Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Prototype Drugs > Adrenergic-Blocking Drugs Chapter 19 > Flashcards

Adrenergic-Blocking Drugs Chapter 19 Flashcards

1
Q

Atenolol (Tenormin) uses

A

Therapeutic: antianginals, antihypertensives, Pharmacologic: beta blockers

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Atenolol (Tenormin) dose

A

Route/Dosage: PO (adult): Antianginal- 50 mg once daily; may be increased after 1 week to 100mg/day (up to 200mg/day. Antihypertensive- 25-50 mg/day; may be increased after 2 wk to 50-100 mg/day. MI- 50mg, then 50 mg 12h later, then 100mg/day as a single dose or in 2 divided doses for 6-9 days or until hospital discharge.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Atenolol (Tenormin) side effects

A

Adverse Reaction/Side effect: CNS: fatigue, weakness. CV BRADYCARDIA, HEART FAILURE, PULMONARY EDEMA. GU- erectile dysfunction.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Atenolol (Tenormin) nursing implications

A

NI: Assessment- Monitor BP, ECG, and pulse frequently during dosage adjustment period and periodically throught therapy. Monitor intake and output ratios and daily weights. Assess routinely for heart failure (HF) (dyspnea, rales/crackles, weight gain, peripheral edema, jugular venous distention).
Lab Test considerations- May cause increase BUN, serum lipoprotein, potassium, triglyceride, and uric acid levels.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Atenolol (Tenormin) interactions

A

Interacations- DD- General ansethesia, IV phenytoin, and verapamil may cause additive myocardial depression. Additive bradycardia may occur with digoxin. Additive hypotension may occur with other antihypertensives, acute ingestion of alcohol, or nitrates. Concurrant use with amphetamine, cocaine, ephedrin, epinephrine, norepinephrine, phenylephrine, or pseudoephedrine may result in unopposed (excessive hypertension, bradycardia). Concurrent thryoid administration may lower effectiveness. May alter effectiveness of insulins or oral hypoglycemic agents. May lower the effectiveness of theophylline. May lower the beneficial beta1-cardiovascular effects of dopamine or dobutamine. Use cautiously within 14 days of MAO inhibitor therapy (may result in hypertension).

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Atenolol (Tenormin) contraindications

A

Contraindications- Uncompensated HF, Pulmonary Edema, Cardiogenic Shock, Bradycardia, or heart block. Atropine can be given to counteract BRADYCARDIA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

esmolol (Brevibloc) uses

A 
Therapeutic: antiarrhythmics (class II)
Pharmacologic: beta blockers
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

esmolol (Brevibloc) dose

A

.Dosage: IV (adults) Antiarrhythmic- 500mcg/kg loading dose over 1 min. initially, followed by 50 mcg/kg/min infusion for 4 min; if no response within 5 min, give 2nd loading dose of 500mcg/kg over 1 min. and increase infusion rate by 50 mcg/kg/min increments (not to exceed 200 mcg/kg/min for 48 hr).
IV (children) Antiarrhythmic- 50 mcg/kg/min, may be increased q 10 min up to 300 mcg/kg/min.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

esmolol (Brevibloc) adverse reactions

A

Adverse Reactions/Side Effects- Fatigue, hypotension

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

esmolol (Brevibloc) nursing implications

A

NI: Assessment- Monitor BP, ECG, and pulse frequently during dosage adjustment period and periodically during therapy. Hypotension risk is greatest during the first 30 minutes of initiation. Monitor intake and output ratios and daily weights. Assess routinely for rales/crackles, weight gain, peripheral edema, jugular vein distention. Assess infusion site frequently. Monitor for signs of overdose (bradycardia, severe dizziness, severe drowsiness, dyspnea, bluish fingernails or palms, seizures.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

