ADRs Flashcards
1
Q
Biguanides
A
BBW: Renal failure N,V,D Anorexia Metallic taste Modest weight loss - NO WEIGHT GAIN Macrocytic anemia Increased hypoglycemia potential in comb w/sulfonyureas
2
Q
SGLT2 Inhibitors
A
BBW: Amputation UTI Vaginal Candidiasis Dehydration Possible link to fournier's gangrene (genital gangrene)
3
Q
GLP-1 Agonists
A
BBW (Liraglutide): Thryoid C Cell tumors
N,V,D
Injection site reaction
4
Q
DPP-IV Inhibitors
A
UTI HA URIs Drug-induced pemphigus (blister skin reaction) Angioedema with ACE inhibitors Joint Pain
5
Q
Sulfonylureas
A
*Glyburide: has more ADRs; most hypoglycemia; avoid this in the elderly Hypoglycemia Weight Gain N,V Heartburn
6
Q
Thiazolidinediones
A
Weight Gain Anemia Edema HF URI HA Sinusitis Myalgia Pharyngitis Fractures Potential MI
7
Q
Alpha-Glucosidase Inhibitors
A
Flatulence
Diarrhea
Abd Pain
Elevated serum transaminases
8
Q
Amylin Analog
A
BBW: Hypoglycemia in T1DM
N,V
Hypoglycemia (T1DM)
9
Q
Insulins (General)
A
Hypoglycemia
Weight Gain
Lipohypertrophy
Lipoatrophy
10
Q
Long-Acting Insulins
A
Burns with injection
Detirmir doesn’t burn
11
Q
Rapid-Acting Insulins
A
Pts could get hypoglycemic if the do not eat right away after taking it
12
Q
Intermediate-Acting Insulins
A
Harder to manage
13
Q
Premixed-Insulins
A
Very hard to adjust
