Showed rats raised in rich environments perform better in the spatial tasks and have increased synaptic density in spatial areas

113
Q

Evidence from amblyopia and critical periods?

A

Amblyopia:

Visual critical periods, amblyopia is misaligned eyes. If it is fixed young enough there are no lasting effects, however if left after the critical period, will never fix.

114
Q

Research in kittens regarding critical periods?

A

If you sew up a kittens eye during critical periods and then later measure neuronal activity, the activity is reduced (to nothing), whereas if you sew an adults up, there is still some

115
Q

Research regarding hippocampal development in spatial awareness task in children?

Research regarding impoverished environments on children?

A

Found only children who were over the age of 7 could do a spatial task. Idea is that this is due to hippocampal development although it is hard to control all other factors.

EEG studies have found that impoverished environments hinder normal brain development

116
Q

Results of fMRI studies on children?

A

Brain will become more focal (focused) and less diffuse with age

Trend for less reliance on sub-cortical systems

117
Q

Results of EEG studies in children?

A

Institutionalised children show higher proportion of low frequency bandwidths

This may show failure of cortical development

118
Q

Results regarding Kanizsa figures (pacman shit) and children?

A

By 7 months they can see the ‘imagined’ contours

When hooked up to EEG you can see different levels of activity when looking at the ‘hidden square’

119
Q

How do areas of memory develop in the brain in different ages?

A

Inferior temporal cortex (end of 1st year)

Dendate Gyrus (hippocampus)

Prefrontal cortex (preschool)

120
Q

What has evidence showed regarding memory and ERPs in children?

A

Infants viewed ordered sequence of events

Viewed photos of that event (old) or a novel event (new), and measured ERPs = no difference in recallers and non-recallers.

However there were differences after a week

Suggests the children that do not remember are having issues with consolidation. This is because immediately after they have the same ERP, but after a week the ERP is gone (in the non-rememberers)

121
Q

Language studies in infants?

A
  1. Better speech discrimination when presented to right ear (LH)
  2. Mehler & colleagues showed greater left-hemisphere activation for normal speech as opposed to backwards speech (vs the right hemisphere)
  3. Homae et al 2006 found right temporoparietal region differentiated between prosodic and flattened speech in 3-month olds.
    - also shows importance of prosody in speech.
    - RH distinguishes.
  4. ERPs of posterior tempo-parietal region in adults between open-class and closed class words:
    - at 20 months they understand the difference - no ERP variation
    - 28 months - 2/3 word sentences - ERP variation
    - 3 years - full sentences - adult-like ERP variation
122
Q

Results regarding numerical cognition in children?

A

When using a habituation paradigm and looking at two dominoe-like images with different number of dots:

  • at 6-months need a ratio of 1:2
  • at 9 months can do 2:3
123
Q

Research regarding numerical cognition in children?

A

Tigger experiment. Get a number of tiggers, put a screen over, add or subtract a tigger, reveal screen = have the expected number or not, look at reaction.

Measure ERP - can see a difference.

Links behavioural with neuroscience studies.

124
Q

Research regarding executive processes in children?

A

Ask to sort objects by certain rules, e.g. colour.

By 2 can sort by one rule

By 3 can sort by 2 rules

At 5 can switch between rules - younger children would persevere with first rule.

fMRI shows progressive maturation of some areas of the PFC correlating with this.

125
Q

What factors affect sleep in development?

A
Maternal smoking 
Maternal stress/anxiety 
Parental education
Breast feeding and nutrition
Temperature
Infant temperament
Developmental milestones
Napping
126
Q

How is sleep studied?

A

Diary studies
Actigraphy - not there yet, but will in the future measure.
Sleep EEG (polysomnography)

Actigraphy and HR
Mobile apps and sensing

127
Q

Types of sleep (measured in polysomnography)?

A

Slow wave - brain sleeping, body might move

REM - dreaming, bodies paralyzed, but brain working

128
Q

What is your sleep cycle in terms of sleep stages

A

50% in stage 2 sleep

20% in REM

30% in other stages

129
Q

Differences in animal sleep needs?

A

Animals need different amounts of sleep

  • Possum = 20 hours
  • Cat = 16 hours
  • Horses = 2 hours
130
Q

How much sleep do we need at different ages?

A

Infants - 16 hours
Teenagers - 9 hours
Adults - 7-8 hours
Elderly <7

131
Q

Why do we sleep?

A

Physical restoration:

  • GH increases overnight
  • No direct relationship between physical activity and amount of sleep, some for quality of sleep

Mental restoration:

  • Learning/memory consolidation - might prune things we don’t need, consolidate what we do
  • improvements in memory following a nap/overnight sleep
  • Problem solving after sleep
  • Brain seems to practice newly learned info (Slow wave)
132
Q

Horne and Minard (1985) results regarding sleep?

