Adrenergic

Question 1

Name three adrenergic direct alpha agonists

Answer 1

Epi, NE, Phenylepherine

Question 2

Name one adrenergic direct alpha agonist selective for a1

Answer 2

Phenylepherine

Question 3

Name three adrenergic direct beta agonist s

Answer 3

Isoprotenerol, Dobtamine, Albuterol

Question 4

Name one adrenergic direct beta agonist selective for B1

Answer 4

Dobutamine

Question 5

Name one adrenergic direct beta agonist selective for B2

Answer 5

Albuterol

Question 6

Name two indirect beta agonists

Answer 6

Pseudoephiderine, cocaine

Question 7

Which adrenergic drugs act on alpha 1 and vasoconstrict to increase BP?

Answer 7

Epi, NE, Phenylepherine

Question 8

Which adrenergic drugs act on alpha 1 and vasoconstrict to relieve nasal congestion?

Answer 8

Pseudoephedrine, phenylepherine, oxymetazoline

Question 9

Which adrenergic drug acts on alpha 1 and causes local vasoconstrict?

Answer 9

Epinepherine

Question 10

Which adrenergic drugs act on beta 1 and cause bradyarrythmias?

Answer 10

Epi, isoprotenerol, dopamine

Question 11

Which adrenergic drugs act on beta 2 and relax smooth muscle in anyphylaxis?

Answer 11

Epi

Question 12

Which adrenergic drugs act on beta 2 and relax smooth muscle in asthma/COPD?

Answer 12

albuterol

Question 13

Which adrenergic drugs act on beta 2 and relax smooth muscle in suppression of premature labor contractions?

Answer 13

Terbutaline

Question 14

What is an adverse effect at an alpha-1 receptor?

Answer 14

Marked elevations in blood pressure

Question 15

What is an adverse effect at an beta-1 receptor?

Answer 15

Increased cardiac work and myocardial O2 demand (angina, pro-arrythmic)

Question 16

What is an adverse effect of alpha-1 and beta-1 on CNS?

Answer 16

Anxiety, restlessness, insomnia & paranoid state

Question 17

Name an alpha1 selective blocker antagonist?

Answer 17

Doxazosin

Question 18

Name a non-selective reversible alpha blocker antagonist

Answer 18

Phenotolamine

Question 19

Name a non-selective irreversible alpha blocker antagonist

Answer 19

Phenoxybenzamine

Question 20

Name a sympatholytic agent that is an inhibitors of Catecholamine Storage

Answer 20

Reserpine

Question 21

Name a sympatholytic agent that inhibits Tyrosine hydroxylase (rate-limiting)

Answer 21

Metyrosine

Question 22

Name two sympatholytic agents that inhibit DOPA decarboxylase

Answer 22

α-Methyldopa, Carbidopa

Question 23

Name a sympatholytic agent that inhibits Dopamine b-hydroxylase

Answer 23

Disulfiram

Question 24

Name a sympatholytic agent that is an Inhibitor of Catecholamine Release:

Answer 24

Bretylium

Question 25

If you see a drug that ends in "azosin" what does it do?

Answer 25

Its a selective anti-adrenergic agent (Prazosin, Terazosin, Doxazosin)

Question 26

These three meds are alpha-1 selective and are used to treat hypertension?

Answer 26

Prazosin, Terazosin, Doxazosin

Question 27

This med is a local vasoconstrictor and is alpha-1 selective reversible

Answer 27

Phenotolamine

Question 28

This med is an alpha irreversible used in the management of pheochromocytoma?

Answer 28

Phenoxybenzamine

Question 29

This med is a spinchter relaxer used in urinary obstruction for symptoms of BPH

Answer 29

Doxazosin or tamsulosin

Question 30

What class of drug do we worry about orthostatic hypotension in?

Answer 30

alpha 1 antagonists

Question 31

Which class of drug causes muscle tremors

Answer 31

beta-2

Question 32

which class of drug causes bradycardia and heart block?

Answer 32

beta-1

Question 33

What class of drug do we worry about sedation in?

Answer 33

alpha-2

Question 34

which class of meds do we worry about bronchospasm in?

Answer 34

beta-2

Question 35

which class of med do we worry about dry mouth in?

Answer 35

alpha-2

Question 36

which class of drug do we worry about depressed mood-sleep disturbance in?

Answer 36

beta

Question 37

Name three beta 1 meds used in hypertension

Answer 37

Atenolol, Metoprolol, Labetalol

Question 38

Name 1 beta 1 med used in angina pectoris

Answer 38

metoprolol

Question 39

Name 2 beta 1 meds used in hyperthyroidism

Answer 39

metoprolol, propanolol

Question 40

Name two beta 1 meds used for arrythmias?

Answer 40

metoprolol, esmolol (IV)

Question 41

Name two beta 1 meds used for heart failure?

Answer 41

metoprolol, carvediolol

Question 42

Epinephrine “reversal” (a paradoxical decrease in blood pressure when systemic epinephrine is given) occurs if epinephrine is given with a drug that blocks which receptor type:

Answer 42

alpha 1 adrenergic

Question 43

The direct actions of epinephrine to increase total peripheral resistance and systolic blood pressure would be further increased if the patient was also given a drug that blocks which receptor:

Answer 43

b2 adrenergic | Carvedilol, Propranolol. Labetalol

Question 44

This adrenergic antagonist med is used in hypertension and for opoid withdrawl symptoms

Answer 44

clonidine (alpha-2) Decreases NE and dec SNS activity