Adrenergic Agonists

Question 1

Class and action of norepi.

Answer 1

non-selective agonist (alpha1+2, beta1);

vasoconstriction, increase BP, direct increase HR, reflex decrease HR

Question 2

Therapeutic use of norepi.

Answer 2

hypotension

Question 3

Side effects of norepi.

Answer 3

hypertension, arrhythmias, HA

Question 4

Class and action of epi.

Answer 4

non-selective agonist (alpha1+2, beta1+2);

increase HR, increase contractility, increase BP, reflex decrease HR

Question 5

Therapeutic use of epi.

Answer 5

anaphylactic shock, with local anesthetics, glaucoma

Question 6

Side effects of epi.

Answer 6

palpitation, arrhythmias, HA, tremor

Question 7

Class and action of isoproterenol.

Answer 7

non-selective beta agonist (beta1+2);

decrease resistance, increase cardiac output, increase HR, bronchodilation

Question 8

Therapeutic use of isoproterenol.

Answer 8

bronchodilator/asthma, shock, heart block

Question 9

Side effects of isoproterenol.

Answer 9

palpitation, tachyarrhythmias, HA

Question 10

Class and action of dobutamine.

Answer 10

beta1-selective agonist;

increase contractility, increase HR, direct increase HR

Question 11

Therapeutic use of dobutamine.

Answer 11

cardiac decompensation, shock, heart block

Question 12

Side effects of dobutamine.

Answer 12

tachyarrhythmias, HTN

Question 13

Class and action of albuterol and terbutaline.

Answer 13

beta2-selective agonists;

relax bronchial and uterine smooth muscle

Question 14

Therapeutic use of albuterol and terbutaline.

Answer 14

bronchodilator/asthma, COPD

early labor

Question 15

Side effects of albuterol and terbutaline.

Answer 15

tachycardia, muscle tremor

Question 16

Class and action of phenylephrine and ephedrine

Answer 16

alpha1-selective agonist;

vasoconstriction

Question 17

Therapeutic use of phenylephrine and ephedrine

Answer 17

nasal congestion, postural hypotension

Question 18

Side effects of phenylephrine and ephedrine

Answer 18

HTN, reflex bradycardia

Question 19

Class and action of clonidine, alpha-methyldopa

Answer 19

alpha2-selective agonist;

decrease sympathetic outflow from CNS, decrease TPR

Question 20

Therapeutic use of clonidine, alpha-methyldopa

Answer 20

HTN, shock, withdrawal from drug dependence

Question 21

Side effects of clonidine, alpha-methyldopa

Answer 21

sedation

Question 22

Class and action of fenoldopam

Answer 22

DA (D1)-selective agonist;

vasodilation

Question 23

Therapeutic use of fenoldopam

Answer 23

HTN emergency, anuria

Question 24

Side effects of fenoldopam

Answer 24

postural hypotension

Question 25

Class and action of amphetamine

Answer 25

indirect-acting, release NE;

CNS stimulation, increase BP, increase HR

Question 26

Therapeutic use of amphetamine

Answer 26

ADHD, narcolepsy, recreation

Question 27

Side effects of amphetamine

Answer 27

HTN, insomnia, anxiety, arrhythmias

Question 28

Class and action of dopamine

Answer 28

Mixed acting: direct (D1, beta1, alpha1) and indirect (NE release);
vasodilation, increase GFR, increase HR, increase BP
(increasing dose leads to addition of beta1 and then alpha1 effects)

Question 29

Therapeutic use of dopamine

Answer 29

shock, renal failure, hypotension

Question 30

Side effects of dopamine

Answer 30

vasoconstriction (at high doses)