esmolol (Brevibloc) interactions

A

Interactions: DD- General anesthesia, IV phenytoin, and verapamil may cause additive myocardial depression. Additive bradycardia may occur with digoxin. Additive hypotension may occur with other antihypertensives, acute ingestion of alcohol, or nitrates. Concurrent use with amphetamine, cocaine, ephedrine, epinephrine, norepiephrine, phenylephrine, or pseudoephedrine may result in hypertension, bradycardia. Concurrent thyroid hormone administration may reduce effectiveness. May alter the effectiveness of insulins or oral hypoglycemic agents. May reduce effectiveness of theophylline. May reduce beneficial beta cardiovascular effects of dopamine or dobutamine. Use cautiously within 14 days of MAO inhibitor therapy.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

esmolol (Brevibloc) contraindications

A

Contraindications- Uncompensated HF; Pulmonary Edema, Cardiogenic shock, Bradycardia, or heart block, Known alcohol intolerance. Atropine can be given to counteract BRADYCARDIA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

metoprolol (Lopressor, Toprol XL) uses

A

Therapeutic- antianginals, antihypertensives

Pharmacologic- beta blocker

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

metaprolol (Lopressor, Toprol XL) dose

A

PO (Adults)- Antihypertensive/antianginal- 25-100 mg/day as a single dose initially or 2 divided doses; may be increased q 7 days as needed up to 450mg/day (immediate release) or 400mg/day (extended release) (for angina, give in divided doses). Extended-release products are given once daily. MI- 25-50 mg (starting 15 min after last IV dose) q6hr for 48 hr, then 100mg twice daily. Heart Failure-12.5-25 mg once daily (of extended-release) can be doubled every 2 wk up to 200 mg/day. Migraine prevention- 50-100mg 2-4xday.
IV (Adult)- MI- 5 mg q 2min for 3 doses, followed by oral dosing.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

metaprolol (Lopressor, Toprol XL) side effects

A

Adverse Reaction/Side effects- fatigue, weakness, BRADYCARDIA, HF, PULMONARY EDEMA, erectile dysfunction. Atropine can be given to manage BRADYCARDIA.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

metaprolol (Lopressor, Toprol XL) nursing implications

A

NI- Assessment- Monitor BP, ECG and pulse frequently during dosage adjustment. Monitor vital signs and ECG every 5-15 minutes during and for several hours after parenteral administration. If HR is >40 bpm, especially if cardiac output is also decreased, administer atropine 0.25-0.5mg IV. Monitor intake and output ratios and daily weights. Assess routinely for signs and symptoms of HF (dyspnea, rales/crackles, weight gain, peripheral edema, jugular venous distention).
Lab test considerations- May cause increase BUN, serum lipoprotein, potassium, triglyceride, and uric acid levels. May cause increase ANA tilter, blood glucose levels, serum alkaline phosphatase, LDH, AST and ALT levels.

17
Q

metaprolol (Lopressor, Toprol XL) interactions

A

Interactions: DD- General anesthesia, IV phenytoin, and verapamil may cause additive myocardial depression. Additive bradycardia may occur with digoxin. Additive hypotension may occur with other antihypertensives, acute ingestion of alcohol, or nitrates. Concurrent use with amphetamine, cocaine, ephedrine, epinephrine, norepiephrine, phenylephrine, or pseudoephedrine may result in hypertension, bradycardia. Concurrent thyroid hormone administration may reduce effectiveness. May alter the effectiveness of insulins or oral hypoglycemic agents. May reduce effectiveness of theophylline. May reduce beneficial beta cardiovascular effects of dopamine or dobutamine. Use cautiously within 14 days of MAO inhibitor therapy.

18
Q

metaprolol (Lopressor, Toprol XL) contraindications

A

Contraindications- Uncompensated HF, Pulmonary edema, Cardiogenic shock, Bradycardia, heart block, or sick sinus syndrome (in absence of a pacemaker).

19
Q

phentolamine (Oraverse, Regitine, Rogitine) uses

A

Therapeutic- agents for pheochromocytoma
Pharmacologic- alpha-andrenergic blockers.
Used to manage high BP caused by pheochromocytoma.

20
Q

phentolamine (Oraverse, Regitine, Rogitine) dose

A

Dosage- IV (adult)- 5 mg given 1-2 hr preop, repeated as necessary. May be infused at a rate of 0.5-1mg/min during surgery.

