Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Pharm drugs HC > Adrenergic drugs--Hwa > Flashcards

Adrenergic drugs--Hwa Flashcards

1
Q

Where are alpha 1 receptors located?

A

Everywhere

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Where are alpha 2 receptors located?

A

On the blood vessels

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Where are beta 1 receptors located?

A

On the heart

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Where are beta 2 receptors located?

A

Respiratory tract, blood vessels, and uterus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What do alpha 2 receptors do?

A

Vasoconstriction, some inhibition of NE (negative feedback loop)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Name the alpha 1 agonist drugs

A

Phenylephrine (Neosynephrine) and oxymetazoline

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Name the alpha 2 agonist drugs

A

Clonidine (Catapress) and dexmedetomidine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Name the Beta 1 selective agonists

A

Dobutamine (Dobutrex)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Name the Beta 2 selective agonists

A

Albuterol (Ventolin), salmeterol, terbutaline

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Name the non-selective beta agonists

A

Isoproterenol (isuprel)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Name the non-selective alpha ANTagonists

A

phenolamine and phenoxybenzamine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Name the A1 selective ANTagonists

A

Prazosin, Tamsulosin, Doxazosin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Name the nonselective beta blockers

A 
propranolol 
Timolol
Pindolol
Sotalol
Labetolol
Carvedilol
Nadolol
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Name the beta 1 selective antagonists

A

metoprolol

atenolol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What patient groups are we worried about giving beta 2 nonselective blockers?

A

COPD patients, asthma patients. Also, diabetics because Beta 2 blockers inhibit insulin, glycogenolysis and gluconeogenesis. After an insulin shot, diabetics then become more prone to hypoglycemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is isoproterenol used for?

A

Vasodilation and increase HR (non-selective beta blocker)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What are the side effects of isoproterenol?

A

tachycardia, BP, arrhythmias

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What is phenylephedrine used for?

A

Nasal decongestion, mydriatic, hypertensive

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

What is phenylephedrine used for?

A

Vasoconstriction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

What is clonidine used for?

A

hypotension, menopausal flushing, migraine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

How is clonidine delivered?

A

IV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

What are the effects of clonidine administration?

A

Acute hypertensive response

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

What are the side effects of clonidine?

A

dry mouth, sedation, contact dermatitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

What is dobutamine used for?

A

Cardiogenic shock

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

What are the effects of dobutamine?

A

Increased HR and contractility, dilation of renal and mesenteric vessels

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

What are the side effects of dobutamine?

A

Tachycardia, hypertension, hypotension, ectopic activity

27
Q

What are the side effects of albuterol?

A

Tachycardia, tremor, tolerance

28
Q

What is mirabegron used for?

A

Overactive bladders

29
Q

What is the action of miraegron? What receptor does it work on?

A

Beta 3 adrenergic receptor agonist. Relaxes detrusor muscle

30
Q

What is the side effect of mirabegron?

A

Tachycardia, HT

31
Q

What is ephredrine used for?

A

nasal decongestant, hypotension. Also called pseudoephedrine.

32
Q

What is the effect of ephedrine?

A

Increases Norepinephrine release, causing prolonged CNS stimulation.

33
Q

What are the adverse reactions of ephedrine?

A

HTN, insomnia, tachyphylaxis

34
Q

What is amphetamine used for?

A

Obesity, narcolepsy, ADD

35
Q

What is the effect of amphetamine?

A

Increases amine release, causing CNS stimulation

36
Q

What are the side effects of amphetamine?

A

Restlessness, tremor, irritability, insomnia, dependency, tolerance

37
Q

What is tyramine used for?

A

Increased amine release

38
Q

What are the side effects of tyramines?

A

Hypotension…also beware of interaction with MAOIs

39
Q

What does cocaine do?

A

Local anesthetic

40
Q

How does cocaine work?

A

Inhibits NE, dopamine, CNS stimulant

41
Q

What are adverse reactions with cocaine?

A

Hypertension, AMI, arrhythmias, seizures

42
Q

Name three ways that antagonists can block adrenergic innervation (sympatholytics)

A
  1. Decrease sympathetic outflow from the brain
  2. Suppress nerve terminal NE
  3. Block post-synaptic receptors
43
Q

What do you use phentoamine for?

A

Decreasing blood pressure. It is rarely used.

44
Q

What do you use phenoxybenzamine for?

A

Peripheral vasospasm

45
Q

What are the adverse rxns with phenoxybenzamine?

A

Hypotension, tachycardia

46
Q

What is Prazosin used for?

A

Anti-HTN

47
Q

What are the adverse effects of prazosin?

A

First dose effect, large decrease in blood pressure causing postural hypotension

48
Q

What is propranolol used for?

A

Hypertension, IHD, arrhythmias

49
Q

What are the adverse rxns with propranolol?

A

Bradycardia, CCF, bronchoconstriction, hypoglycemia, aggravated PVD

50
Q

What do you use timolol for?

A

Glaucoma

51
Q

What are the adverse rxns with timolol?

A

Bronchoconstriction

52
Q

What is pindolol used for?

A

Beta blocker used in patients with bradycardia, or with poor cardiac drive

53
Q

What is sotalol used for?

A

Atrial and ventricular tachyarrhythmias

54
Q

What is the effect of sotalol?

A

Prolongs the cardiac action potential by blocking the K channels

55
Q

What is metoprolol used for?

A

HT, IHD

56
Q

What are adverse reactions associated with metoprolol?

A

Bronchoconstriction, bradycardia

57
Q

What is atenolol used for?

A

HT, renal excretion, IHD

58
Q

What are adverse reactions associated with atenolol?

A

Bronchoconstriction, bradycardia

59
Q

What is labetolol used for?

A

Hypertension, pheochromocytoma

60
Q

What are some adverse reactions with labetolol?

A

Hypotension, tachycardia

61
Q

What is carvedilol used for?

A

Treatment of heart failure. It’s been shown to improve survival through antioxidant effects

62
Q

Name the non-selective alpha agonists

A

Methoxamine

63
Q

What drug blocks alpha1, alpha 2, beta 1 and beta 2?

A

Labetolol

Pharm drugs HC (3 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions