Adult II Final Review Questions Flashcards
Pancytopenia
When WBC, PLT, RBC are all low
Desquamation
Skin damage/irritation r/t external radiation tx.
WET - Blistered sunburn
DRY - Red, sunburn
Induction Chemo
- Acute forms start immediately
- Very ill patient - bone marrow depression
- Multiple drugs used
- Decrease drug resistance
- Minimize toxicity
- Interrupts cell growth at diff. points in cycle.
- Toxicity depends on chemo combo
Consolidation Chemo
- Started AFTER remission is achieved
- Additional course of chemo given
- Goal: eliminate any remaining cx cells
Maintenance Chemo
2-3 low weekly dose therapy
Goal: stay in remission
ANC Formula
ANC = WBC x (Segs + Bands)
When would you expect to see SVCS?
OBSTRUCTION of venous drainage in upper thorax by tumor
When would you expect to see Tumor Lysis Syndrome
Seen within 24-48hr of chemo
-Cells die rapidly & intracellular particles (PO4,uric acid, K+) dump into blood system
When would you expect to see SIADH
From lung cancer cells that release ADH
S/S SVCS
- Facial Edema
- JVD
- HA
- Dyspnea
- Visual disturbances
- Chest Pain
- Dysphagia
BUN
Tests renal function
Varies with meals
Creatinine
[0.5-1.5]
- Muscle breakdown, affected by muscle mass
- Indicator of renal function, used to determine effectiveness of dialysis
Creatinine Clearance
- Estimates GFR
- Ratio of serum/urine
GFR
.
Proteinurea Screening
Standard urine dipstick testing to identify early stages of KD
Best estimate of renal function
Creatinine
Which renal function is used to evaluate the effectiveness of dialysis
Creatinine
Types of peritoneal dialysis
- Intermittent
- Continuous Ambulatory PD
- Continuous Cyclic PD
Intermittent PD
several times a day with complete exchanges
Continuous Ambulatory PD
- Four times a day at home q6hr
- May keep tubing intact or disconnect
- Dialysate remains in abd until next exchange
Continuous Cyclic PD
“Think Machine”
1-2L remains in the abd during day
Renal Diet for Renal Disease
Limit dietary protein watch citrus, tomatoes Limit K+ Restrict phosphate to <100mg/day Avoid-milk, cheese, egg yolks, meat, fish, nuts
Common medications used for ESRD
Kayexalate & Loop diuretic = Hyperkalemia
Phoslo & calciferol (vit D) = Hypocalcemia
CCB, BB, K+ depleting diuretic= HTN
simvastatin (Zocor)
Use: Cholesterol lowering medication
Monitor: LFTs
NO grapefruit products!
Nitroglycerin
Use: Vasodilation dilates coronary arteries to increase blood flow to ischemic areas during unstable angina
Monitor: BP/HR before/after admin
Propranolol (Inderal) / metoprolol (Lopressor)
Beta blocker
Use: Directly decreases myocardial contractility which decreases oxygen demand from muscle, decreases HR
Monitor: bradycardia, HypoTN, wheezing
NOT FOR ASTHMA
Cardizem
Calcium Channel blocker
-Decrease strength of contraction and controls HR
-decrease O2 demand
Monitor: use with dig (dig tox), edema, flushing, HR, dizziness
Enalapril (Vasotec)
.
Valsartan (Diovan)
.
Questran
mixes and binds with cholesterol to excrete more cholesterol
Steps for administering nitro
- Sit or lie down
- 3x5 rul- take 1 q5min x3
- Call EMS if not relieved after 1st dose
Things that affect (decrease) Preload
- Lasix
- High-Fowler w/feet down
- Fluid restriction
Things that affect contractility
DIG
BB
CCB
Things that affect Afterload
ACE
ARB
Nitrates (Nitro)
CCB
Meds that decrease HR
BB
DIG
What is atypical angina
SOB, dizziness, fatigue weakness
-Usually in elderly women & diabetic hard to dx b/c no chest pain
Systolic Failure
Pump doesn’t work/contraction inadequate
Caused by dilation of LV
S3, EF <40%
Diastolic Failure
Disorder of relaxation and filling
Caused by hypertrophy
S4, EF is normal (55-60)
Left Sided HF
Dyspnea on exertion orthopena crackles PND Blood tinged sputum S3, S4
Right Sided HF
Peripheral edema Weight gain JVD hepatomegaly ascites anoreaxia
EARLY signs of pulmonary edema
Apprehension
Restlessness
Best lab to check CHF
BNP
Serevent (Salmeterol)
Long-acting B2-agonist
-safety issues when not taking w/CCsteroid
Atrovent (ipratropium)
short-acting anticholinergic, bronchodilator
Solu-Medrol (methylprednisone)
IV Anti-inflammatory, corticosteroid
Flovent
Inhaled Anti-inflammatory corticosteroid
Singulair
leukoriene antagonist
allergy, cold, cough remedies, bronchodilator
What is the cardiac condition associated with COPD
Cor Pulmonale
s/s same as Rt-sided HF
Combivent
Combo Atrovent + Albuterol short acting rescue inhaler
What lab is used for DM?
