Adrenergic Agents MOA only

Question 1

Beta 1 & 2 agonist –> increases HR, contractility, peripheral vasodilation, bronchodilation

Answer 1

Isoproterenol

Question 2

Beta 2 agonist –> bronchodilation; transcellular shifts of potassium into the cell

Answer 2

Albuterol

Question 3

alpha 2 agonist –> dec central adrenergic activity –> vasodilation

Answer 3

Methyldopa

Question 4

Irreversible alpha receptor antagonist –> dec BP; used to treat pheochromocytoma

Answer 4

Phenoxybenzamine

Question 5

selective alpha 1 antagonist –> dec BP & dec prostatic and bladder nec contraction

Answer 5

Prazosin

Question 6

Beta 1 & 2 antagonist –> dec HR & contractility, bronchoconstriction

Answer 6

Propanolol

Question 7

Selective Beta 1 antagonist –> dec HR & contractility

Answer 7

Metoprolol

Question 8

alpha agonist (high dose) --> vasoconstriction, inc HR & contractility; 
beta agonist (low dose)  --> bronchodilation

Answer 8

Epinephrine

Question 9

Potent alpha 1, alpha 2, beta 1 agonist –> inc contractility

Answer 9

Norepinephrine

Question 10

alpha agonist (high dose)  --> vasoconstriction, inc HR & contractility;
Beta & D1 agonst (low dose) --> promotes renal perfusion

Answer 10

Dopamine

Question 11

Stimulates the release of NE –> inc BP, bronchodilation, CNS stimulation

Answer 11

Ephedrine

Question 12

Blocks the Na+/K+ ATPase reap for reuptake of NE, S, & D; blocks voltage-gated Na+ channels

Answer 12

Cocaine

Question 13

Alpha 1 agonist –> systemic vasoconstriction

Answer 13

Phenylephrine

Question 14

Alpha 2 agonist –> dec central adrenergic activity –> vasodilation, dec CO & HR

Answer 14

Clonidine