Adult II Final Review Questions Flashcards
Pancytopenia
When WBC, PLT, RBC are all low
Desquamation
Skin damage/irritation r/t external radiation tx.
WET - Blistered sunburn
DRY - Red, sunburn
Induction Chemo
- Acute forms start immediately
- Very ill patient - bone marrow depression
- Multiple drugs used
- Decrease drug resistance
- Minimize toxicity
- Interrupts cell growth at diff. points in cycle.
- Toxicity depends on chemo combo
Consolidation Chemo
- Started AFTER remission is achieved
- Additional course of chemo given
- Goal: eliminate any remaining cx cells
Maintenance Chemo
2-3 low weekly dose therapy
Goal: stay in remission
ANC Formula
ANC = WBC x (Segs + Bands)
When would you expect to see SVCS?
OBSTRUCTION of venous drainage in upper thorax by tumor
When would you expect to see Tumor Lysis Syndrome
Seen within 24-48hr of chemo
-Cells die rapidly & intracellular particles (PO4,uric acid, K+) dump into blood system
When would you expect to see SIADH
From lung cancer cells that release ADH
S/S SVCS
- Facial Edema
- JVD
- HA
- Dyspnea
- Visual disturbances
- Chest Pain
- Dysphagia
BUN
Tests renal function
Varies with meals
Creatinine
[0.5-1.5]
- Muscle breakdown, affected by muscle mass
- Indicator of renal function, used to determine effectiveness of dialysis
Creatinine Clearance
- Estimates GFR
- Ratio of serum/urine
GFR
.
Proteinurea Screening
Standard urine dipstick testing to identify early stages of KD
Best estimate of renal function
Creatinine
Which renal function is used to evaluate the effectiveness of dialysis
Creatinine
Types of peritoneal dialysis
- Intermittent
- Continuous Ambulatory PD
- Continuous Cyclic PD
Intermittent PD
several times a day with complete exchanges
Continuous Ambulatory PD
- Four times a day at home q6hr
- May keep tubing intact or disconnect
- Dialysate remains in abd until next exchange
Continuous Cyclic PD
“Think Machine”
1-2L remains in the abd during day
Renal Diet for Renal Disease
Limit dietary protein watch citrus, tomatoes Limit K+ Restrict phosphate to <100mg/day Avoid-milk, cheese, egg yolks, meat, fish, nuts
Common medications used for ESRD
Kayexalate & Loop diuretic = Hyperkalemia
Phoslo & calciferol (vit D) = Hypocalcemia
CCB, BB, K+ depleting diuretic= HTN
simvastatin (Zocor)
Use: Cholesterol lowering medication
Monitor: LFTs
NO grapefruit products!
Nitroglycerin
Use: Vasodilation dilates coronary arteries to increase blood flow to ischemic areas during unstable angina
Monitor: BP/HR before/after admin
Propranolol (Inderal) / metoprolol (Lopressor)
Beta blocker
Use: Directly decreases myocardial contractility which decreases oxygen demand from muscle, decreases HR
Monitor: bradycardia, HypoTN, wheezing
NOT FOR ASTHMA
Cardizem
Calcium Channel blocker
-Decrease strength of contraction and controls HR
-decrease O2 demand
Monitor: use with dig (dig tox), edema, flushing, HR, dizziness
Enalapril (Vasotec)
.
Valsartan (Diovan)
.
Questran
mixes and binds with cholesterol to excrete more cholesterol
Steps for administering nitro
- Sit or lie down
- 3x5 rul- take 1 q5min x3
- Call EMS if not relieved after 1st dose
Things that affect (decrease) Preload
- Lasix
- High-Fowler w/feet down
- Fluid restriction
Things that affect contractility
DIG
BB
CCB
Things that affect Afterload
ACE
ARB
Nitrates (Nitro)
CCB
Meds that decrease HR
BB
DIG
What is atypical angina
SOB, dizziness, fatigue weakness
-Usually in elderly women & diabetic hard to dx b/c no chest pain
Systolic Failure
Pump doesn’t work/contraction inadequate
Caused by dilation of LV
S3, EF <40%
Diastolic Failure
Disorder of relaxation and filling
Caused by hypertrophy
S4, EF is normal (55-60)