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ENDOCRINOLOGY > Adrenalcortical excess (inc. Cushings) > Flashcards

Adrenalcortical excess (inc. Cushings) Flashcards

1
Q
A

gluconeogenosis
immunosuppressive
carb, protein, lipid metabolism increased

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2
Q
A

sodium balance

potassium balance

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3
Q
A

increased sodium reabsorption

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4
Q
A

increased secretion of potassium

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5
Q
A

cortisol

androgens

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6
Q
A

chronic glucocorticoid secretion (loss of circadian cycle)

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7
Q
A

circadian (highest on waking)

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8
Q
A

ACTH secreting pituitary tumour adenoma

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9
Q
A

hyperplasia

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10
Q
A

Small cell lung cancers can produce ectopic ACTH

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11
Q
A

T

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12
Q
A

increased weight

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13
Q
A

central obesity
moon face
buffalo hump
osteoporosis

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14
Q
A

too much variance throughout the day

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15
Q
A

overnight dexamethasone test

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16
Q
A

binds to the glucocorticoid receptors in the posterior pituitary suppressing release of ACTH

17
Q
A

50

18
Q
A

50

19
Q
A

48 hour dexamethasone suppression test

20
Q
A

confirm the overnight dexamethasone test

21
Q
A

distinguish between pituitary and other causes of Cushings

22
Q
A

pituitary

23
Q
A

ectopic ACTH (usually very high ACTH)

24
Q
A

primary adrenal adenoma

25
Q
A

CT of the adrenal

26
Q
A

posterior pituitary adenoma

27
Q
A

ectopic ACTH production (small cell lung cancer)

28
Q
A

trans-sphenoidal surgery of post. pit

29
Q
A

adrenalectomy

30
Q
A

surgery if localised

31
Q

[cushings]: increased skin pigmentation is only seen in very high levels of ACTH. Which cause is this a ‘unique’ characteristic of

A

ectopic

produces very high levels of ACTH

32
Q
A

steroids (exogenous)

endogenous rare

ENDOCRINOLOGY (19 decks)

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