Advanced Anatomy Unit 1 Exam Flashcards
Anatomy
study of the structure of body parts and their relationships to one another
Cytology
study of the cells of the body
Histology
study of the tissues of the body
Developmental anatomy
study of the structural changes which occur from conception to old age
Embryology
study of developmental changes during the first eight weeks of development
6 levels of organization
chemical, cell, tissue, organ, organ system, organism
Types of tissue
epithelial tissue, connective tissue, muscle tissue, nervous tissue
Abdominal regions
right hypochondriac, epigastric, left hypochondriac, right lumbar, umbilical, left lumbar, right iliac, hypogastric, left iliac
Serous membranes
covers organs and cavities of the trunk; composed of connective tissue and simple squamous epithelial tissue
Plasma membrane
forms outer cell boundary and separates the internal environment from the external
Cytoplasm
contains cytosol, cytoskeleton, inclusions, and organelles; site where most cell activity takes place
Nucleus
control center containing DNA
Central dogma
DNA transcripting to RNA, RNA transcribing to proteins
Plasma membrane lipids
phospholipids and cholesterol
Marker molecules
involved in cell to cell recognition (mostly glycoproteins or glycolipids)
Attachment proteins
attach cells to other cells, extracellular molecules, or intracellular molecules
Channel proteins
involved with transportation of substances in and out of a cell
Receptor proteins
contain binding sites that bind to specific substances
Carrier proteins
move substances from one side of the PM to the other
Cytosol
fluid portion of the cytoplasm
Cytoskeleton
provides support and structure and is involved in the movement of cellular structures
Ribosomes
sites of protein synthesis, there are both fixed and free ribosomes
RER
has ribosomes on the outer surface and produces proteins
SER
functional in lipid synthesis, storage of Ca ions in muscle cells, and detoxification
Golgi apparatus
pimp and ride; modifies and packages proteins produced by the RER and lipids produced by the SER
Lysosomes
contain acidic enzymes; abundant in phagocytes; rupture results in self digestion of the cell (autolysis)
Mitochondria
produces ATP
Motile celia
extensions of the plasma membrane that move materials over the cell (fallopian tubes, trachea, bronchi)
Primary celia
involved in sensation (rods, olfactory neurons)
Microvilli
finger-like projections from the PM; increase surface area; found in cells that undergo absorption
Epithelial tissue functions
covers body surfaces, lines hollow cavities, organs, and ducts, and forms glands
Connective tissue functions
protects and supports the body and its organs, binds organs together, stores energy reserves as fat, and provides immunity
Muscle tissue functions
movement and generation of force
Nervous tissue functions
initiates and transmits action potentials, coordinating bodily functions
Primary germ layers within the embryo
endoderm, mesoderm, ectoderm
Tissue derivations
Epithelium from all three germ layers, connective and muscle tissue from the mesoderm, nerve tissue from ectoderm
Tight junctions
watertight seal between cells, PMs fused with a strip of proteins, common between cells that line the GI and bladder
Adherens junctions and components
holds epithelial tissue together; has plaques (dense layer of proteins in the cell membrane), microfilaments, and integral membrane that extends to the other cell membrane
Gap junctions functions and components
small space between the PMs of two cells; cell communication between cells with ions and small molecules (heart and smooth muscle of gut); connexons (protein channels that form fluid filled tunnels)
Desmosomes functions and components
resists cell separation and disruption; Similar structure to adherens junction except intracellular intermediate filaments cross cytoplasm of cell; support of cardiac muscle
Hemidesmosomes
half of desmosomes; connects cells to extracellular material (basement membrane)
Epithelial tissue features
closely packed cells with little extracellular material, sits on basement membrane, avascular, good nerve supply, rapid cell division
Epithelial tissue functions
protection, filtration, lubrication, secretion, digestion, absorption, transportation, excretion, sensory reception, reproduction
Basement membrane components
basal lamina (epithelial cells and collagen), reticular lamina (secreted by connective tissue, reticular fibers)
Basement membrane functions
guide for cell migration during development, thickens due to collagen and laminin production
Covering and lining epithelium
epidermis of skin, lining of blood vessels and ducts, lining of respiratory, GI, reproductive, and urinary tracts
Glandular epithelium
secreting portion of glands, thyroid, adrenal, and sweat glands
Glands (glandular epithelium)
a single or mass of epithelial cells adapted for secretion, derived from epithelial cells that sank below the the surface during development
Endocrine glands
ductless; secrete hormones into bloodstream, and these hormones help maintain homeostasis
Exocrine glands
secrete products into ducts that empty at the surface of covering and lining epithelium or directly onto a free surface; connected to the surface by ducts
Unicellular gland classification
goblet cells
Multicellular gland classification
branched or unbranched, tubular or acinar, sweat glands
Merocrine glands
form the secretory products and discharge them by exocytosis (sweat and salivary glands)
Apocrine glands/decapitating
accumulate secretary products at the apical surface of the secreting cell; that portion then pinches off from the rest of the cell to form the secretion with the remaining part of the cell repairing itself and repeating the process (mammary and cercumum glands)
Holocrine glands
accumulate the secretory product in the cytosol; cell dies and its products are discharged, then is replaced by new cells (sebaceous and meibomian glands)
What is connective tissue derived from?
