Adrenergic Receptors/effects Of Activation

Question 1

Alpha 1

Answer 1

Innervates most vascular smooth muscle –> contraction
Pupillary dilator muscle –> contraction (dilates pupil)
Pilomotor smooth muscle –> erects hair
Prostate –> contraction
Heart –> increases force of contraction (+ inotropy)

Question 2

Alpha 2

Answer 2

Platelets –> aggregation
Adrenergic/cholinergic nerve terminals –> inhibits transmitter release
some vascular smooth muscle –> contraction
Fat cells –> inhibits lipolysis

Question 3

Beta-1

Answer 3

Heart –> +chronotropy and +inotropy

Juxtaglomerular cells –> increase renin release

Question 4

Beta-2

Answer 4

Respiratory, uterine, and vascular smooth muscle –> promotes smooth muscle relaxation
Skeletal muscle –> promotes K+ uptake
Human liver –> Activates glycogenolysis

Question 5

Beta-3

Answer 5

Bladder –> Relaxes detrusor muscle

Fat cells –> Activates lipolysis

Question 6

Dopamine-1 receptor

Answer 6

Smooth muscle –> dilates renal blood vessels

Question 7

Dopamine-2 receptor

Answer 7

Neve endings –> modulates transmitter release