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Pharmacology (Keef) > adrenergics and antiadrenergics > Flashcards

adrenergics and antiadrenergics Flashcards

1
Q

A drug that is non selective alpha adrenoceptor

A

oxymetazoline

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2
Q

A drug that is selective for alpha 1 adrenoceptor

A

phenylephrine

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3
Q

A drug that is selective for alpha 2 adrenoceptor

A

brimonidine

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4
Q

A drug that is selective for beta 3 adrenoceptor

A

mirabegron

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5
Q

A drug that is selective for beta 2 adrenoceptor

A

salbutamol (catechol)
terbutaline (non catechol)

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6
Q

A drug that is selective for beta 1 adrenoceptor

A

dobutamine

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7
Q

a non selective beta adrenoceptor drug

A

isoprenaline

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8
Q

non selective adrenoceptor drugs

A

adrenaline
norepinephrine
dopamine (a1 + b1)

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9
Q

indirect adrenergic agonists, that is a MAOA inhibitor

A

moclobemide

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10
Q

indirect adrenergic agonist, that is a NE reuptake inhibitor

A

imipramine (tricyclic antipressants)
reboxetine

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11
Q

indirect adrenergic agonist, that displaces endogenous NE

A

pseudoephedrine (decongestants)
ephedrine

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12
Q

direct adrenergic antagonist, specific for alpha 1 receptor

A

prazosin
tamsulosin
+most drugs with -(Z)osin

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13
Q

direct adrenergic antagonist, specific for alpha 2 autoreceptor

A

yohimbine (no longer in clinical use due to abuse as weight loss and impotence supplements)

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14
Q

direct adrenergic antagonist, nonspecific for alpha receptors

A

phenoxybenzamine (irreversible)

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15
Q

direct adrenergic agonist, nonselective beta 1/2

A
  • timolol (low lipophilicity = less local anaesthetic like membrane stabilizing effect = allows for topical application to the eye = treats glaucoma)
  • propranolol (lipophilic)
  • sotalol
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16
Q

direct adrenergic agonist, selective beta 1

A

-bisoprolol (lipophilic)
-betaxolol (low lipophilicity = topical application on the eye to treat glaucoma)

17
Q

indirect adrenergic agonists (used to decrease NE synthesis)

A

methyldopa

18
Q

indirect adrenergic agonist (at presynaptic autoreceptors)

A

dexmedetomidine (sedative)
clonidine (centrally acting, antihypertensive)

Pharmacology (Keef) (4 decks)

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