mesoderm and mesenchyme
Fibroblasts
immature cells that secrete fibers and matrix
Adipocytes
immature cells that store energy in the form of fat
Macrophages
develop from monocytes and engulf bacteria and debris by phagocytosis
B lymphocytes
plasma cells develop from this; produce antibodies
Mast cells
produce histamine that dilate small BV
Mesenchyme
found almost exclusively in the embryo, is the tissue form from which all other connective tissue eventually arises; Irregularly shaped cells,
semifluid ground substance with reticular fibers
Mucus connective tissue (Wharton’s jelly)
found in the umbilical cord of the fetus; Star-shaped cells in jelly-like ground substance
Loose connective tissues
areolar connective tissue, adipose tissue, reticular tissue
Areolar connective tissue
contains fibroblasts, plasma cells, macrophages, mast cells and a few white blood cells; Gelatinous ground substance; found in the subcutaneous layer of the integument
Adipose connective tissue
consists of adipocytes which are specialized for storage of triglycerides; reduces heat loss through the skin, serves as an energy reserve, supports, protects, and generates considerable heat to help maintain proper body temperature in newborns
Reticular connective tissue
consists of fine interlacing reticular fibers and reticular cells; forms the stroma of certain organs; helps bind the cells of smooth muscle
Types of dense connective tissue
dense regular connective tissue, dense irregular connective tissue, elastic connective tissue
Dense regular connective tissue
Collagen fibers in parallel bundles with fibroblasts between bundles of collagen fibers; forms tendons
Dense irregular connective tissue
contains collagen fibers that are irregularly arranged and is found in parts of the body where tensions are exerted in various directions; found in heart valves, the perichondrium, the tissue surrounding cartilage, and the periosteum (whites of eyes)
Elastic connective tissue
Branching elastic fibers and fibroblasts
Can stretch & still return to original shape
Lung tissue, vocal cords, ligament between vertebrae
4 main types of cells of the epidermis
90% of cells keratinocytes and 5-6% melanocytes, Langerhan cells, and Merkel cells
Langerhan cells
antigen presenting cells; dendritic cells and are part of the immune system
Merkel cells
touch sensors located in the stratum basale
Keratinocytes
produce keratin; cells either divide into more stem cells or transit cells that will eventually become the cornified most superficial layer of the epidermis
Melanocytes
produce melanin and are found in the stratum basale
Stratum basale
deepest layer, one layer thick, mitosis occurs here
Stratum spinosum
several layers thick, lots of desmosomes present
Stratum granulosum
contains keratohyalin granules and lamellated bodies; 2-5 cell layers thick
keratohyaline granules
gives epidermis its strength
lamellated bodies
lipid filled bodies that give the epidermis its waterproofing properties
stratum lucidum
“clear layer” that is only found in thick skin
Stratum corenum
20-30 cells thick in thin skin (thicker in thick skin), provides protection from external environment, dead cells
order of the epidermis layers from deep to superficial
Basal, spinosum, granulosum, lucidum, corneum
Dermis regions
papillary layer and reticular layer
Papillary layer
superficial layer of the dermis; composed of loose connective tissue; has projections called dermal papillae which indent the epidermis
Reticular layer
deep to the papillary layer, composed of dense irregular connective tissue
Sebaceous glands
found all over body except for palms of hands and soles of feet; secrete oily secretion called sebum; lubricates hair and skin & inhibits growth of certain bacteria
Eccrine sweat glands
more numerous, lots on palms, soles of feet, and forehead
Apocrine sweat glands
found in the axillary and anogenital areas; begin to function at puberty
Ceruminous glands
modified apocrine glands found lining the external ear canal (ear wax)
Mammary glands
specialized sweat glands which secrete milk