Microalbumin
What drug is given to decrease serum K+
Kayexalate & Loop diuretic
What does Phoslo do?
Decrease Phosporus to tx hypocalcemia
Dialysis Diet
Increase biological protein
Limit other protein, K+, phosphorus, Na+
Classic parkinson’s symptoms
T=Tremor
R=rigidity
A=Akinesia/bradykinesia
P=postural instibility
Sign os silent aspiration
Runny nose
gurgling speech
cough
Sinemet
Replaces dopamine GOOD for elders TAKE ONE EMPTY STOMACH -combo give with carbidopa SE: on/off effect orthostatic hypotension Dry mouth Avoid alcohol dark urine/sweat= NORMAL
What class of drug stimulates dopamine receptors?
Dopamine agonist Dont recommend for elder Teach: orthostatic hypotension hallucination/drowsiness
MS is characterized by
exacerbations and remissions
relapsing-remitting =return to baseline
primary-progressive= steady decline
MS symptom management
Avoid aggravating factors:
- Temperature extremes
- Respiratory infection
- Emotion
- Physical exertion
- Postpartum
MS meds - Cholinergic
Urecholine = urinary retention
monitor for hypotension
MS meds- Anticholinergic
Ditropan =tx spastic bladder, freq, urgency
MS meds Immunomodulators
Beta interferon- Avonex
Binds with T cells to prevent them from sending signals to attack myelin
MS meds - immunomodulators
Copaxone = myeline decoy
MS meds - immunomodulator
Cytoxan - Kills T cells to prevent attack
MS meds corticosteroids
to reduce inflammation
CVA Early detection
F = facial droop A = arm drift S = slurred speech T= time, call 911/hospital
Right Sided CVA S/S
Reckless Right, motoR
- Spatial deficits
- Poor judgment
- Unaware of deficits
- LEFT motor/sensory problems
Left sided CVA S/S
- Aphasia
- Cautious
- Intellectual impairment
- Depression, frustration
- RIGHT motor/sensory problems
Stroke prevention
Control manage HTN, Cholesterol
Anticoagulation
Embolic Stroke
RAPID
plaques or tiss trave and become lodged, origin usually endocardial tissue
Wernickes aphasia
Receptive aphasia
Give VISUAL instead of verbal cues
Broca’s aphasia
Expressive aphasia
CVA Management
Anti-HTN (not routine only if BP >185/110)
HTN med resumed after 24hr
*IV Fluids to maintain BP above 150 (perfusion)
*Correct BS
*TX FEVER W/ Acetaminophen
*Tx Constipation
What is the penumbra
Area outside the area of cell death
Four ways to protect the penumbra
Keep BP up
TpA
O2
Control BS, temp, constipation
Dysphagia Diet
Stage I = Severe, pureed
Stage II = baby food meats, scrambled eggs
Stage III =Ground meat w/ gravy, tuna
Stage IV =Swallow most food well, soft diet, soft foods
TB screeing
- Ask if positive
- Not test if positive reactor
- Use MANTOUX not tine
Mantoux/ PPD
Given intradermal Read 48-72hrs Must have induration to be positive MEASURE INDURATION NOT REDNESS <0-4mm = Not significant 5mm= only significant for close contact/immunosuppressed/HIV 10mm=increased risk healthcare worker, prison, foreign born, homeless 15mm=everyone else
QFT gold test
New CDC recommendation
One blood draw
Less false positive no return visit
TB sputum smear
Does not differentiate TB from other mycobacterium
TB Precautions
PAPR
N-95
Negative pressure room
GLOVES, MASK, no gown
HIV, Stage 1
2-4wks after exposure
ANTIBODY TESTS ARE NEGATIVE
RETEST WITHIN 6 MONTHS
Long term non PROGRESSOR
HIV positive > 10yrs
Reasons: Genetics & Lifestyle
Long term SURVIVOR
AID > 8yrs
Reasons: Anti-viral meds & supportive therapies
Screens for HIV 1
ELISA, 2 wks- 6mo after infection
Used to confirm ELISA
Western Blot Assay
Tests for HIV-1 & HIV-2
Rapid tests
Viral load
HIV/RNA cell count
>55,000/mm3 indicates high risk of progression to AIDS in 3yrs
This monitors immune fuction
CD4+ counts
500 Few s/s are present
MAC (Mycobacterium avium complex)
BACTERIAL
- High fever
- Night sweats
- weight loss
PCP (pneumocystis carinii)
PROTOZOAN/ ATYPICAL FUNGUS
“PCJ”
Lung infection
TX with LONG TERM BACTRIM
CMV (cytomeaglovirus)
VIRAL
*LEADING CAUSE OF BLINDNESS IN AIDS
tx antiviral
Kaposi’s Sarcoma
NEOPLASM
Most common Cx seen in HIV
Brown-purple lesions skin & mucous membranes
AIDS dementia complex (ADC)
VIRUS damages brain/nerves
Cognitive changes, motor impairment
Nursing DX: RISK FOR INJURY
Wasting Syndrome
TX ORAL SUPPLEMENTS