A

Ptps unexpectedly given a very busy day:

Measured sleep: similar amount but extra time was spent in slow wave sleep.

133
Q

Lee & Rosen study regarding the sleep cycle in infants?

A

About 8hrs of Quite Sleep, REM and wake across the day

By 4-8 weeks they have more of a day/night cycle

Around 12 weeks develop evidence of sleep spindles (Which seem to have an impact of memory/IQ)

Much of infant sleep is REM 8hrs in infants, 1 hr in adolescence

134
Q

Changes in sleep and puberty?

A

Increases in grey matter in temporal lobe - peaks in puberty then decreases

White matter increases - Jenni & Carskadon (2004)

These changes correspond to changes in sleep patterns
- Decreases in delta sleep, more daytime sleepiness, greater differences between school/weekdays

135
Q

Role of sleep in learning in memory in kids?

A

Gillen-O’Neel et al., (2012)
- Children who sacrifice sleep to cram in extra study time more likely to struggle the next day.

Earlier bedtimes good for you:
- increasing children’s bedtime by an hour has positive effects on many aspects of cognitive performance the next day
Sadeh et al.,2003

Procedural, implicit memory associated with REM

Declarative (explicit) associated with Slow wave sleep (SWS)

136
Q

Difference in REM and SWS in children and adults?

A

Anders et al (1995):

- Greater amount of SWS in children than adults

137
Q

Does sleep play a similar role in memory consolidation in children and adults?

A

Wilhelm et al., (2008)

Procedural memory is generally (inconsistent) not found to increase in sleep in children (it does in adults)

138
Q

Dumay & Gaskell (2007) results regarding vocab learned and sleep?

A

Teach people new words 2 groups (AM group and PM group)

Give immediate memory test

Give a test 12 hrs later (either later the same day or early the next morning)

Then 24 hrs later (when everyone has slept)

Results:

Immediate recall is the same

At 12 hrs later the PM group (who have slept) recall more words

At 24 hrs the AM group remembered more, however the PM group still had the advantage

139
Q

What happens when you teach people non-words that relate to already known words?

A

This will slow down the recognition the the already known word

e.g. Cathedral will be slow if learned cathedruke

140
Q

How might sleep help link different memory systems?

A

Might link fragile memory to robust memory in the hippocampus and neocortex

141
Q

Negative effects of sleep deprivation?

A
Dizziness
Impaired concentration
Irritability
Mood swings and hallucinations
Immune system impairments
142
Q

How are mood, memory and physical performance affected by sleep deprivation?

A

All three negatively affected, mood affected the most.

143
Q

What are the findings regarding sleep deprivation in children?

A

Few studies

Touchette et al, 2007:
- shortened sleep deprivation, especially before the age of 41 months associated with greater behavioural problems and cognitive impairment.

144
Q

Sleep evidence from the time for bed study (Kelly, Kelly & Sacker 2012)?

A

7 year olds N = 11178

At age 7 lack of regular bedtime was related to cognitive abilities (reading/spatial reasoning)
- evidence that this pattern become set in early development and gets worse

Consistent bedtimes are important, as well as:

  • Maternal mental health
  • Daily routines
  • Reading together
  • tv in bedroom
145
Q

Sleep hygiene tips?

A

Regular sleep-wake pattern
Avoid oversleeping
Avoid naps
Avoid stimulants
Don’t exercise close to bedtime, DO exercise in the day
Turn off electronic devices an hour before bed

146
Q

Cain, Gradisar & Mosely, 2010 intervention results?

A

Increased knowledge about sleep - no differences in outcome measures

issue with adherence.

147
Q

Cortisol actions on the immune system?

A

Anti-inflammatory (body’s most potent)

148
Q

Examples of inflammatory over-response?

A

Over months and years if there is a failure to eliminate the ‘insult’
Autoimmunity
Prolonged exposure to toxic agents

149
Q

How can chronic stress affect the immune system?

A

1) increased inflammation
2) Reduced immunity

Can happen through 2 processes:

1.

  • Chronic stress leads to dysregulated HPA activity, (excessive cortisol),
  • cell damage to glucocorticoid receptors
  • Glucocorticoid resistance
  • Unrestricted pro-inflammatory cytokines

2.

  • Cortisol suppression of lymphocytes
  • Increased risk of infection and disease
150
Q

Evidence for chronic stress on reduced immunity and illness?

A

Cohen et al., 2012
- 12 ptps exposed to cold virus, high stress scores meant they were more likely to develop colds

Glaser & Kiecolt-Glaser, 2013
- Stress predicts higher rate of illness following pathogen exposure, protracted wound healing and poorer response to immunisation

Brydon et al 2014:
- lower SES group show greater inflammatory response to increases in stress

151
Q

Evidence regarding childhood exposure to stress and immunity?

