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Pharmacology > Adrenergic Drugs > Flashcards

Adrenergic Drugs Flashcards

1
Q

Alpha receptor

A

Vasoconstricton (increase BP, decrease blood flow)

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2
Q

Beta 1 receptor

A

Increases rate and force of cardiac contraction

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3
Q

Beta 2 receptor

A

Relaxes non-vascular smooth muscle
Causes bronchodilation, reduced internal muscle tone, vasodilation

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4
Q

Epinephrine

A

Binds to alpha, beta 1 and 2
Increases cardiac output and vasoconstriction

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5
Q

Norepinephrine

A

Binds well to alpha and beta 1, less well to beta 2
Increase cardiac output and vasoconstriction

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6
Q

Clonidine

A

Alpha 2 receptors in CNS to reduce symphathetic outflow
Anti hypertensive

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7
Q

Brimonidine

A

Alpha 2 agonist
Used to treat glaucoma (get rid of excess liquids in the eye)

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8
Q

Isoproternol

A

Nonselective beta agonist
Increases cardiac output, vasodilation
Helps treat bradycardia and heartblock

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9
Q

Albuterol

A

Long acting beta 2 agonist (vasodilation,bronchodilation)
Treats asthma and COPD

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10
Q

Terbutaline

A

Long acting beta 2 agonist (vasodilation, bronchodilation)
Treats asthma

Better than isoproternol for bronchial effects (less effect on the heart)

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11
Q

Tyramine

A

Indirect sympathomimetic
Increase sympathetic outflow
Found in food and drinks- large release of norepinephrine- hypertensive crisis

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12
Q

Amphetamine

A

Indirect sympathomimetic
CNS Stimulant
Treats ADHD, narcolepsy

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13
Q

Cocaine

A

Inhibits NET (norepinephrine accumulates in the cleft)
CNS stimulant

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14
Q

Prazosin

A

Alpha 1 selective antagonist
Lowers BP, can cause orthostatic hypotension (low BP cause by sitting or lying down)
Used to treat hypertension

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15
Q

Yohimbine

A

Alpha 2 selective receptor antagonists
Increases sympathetic outflow from CNS
Increases BP, HR by blocking CNS postsynaptic receptors

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16
Q

Propranolol

A

Nonselective beta blocker
Binds well to receptor, weak physiological response
Used to treat hypertension, cardiac arrhythmias

17
Q

Timolol

A

Relatively short acting Nonselective beta blocker
Used to treat hypertension, angina, glaucoma

18
Q

Pindolo

A

Partial agonist Nonselective beta receptor blockers
Used to treat hypertension, angina

19
Q

Atenolol

A

Beta 1 selective blocker
Used to treat hypertension, angina

20
Q

Carvedilol

A

Blocks alpha 1 receptor, beta blocker
Used to treat hypertension, CHF

21
Q

Nebivolol

A

Triggers nitric oxide release by epithelial cells, beta 1 blocker
Used to treat hypertension

22
Q

Metyrosine

A

Inhibit rate limiting step in synthesis of catecholamines
Used to treat hypertension, pheochromocytoma

23
Q

Reserpine

A

Irreversibly inhibit VMAT
Depletes stores of catecholamine greatly within hours
Used to treat hypertension, psychosis

24
Q

Methyldopa

A

DOPA decarboxylase
Used to treat hypertension

Pharmacology (3 decks)

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