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pharmaEx2 > Adrenergic > Flashcards

Adrenergic Flashcards

1
Q

Name three adrenergic direct alpha agonists

A

Epi, NE, Phenylepherine

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2
Q

Name one adrenergic direct alpha agonist selective for a1

A

Phenylepherine

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3
Q

Name three adrenergic direct beta agonist s

A

Isoprotenerol, Dobtamine, Albuterol

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4
Q

Name one adrenergic direct beta agonist selective for B1

A

Dobutamine

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5
Q

Name one adrenergic direct beta agonist selective for B2

A

Albuterol

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6
Q

Name two indirect beta agonists

A

Pseudoephiderine, cocaine

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7
Q

Which adrenergic drugs act on alpha 1 and vasoconstrict to increase BP?

A

Epi, NE, Phenylepherine

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8
Q

Which adrenergic drugs act on alpha 1 and vasoconstrict to relieve nasal congestion?

A

Pseudoephedrine, phenylepherine, oxymetazoline

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9
Q

Which adrenergic drug acts on alpha 1 and causes local vasoconstrict?

A

Epinepherine

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10
Q

Which adrenergic drugs act on beta 1 and cause bradyarrythmias?

A

Epi, isoprotenerol, dopamine

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11
Q

Which adrenergic drugs act on beta 2 and relax smooth muscle in anyphylaxis?

A

Epi

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12
Q

Which adrenergic drugs act on beta 2 and relax smooth muscle in asthma/COPD?

A

albuterol

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13
Q

Which adrenergic drugs act on beta 2 and relax smooth muscle in suppression of premature labor contractions?

A

Terbutaline

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14
Q

What is an adverse effect at an alpha-1 receptor?

A

Marked elevations in blood pressure

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15
Q

What is an adverse effect at an beta-1 receptor?

A

Increased cardiac work and myocardial O2 demand (angina, pro-arrythmic)

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16
Q

What is an adverse effect of alpha-1 and beta-1 on CNS?

A

Anxiety, restlessness, insomnia & paranoid state

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17
Q

Name an alpha1 selective blocker antagonist?

A

Doxazosin

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18
Q

Name a non-selective reversible alpha blocker antagonist

A

Phenotolamine

19
Q

Name a non-selective irreversible alpha blocker antagonist

A

Phenoxybenzamine

20
Q

Name a sympatholytic agent that is an inhibitors of Catecholamine Storage

A

Reserpine

21
Q

Name a sympatholytic agent that inhibits Tyrosine hydroxylase (rate-limiting)

A

Metyrosine

22
Q

Name two sympatholytic agents that inhibit DOPA decarboxylase

A

α-Methyldopa, Carbidopa

23
Q

Name a sympatholytic agent that inhibits Dopamine b-hydroxylase

A

Disulfiram

24
Q

Name a sympatholytic agent that is an Inhibitor of Catecholamine Release:

A

Bretylium

25
Q

If you see a drug that ends in “azosin” what does it do?

A

Its a selective anti-adrenergic agent (Prazosin, Terazosin, Doxazosin)

26
Q

These three meds are alpha-1 selective and are used to treat hypertension?

A

Prazosin, Terazosin, Doxazosin

27
Q

This med is a local vasoconstrictor and is alpha-1 selective reversible

A

Phenotolamine

28
Q

This med is an alpha irreversible used in the management of pheochromocytoma?

A

Phenoxybenzamine

29
Q

This med is a spinchter relaxer used in urinary obstruction for symptoms of BPH

A

Doxazosin or tamsulosin

30
Q

What class of drug do we worry about orthostatic hypotension in?

A

alpha 1 antagonists

31
Q

Which class of drug causes muscle tremors

A

beta-2

32
Q

which class of drug causes bradycardia and heart block?

A

beta-1

33
Q

What class of drug do we worry about sedation in?

A

alpha-2

34
Q

which class of meds do we worry about bronchospasm in?

A

beta-2

35
Q

which class of med do we worry about dry mouth in?

A

alpha-2

36
Q

which class of drug do we worry about depressed mood-sleep disturbance in?

A

beta

37
Q

Name three beta 1 meds used in hypertension

A

Atenolol, Metoprolol, Labetalol

38
Q

Name 1 beta 1 med used in angina pectoris

A

metoprolol

39
Q

Name 2 beta 1 meds used in hyperthyroidism

A

metoprolol, propanolol

40
Q

Name two beta 1 meds used for arrythmias?

A

metoprolol, esmolol (IV)

41
Q

Name two beta 1 meds used for heart failure?

A

metoprolol, carvediolol

42
Q

Epinephrine “reversal” (a paradoxical decrease in blood pressure when systemic epinephrine is given) occurs if epinephrine is given with a drug that blocks which receptor type:

A

alpha 1 adrenergic

43
Q

The direct actions of epinephrine to increase total peripheral resistance and systolic blood pressure would be further increased if the patient was also given a drug that blocks which receptor:

A

b2 adrenergic

Carvedilol, Propranolol. Labetalol

44
Q

This adrenergic antagonist med is used in hypertension and for opoid withdrawl symptoms

A

clonidine (alpha-2)

Decreases NE and dec SNS activity

pharmaEx2 (3 decks)

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