Adrenergics Flashcards

1
Q

(Direct Acting Adrenergic Agonists)

Non selective alpha

A

Epi
NEpi

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2
Q

(Direct Acting Adrenergic Agonists)

Selective alpha 1

A

(Tip: Remember the -zolines)

Methoxamine
Phenylephrine
Mephentermine
Metaraminol
Midodrine
Oxymetazoline
Tetrahydrozoline
Xylometazoline

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3
Q

(Direct Acting Adrenergic Agonists)

Selective alpha 2

A

Tip: Remember -nidine and Guan-

Clonidine
Apraclonidine
Moxonidine
Brimonidine
Tizanidine
Lofexidine
Guanfacine
Guanabenz
α-methyldopa
dexmedetomidine
Clenbuterol.

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4
Q

(Direct Acting Adrenergic Agonists)

Non Selective Beta

A

Isoproterenol/Isoprenaline
Epi
NEpi

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5
Q

(Direct Acting Adrenergic Agonists)

Selective Beta 1

A

Dobutamine
Denopamine
Xamoterol
Prenalterol

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6
Q

(Direct Acting Adrenergic Agonists)

Selective Beta 2

A

Tip: remember -erol

Albuterol/Salbutamol (since B2 acts on bronchi)

•Short acting
Bitolterol
Fenoterol
Isoetharine
Metaproterenol
Procaterol
Terbutaline
Ritodrine

• Long Acting
Formoterol
Salmeterol

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7
Q

(Direct Acting Adrenergic Agonists)

Selective Beta 3

A

Tip: remember -egron

Mirabegron
Solabegron
Amibegron
Vibegron

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8
Q

(Indirect Acting Adrenergic Agonists)

Neuronal release

A

Amphetamine
Tyramine
Methamphetamine

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9
Q

(Indirect Acting Adrenergic Agonists)

Re-uptake inhibitors

A

Cocaine
Tricyclic Antidepressants
Atomoxetine

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10
Q

(Indirect Acting Adrenergic Agonists)

MAO inhibitors

A

Phenelzine
Tranylcypromine
Selegiline

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11
Q

(Indirect Acting Adrenergic Agonists)

COMPT inhibitors

A

Entacapone
Tolcapone

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12
Q

Alpha 1 Agonist

Prominent Pharmacological Action (PPA)

A

Vasoconstriction

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13
Q

Alpha 1 Agonist

Principal Therapeutic Uses (PTUs)

A

Pressor agents
(Rx of hypotension & shock – methoxamine & phenylephrine),

Nasal decongestants (oxymetazoline, tetrahydrozoline, xylometazoline, naphazoline & some preparations of phenylephrine).

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14
Q

Alpha 1 Agonists

Adverse Effects (AEs)

A

Hypertension, headache, reflex bradycardia, excitability, restlessness, dry mouth, sedation & rebound hypertension ff. abrupt withdrawal.

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