adrenals Flashcards
1
Q
describe the pathway for adrenaline synthesis…
A
adrenaline is a catecholamine synthesised from tyrosine
consists of benzene ring and OH groups.
tyrosine hydroxylase is the rate limiting step.
tyrosine comes from aa phenylalanine
adrenaline is packed into granules and released on sympathetic stimulation.
2
Q
how are catecholamine metabolised?
A
half life is around 3-5 mins
metabolised by COMT and MAO into VMA
