Adrenergic Agonists

Question 0

Catecholamines

Answer 0

Cannot be used orally, brief duration of action, cannot cross the blood brain barrier

Question 1

Adrenergic agonists

Answer 1

Produce their effects by activating adrenergic receptors; sympathomimetic
-Broad spectrum of application: congestive heart failure (CHF), asthma, preterm labor

Question 2

Noncatechlamines

Answer 2

Can be given orally, metabolized slowly by MAO/longer half life, more able to cross blood brain barrier

Question 3

Albuterol

Answer 3

Beta2 receptors only

Question 4

Isoproterenol

Answer 4

Beta1 and beta1 receptors

Question 5

Epinephrine

Answer 5

Alpha1, alpha2, beta1, and beta2

Question 6

Clinical applications of alpha1

Answer 6

Vasoconstriction, mydriasis

Question 7

Drugs capable of activating alpha1 receptors

Answer 7

Epinephrine, norepinephrine, phenylephrine, dopamine

Question 8

Therapeutic applications of alpha1 activation

Answer 8

Hemostasis, nasal decongestion, adjunct to local anethesia, elevation of blood pressure, mydriasis

Question 9

Adverse effects of alpha1 activation

Answer 9

Hypertension, necrosis, bradycardia

Question 10

Alpha2 activation

Answer 10

CNS: reduction of sympathetic outflow to heart and blood vessels; relief of severe pain

Question 11

Beta1 activation therapeutic applications

Answer 11

Cardiac arrest, heart failure, shock, AV heart block