21
Q

phentolamine (Oraverse, Regitine, Rogitine) side effects

A

Adverse Reaction/Side effect- CEREBROVASCULAR SPASM, HYPOTENSION, MI, angina, arrhythmias, tachycardia, abdominal pain, diarrhea, nausea, vomiting.

22
Q

phentolamine (Oraverse, Regitine, Rogitine) nursing implications

A

NI- Assessment- Monitor BP, pulse, and ECG every 2 min until stable during IV administration. If hypotensive crisis occurs, epinephrine is contraindicated and may cause paradoxic further decrease in BP; norepinephrine may be used.

23
Q

phentolamine (Oraverse, Regitine, Rogitine) interactions

A

Interaction; DD- Antagonizes the effects of alpha-adrenergic stimulants. May lower pressor response to ephedrine or phenylephrine. Sever hypotension may occur with concurrent use of epinephrine or methoxamine. Lower peripheral vasoconstriction from high doses of dopamine.

24
Q

phentolamine (Oraverse, Regitine, Rogitine) contraindications

A

Contraindications- history of Myocardial Infarction (MI), and coronary artery disease.

25
Q

propranolol (Inderal, Inderal LA, InnoPran XL) uses

A

Therapeutic- antianginals, antiarrhythmics (Class II), antihypertensives, vascular headache, suppressants.
Pharmacologic- beta blockers

26
Q

propranolol (Inderal, Inderal LA, InnoPran XL) dose

A

Dosage- PO (Adult) 80-320 mg/day in 2-4 divided doses or once day as extended/sustained-released capsules.

27
Q

propranolol (Inderal, Inderal LA, InnoPran XL) side effects

A

Adverse Reaction/Side effect- fatigue, weakness, ARRHYTHMIA, BRADYCARDIA, HF, PULMONARY EDEMA, erectile disfunction, ERYTHEMA MULTIFORME, EXFOLIATIVE DERMATITIS, STEVENS-JOHNSON SYNDROME, TOXIC EPIDERMAL, NECROLYSIS, ANAPHYLAXIS.

28
Q

propranolol (Inderal, Inderal LA, InnoPran XL) nursing implications

A

NI- Assessment, Monitor BP and pulse frequently, abrupt withdrawal may precipitate life-threatening arrhythmias, hypertension, or myocardial ischemia.
Pediatric- assess pt. for signs and symptoms of hypoglycemia, particularly when oral foods and fluids are restricted. Monitor intake and output ratios. Assess for rash periodically during therapy. May cause Stevens-Johnson syndrome.
Lab Test considerations May cause increase BUN, serum lipoprotein, potassium, triglyceride, and uric acid levels. May causes increase in ANA tilters, an increase or decrease in blood glucose levels, hypoglycemia may be accompanied by precipitous increased BP.

29
Q

propranolol (Inderal, Inderal LA, InnoPran XL) interactions

A

Interactions: DD- General anesthesia, IV phenytoin, and verapamil may cause additive myocardial depression. Additive bradycardia may occur with digoxin. Additive hypotension may occur with other antihypertensives, acute ingestion of alcohol, or nitrates. Concurrent use with amphetamine, cocaine, ephedrine, epinephrine, norepiephrine, phenylephrine, or pseudoephedrine may result in hypertension, bradycardia. Concurrent thyroid hormone administration may reduce effectiveness. May alter the effectiveness of insulins or oral hypoglycemic agents. May reduce effectiveness of theophylline. May reduce beneficial beta cardiovascular effects of dopamine or dobutamine. Use cautiously within 14 days of MAO inhibitor therapy. Cimetidine may increase blood levels and toxicity. Concurrent NSAIDs may lower antihypertensive action. Smoking increase metabolism and decreases effects; smoking cessation may increase effects. May increase levels of lidocaine and bupivacaine.

30
Q

propranolol (Inderal, Inderal LA, InnoPran XL) contraindications

A

Contraindications- Uncompensated HF; pulmonary edema; Cardiogenic shock; Bradycardia, sick sinus syndrome, or heart block (unless pacemaker present).

Prototype Drugs (9 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions