Adrenergic Agonists Flashcards

1
Q

Class and action of norepi.

A

non-selective agonist (alpha1+2, beta1);

vasoconstriction, increase BP, direct increase HR, reflex decrease HR

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Therapeutic use of norepi.

A

hypotension

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Side effects of norepi.

A

hypertension, arrhythmias, HA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Class and action of epi.

A

non-selective agonist (alpha1+2, beta1+2);

increase HR, increase contractility, increase BP, reflex decrease HR

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Therapeutic use of epi.

A

anaphylactic shock, with local anesthetics, glaucoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Side effects of epi.

A

palpitation, arrhythmias, HA, tremor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Class and action of isoproterenol.

A

non-selective beta agonist (beta1+2);

decrease resistance, increase cardiac output, increase HR, bronchodilation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Therapeutic use of isoproterenol.

A

bronchodilator/asthma, shock, heart block

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Side effects of isoproterenol.

A

palpitation, tachyarrhythmias, HA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Class and action of dobutamine.

A

beta1-selective agonist;

increase contractility, increase HR, direct increase HR

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Therapeutic use of dobutamine.

A

cardiac decompensation, shock, heart block

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Side effects of dobutamine.

A

tachyarrhythmias, HTN

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Class and action of albuterol and terbutaline.

A

beta2-selective agonists;

relax bronchial and uterine smooth muscle

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Therapeutic use of albuterol and terbutaline.

A

bronchodilator/asthma, COPD

early labor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Side effects of albuterol and terbutaline.

A

tachycardia, muscle tremor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Class and action of phenylephrine and ephedrine

A

alpha1-selective agonist;

vasoconstriction

17
Q

Therapeutic use of phenylephrine and ephedrine

A

nasal congestion, postural hypotension

18
Q

Side effects of phenylephrine and ephedrine

A

HTN, reflex bradycardia

19
Q

Class and action of clonidine, alpha-methyldopa

A

alpha2-selective agonist;

decrease sympathetic outflow from CNS, decrease TPR

20
Q

Therapeutic use of clonidine, alpha-methyldopa

A

HTN, shock, withdrawal from drug dependence

21
Q

Side effects of clonidine, alpha-methyldopa

22
Q

Class and action of fenoldopam

A

DA (D1)-selective agonist;

vasodilation

23
Q

Therapeutic use of fenoldopam

A

HTN emergency, anuria

24
Q

Side effects of fenoldopam

A

postural hypotension

25
Class and action of amphetamine
indirect-acting, release NE; | CNS stimulation, increase BP, increase HR
26
Therapeutic use of amphetamine
ADHD, narcolepsy, recreation
27
Side effects of amphetamine
HTN, insomnia, anxiety, arrhythmias
28
Class and action of dopamine
Mixed acting: direct (D1, beta1, alpha1) and indirect (NE release); vasodilation, increase GFR, increase HR, increase BP (increasing dose leads to addition of beta1 and then alpha1 effects)
29
Therapeutic use of dopamine
shock, renal failure, hypotension
30
Side effects of dopamine
vasoconstriction (at high doses)