A

Childhood exposure to stress causes inflammation & reduced immunity:

Miller & Chen (2010):
135 adolescent girls in chronic family stress assessed 4 times over 1.5 years. Showed increased pro-inflammatory cytokine production, progressive GR desensitisation.

Casserta et al. (2008):
- Health sample of 5-10yr olds assessed 7 times. Parental psych symptoms predicted increased levels of febrile illness and enhanced NK cell functioning.

Can predict later health problems:

  • predicts autoimmune diseases Almeida et al., (2010)
  • Chen et al (2011) adults reared in low-SES environments with high maternal warmth showed fewer pro-inflammatory cytokines than those reared in low maternal warmth
152
Q

Evidence regarding pro-inflammatory cytokines and psychopathology?

A

Benros et al., 2011
- 30-year population based study: autoimmune diseases or hospitalisation for serious infection increased risk of schizophrenia by 29% and 60% respectively

Dowlati et al., 2010
- Meta analysis: significantly more pro-inflammatory cytokines in depressed subjects compared to controls

Vogelzangs et al., 2016:
- elevated pro-inflammatory cytokines positively associated with severity of depression and anxiety

153
Q

Evidence regarding immune dysfuntion and neurodevelopmental disorders?

A

Ashwood et al., 2011
- Good evidence linking the two, especially autism.

Maternal Immune activation (MIA) hypothesis (brown et al., 2004):
- significantly higher second trimester cytokine levels on mothers of offspring with schizophrenia spectrum disorders, than those of controls

Paediatric Autoimmune Neuropsychiatric disorders associated with strep infections
- Swedo et al., 2001: sudden onset of symptoms of OCD and tourettes following strep infection.

154
Q

How is emotion regulation linked to mental health in anxiety and depression in children?

A

Emotion regulation correlated with multiple psychological disorders (Aldao et al., 2010)

Children with anxiety:

  • Higher levels of dysregulated anger, sadness and anxiety compared to non-clinical controls (suveg & Zeman, 2004)
  • Deficits in cognitovely re-appraising situations
  • Actual and perceived difficulties managing anxious feelings (Carthy et al., 2010)

Children with depression:
- more likely to ruminate and less likely to problem-solve or re-appraise (Stegge & terwogt, 2007)

155
Q

How does stress affect emotion regulation, evidence?

A

Stress compromises ER.
- impacts prefrontal cortex. impairs cognitive flexibility, goal-directed behaviour, working memory and self-control.

Raio et al (2013):

  • ptps underwent fear-conditioning and then regulation training.
  • next day acute stress induction OR control task before repeating the fear-conditioning task using new regulation skills.
  • Controls demonstrated fear reduction: stress condition ptps did not.
  • Acute stress impairs the ability to cognitively regulate fear responses
  • glucocorticoid response and elevated noradrenaline = rapid alterations in executive functioning and impairment of the PFC.
156
Q

What is mindfulness?

A

Jon Kabat-Zinn:
Paying attention to the present, non-judgementally, on purpose.

It is both a trait and a state of consciousness.

157
Q

Who first argues for the genetic cause for autism? WHat did they do?

A

Rutter and Folstein (1997):

  • Twin studies
  • Begun the development of some major theories in autism
158
Q

Three main deficits in autism?

A

Imagination/flexibility of thought or activities/interests

  • Unusual or repetitive gestures/actions
  • Pre-occupation with narrow interests
  • Fascination with object parts

Social and emotional communication

  • Language (can be repetitive)
  • Cannot sustain/initiate conversation

Social and emotional interaction

  • Appears unresponsive
  • Absent/unusual eye contact
  • Doesn’t spontaneously share interest or enjoyment
  • Making friends with

Also may be skilled in particular domains (savantism)

159
Q

What WAS the difference between asperger’s and autism in the DSM IV?

A

No deficit in language in aspergers.

160
Q

How has the diagnostic criteria changed in the DSM V?

A

More of a spectrum now

No aspergers.

161
Q

Four different models of autism

A

Theory of mind

Weak central coherence

Executive (dys)function

The empathizing - systematizing theory

162
Q

What is the theory of mind?

What does it explain, what are the criticisms?

A

Deficit in metacognition:

  • Cannot see another’s perspective
  • Mind blindness

Sally/Ann task

Explains:

  • Social communication deficits
  • Joint attention problems (language problems)
  • Pretend play (lack of)

Criticisms:

  • Doesn’t explain repetitive interests/motor behaviour
  • Stereotypical
163
Q

What is weak central coherence theory?

What does it explain, what are the criticisms?

A

Tendency to focus on detail and not the global picture

  • not seeing the forest for the trees.

