adrenergic blockers Flashcards
1
Q
Acetobuotol
A
B1 partial agonist local anesthetic low LS 3-4 H-L
2
Q
Atenolol
A
B1 agonist -competitive -HTN, angina, arrh. -oral low LS 6-9 hr
3
Q
Carvedilol
A
no selectivity
moderate LS
7-10
4
Q
Esmolol
A
B1
low LS
10 mins
5
Q
Labetalol
A
no selectivity, block both A and B partial agonist for B2 -HTN, hypertensive emergencies -oral, IV local anesthetic Low LS 5 hrs
6
Q
Metoprolol
A
B1
local anesthetic
moderate LS
3-4 hr
7
Q
Nadolol
A
No selectivity
Low LS
14-24 hr
8
Q
Pindolol
A
No selectivity partial agonist local anesthetic moderate LS 3-4 hr
9
Q
propranolol
A
no selectivity -competitive block -angina, arrh, HTN, migraine, tremor -oral, IV -because not partial agonist activity, causes bronchospasm local anesthetic high LS 3.5-6 hr
10
Q
timolol
A
no selectivity
-decrease secretion of aqueous humor from ciliary epithelium
moderate LS
4-5 hr
11
Q
phentolamine
A
non-selective alpha blocker
- oral, IV, short H-L: 204 hours
- competitive antagonist at alpha receptors
- pheochromocytoma
- side effects: orthostatic hypotension, reflex tachycardia
12
Q
phenoxybenzamine
A
non-selective alpha blocker -oral, short h-l but long duration 24-48 hr irreversible binding to alpha receptors -pheo, carcinoid, raynauds phenomenon side effects: ortho, GI irritation
13
Q
Prazosin
A
alpha selective blocker
- competitive antagonist
- treat: HTN, benign prostatic hyperplasia
- oral, dur. 8 hours
- side effects: orthostatic HTN,
14
Q
drugs like prazosin
A
doxazosin, terazosin, tamsulosin, sildosin
15
Q
Yohimbine
A
A2 selective blocker
-competitive antagonist
-oral
SE: tachycardia, GI upset
