Adrenaline 1:1000 Flashcards
In what clinical situation would you administer adrenaline 1:1,000? (2)
Anaphylaxis
Life-threatening asthma with failing ventilation and continued deterioration despite nebuliser therapy
When administered what affect does adrenaline have on the body?
Adrenaline stimulates alpha and beta adrenoreceptors which increases heart rate and contractility, causes vasoconstriction, relieves bronchospasm and suppresses histamine.
Why is adrenaline 1:1,000 useful in the treatment of anaphylaxis?
This is useful in anaphylaxis to reduce swelling in the airways and raise blood pressure
Why is adrenaline 1:1,000 useful in the treatment of life-threatening asthma?
In life-threatening asthma, it is given for its useful bronchodilatory effects
Anaphylaxis is a severe allergic reaction characterised by…? (3)
Sudden onset and rapid progression of symptoms (most reactions occur over several minutes)
Life-threatening airway and/or breathing and/or circulation problems
Skin and/or mucosal changes (flushing, urticaria, angioedema): although these can be subtle or absent in up to 20% of reactions
Cautions for adrenaline 1:1,000 administration?
Severe hypertension may occur in patients on non-cardioselective beta-blockers (e.g. Propranolol)
How and where is adrenaline 1:1,000 administered?
Intramuscular – antero-lateral aspect of thigh
Is there an exclusion for adrenaline 1:1,000 administration based on age?
No, even new born babies can receive adrenaline 1:1,000
Initial dose of adrenaline 1:1,000 for ≥12 years and adult?
500 micrograms
0.5ml of 1 milligram in 1 ml (1:1,000)
Is the initial dose of adrenaline 1:1,000 and repeat doses the same?
Yes
Across the board for all ages, the initial dose is the same as all repeat doses given
How many doses of adrenaline 1:1,000 can be administered?
No limit / max dose
This applies to all ages
Dose interval for adrenaline 1:1,000?
5 minutes
Do you dilute adrenaline 1:1,000 with sodium chloride before administration?
No
