ADRs Flashcards

1
Q

ABx to avoid in pregnancy

A

tetracyclines
aminoglycosides
sulphonamides and trimethoprim

quinolones: the BNF advises to avoid due to arthropathy in some animal studies

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2
Q

CVD drugs to avoid in pregnancy

A

ACE inhibitors
Angiotension II receptor antagonists
Statins
Warfarin

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3
Q

Diabetes drugs to avoid in pregnancy

A

sulfonylureas

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4
Q

Anti epileptics avoid in pregnany

A

sodium valp
Phenytoin
carbamazepine

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5
Q

Drugs that worsen psoriasis

A

BBlockers
lithium
antimalarials
NSAIDs
ACE inhibitors
infliximab

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6
Q

Contraindicated in HF

A

Verapamil
Pioglitazone
flecanide

NSAIDs/Glucocorticoids (use w caution as cause fluid retention)

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7
Q

Worsen seizure control

A

alcohol, cocaine, amphetamines
ciprofloxacin, levofloxacin
aminophylline, theophylline
bupropion
methylphenidate (used in ADHD)
mefenamic acid

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8
Q

Avoid in asthma

A

Bblockers
NSAIDs
Adenosine

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9
Q

Lithium SEs

mild toxicity

intermediate

Late

A

Tremor

lethargy

arythmias,seizures,coma,renal failure, diabetes inspidus

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10
Q

Fludrocortisone SEs

A

Hyptertension/soidum and water retention

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11
Q

Vancomycin
gentamicin
SEs

A

ototoxicity
nephtotoxicity

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12
Q

CCB SEs

A

hypotension, bradycardia, peripheral oedema, flushing

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13
Q

Metronidazole and disulfiram

A

sweating
flushing
N&V

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14
Q

MOA inhibitor SE

A

hypertensive crisis

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15
Q

do not prescribe ACEi w

A

NSAIDS

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16
Q

BBlockers contraindications

A

PVD
And asthma

17
Q

Ciclosporin ADRs

A

Nephrotoxic
HTN

18
Q

Bblockers SE

A

erectile dysfxn

19
Q

Tacrolimus w all heparins

A

increase k

20
Q

tramadol not with? why

A

SSRI
serotonin syndrome

21
Q

cyclizine SE

A

urinary retention/constipation
dry mouth

22
Q

fluoxetine SE

23
Q

all heparins can cause

A

hyperkalaemia

24
Q

Aspirin SE

A

iron defiency anaemia

25
Morphine ADRs
urinary retention renal excreted so can accumulate in renal failure
26
citalopram and dabigatran
precipitate bleed
27
carbamazipine SE
hyponatraemia
28
Omeprazole in increases risk of which infection
C.diff
29
anticholinergic excess
'mad, red, dry, blind'