Pram task

Explains:
- repetitive interests
- some language problems - homophones
The Tear in the dress - might read it as tear as in crying

Criticisms:
- Less apparent in high functioning populations - they tend to do quite well in these tasks

164
Q

What is the executive (dys)function model?

What does it explain, what are the criticisms?

A

Struggle with executive functions:
- Planning, WM, impulse control and inhibition

Frontal lobes

Struggle on WM tasks like N-Back, and tower of hanoi

Explains:

  • Rigidity
  • Repetitive
  • Theory of mind (deficit in planning rather than anything else)

Criticisms:

  • Found in conditions other than autism
  • High IQ is associated with no dysfunction here.
165
Q

What is the empathising-systemising model?

What does it explain, what are the criticisms?

A

Empathising:
- Ability to understand others perspective

Systemising:
- Propensity for an interest in the rules and regulations of a system. Like rule based things, e.g. maths, chess.

High on systemising, low on empathising

Criticisms:

  • Over general: doesn’t really provide evidence
  • Limited evidence base
166
Q

Limitations in understanding biological basis for autism?

A

Limitations in measures

Limitations in knowing where to look

Limitations in knowing how biology links to behaviour

167
Q

Research regarding gaze and autism?

A

Gaze is one of the main predictors of autism severity, can be used from a very early age.

Dalton et al (2005): gaze fixation and face processing.
Autism:
- less fixation overall
- eyes and mouth a lot less than the face
- They look at the eyes and mouth the same amount

Controls activated:
Prefrontal regions, Occipital and fusiform gyrus (identfication)

Autistics activated more:
Amygdala, Left Orbitofrontal gyrus (emotion)

When people with autism might actually be hyper stimulated in the amygdala - this may be why they find it uncomfortable.

It may be that the over-activation in the amygdala means that the identification areas are under activated

May also explain some language and social deficits - because they are avoiding stimulation in this way - critical periods?

168
Q

What did Lombardo et al (2011) find regarding autism?

A

Given two tasks, social and physics task

Right temporal parietal junction was activated differently in controls in the social task.

In autism there was no difference in the tasks.

169
Q

Findings regarding frontal-striatal circuitry, and autism?

A

Delmonte et al 2013:

Can’t just look at one area of the brain, looked at functional connectivity in areas of the brain (what areas tend to light up at the same time):

Anterior cingulate cortex has less cross-talk with Caudate nucleus in social rewards

Medial frontal gyrus has more connectivity with caudate.
Caudate is associated with implicit procedural memory (reaction motor movements)(can’t switch off repetitive behaviours)

Reduced connectivity between nucleus accumbens and paracingulate gyrus, and OFC
- both of these have social roles

There may not be anatomical differences BUT there may be communication deficits in different regions of the brain.

Need longitudinal studies

170
Q

Heritability of Autism? What do we know about it genetically?

A

VERY heritable:

Twin studies have 90% correlation

More males 4:1 - although females may be underdiagnosed

80-85% unknown or multifactorial genetic changes in autism - we don’t know a lot yet.

Multifactorial genetic condition

171
Q

Hormones and autism evidence?

A

Auyeung et al (2010):

High foetal testosterone is linked to:

  • reduced eye contact in children
  • Smaller vocab in toddlers
  • Narrower interests at 4 years
  • Less empathy
  • Increased systemising
  • Number of autistic traits in older children.
172
Q

What is the Q-Chat score? Findings regarding it?

A

Parent reported questionnaire that evaluates autistic traits.

Link between testosterone and Q-CHAT.

173
Q

What biological and behavioural measures do we have for autism?

What’s the benefits and pitfalls of biological?

A

Behavioural:
Q-Chat, Sally-ann, WM, Embedded figures, ADOS, systemising and empathising quotients.

Biological:

  • Objective means of prediction
  • Biomarkers

Benefits of biological:

  • Objective
  • May reveal causation
  • Earlier detection possibly
  • Improvement of behavioural diagnosis
  • Improved validity of early intervention

Pitfalls:

  • Can have poor sensitivity and specificity
  • Expensive
  • Ethics: Specific label from a broad spectrum; disability or difference; reproductive choices.
174
Q

Known biomarkers in autism?

A

Gene profile
Brain size
Eye-movement

Presymptomatic:

  • Family history
  • Foetal testosterone
  • P400 (increased in kids with a FH or sibling)
  • Some studies are 80-90% based on eye movements.
175
Q

Interventions for autism?

A

Behavioural - can help with symptoms
Dietary - very little evidence
Bio-medical -
Pharmacological -

LeGoff 2004: Lego therapy (autistic kids like lego):

  • Have kids in group of three
  • Give them different roles - force them to interact

SULP:

  • Learn social rules
  • use of stories with metacognition
  • rewards in stickers and treats

In Owens et al (2008)

  • SULP and LEGO improved maladaptive behaviour
  • LEGO improved social interaction score